Dimethyl sulphoxide relaxes rabbit detrusor muscle by decreasing the Ca 2+ sensitivity of the contractile apparatus

British Journal of Pharmacology

Volumn 151, Issue 7, 2007, Pages 1014-1024

  Shiga, K I ^a   Hirano, K ^a   Nishimura, J ^a   Niiro, N ^a   Naito, S ^b   Kanaide, H ^a,b  

^a KYUSHU UNIVERSITY   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

Author keywords

Bladder; Calcium sensitivity; Dimethyl sulphoxide; Smooth muscle

Indexed keywords

ALPHA TOXIN; CALCIUM ION; CALYCULIN A; CARBACHOL; DIMETHYL SULFOXIDE; MYOSIN LIGHT CHAIN; PHOSPHATE; PHOSPHOTRANSFERASE; POTASSIUM ION;

ANIMAL TISSUE; ARTICLE; CELL MEMBRANE DEPOLARIZATION; CELL PERMEABILIZATION; CONTROLLED STUDY; DESENSITIZATION; DETRUSOR MUSCLE; DRUG EFFECT; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME METABOLISM; MALE; MYOFILAMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RABBIT; SMOOTH MUSCLE CONTRACTION; SMOOTH MUSCLE FIBER; SMOOTH MUSCLE RELAXATION; SMOOTH MUSCLE TONE;

ACTINS; ANALGESICS, NON-NARCOTIC; ANDROSTADIENES; ANIMALS; AORTA; CALCIUM; CALMODULIN; CARBACHOL; CHOLINERGIC AGONISTS; DIMETHYL SULFOXIDE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; MALE; MUSCLE CONTRACTION; MUSCLE RELAXATION; MUSCLE, SMOOTH; MYOSIN LIGHT CHAINS; MYOSIN-LIGHT-CHAIN KINASE; PHOSPHATES; PHOSPHOLIPASE C; PHOSPHORYLATION; POTASSIUM CHLORIDE; RABBITS; RATS; URINARY BLADDER;

EID: 34547594518     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0707317     Document Type: Article

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