Local delivery of osteoprotegerin inhibits mechanically mediated bone modeling in orthodontic tooth movement

Bone

Volumn 41, Issue 3, 2007, Pages 446-455

  Dunn, Matthew D ^a   Park, Chan Ho ^b,c   Kostenuik, Paul J ^d   Kapila, Sunil ^a   Giannobile, William V ^b,c,e  

^a UNIVERSITY OF MICHIGAN SCHOOL OF DENTISTRY   (United States)

^b School of Dentistry   (United States)

^c UNIVERSITY OF MICHIGAN   (United States)

^d AMGEN INC   (United States)

^e Michigan Center for Oral Health Research   (United States)

Author keywords

Micro computed tomography; OPG; Osteoclast; RANKL inhibitor; Tooth movement

Indexed keywords

BIOLOGICAL MARKER; NICKEL; OSTEOPROTEGERIN; RECOMBINANT OSTEOPROTEGERIN FC FRAGMENT FUSION PROTEIN; THROMBIN RECEPTOR ACTIVATING PEPTIDE; THROMBIN RECEPTOR ACTIVATING PEPTIDE 5B; TITANIUM; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOLOGICAL MODEL; BIOMECHANICS; BONE DENSITOMETRY; COMPARATIVE STUDY; CONTROLLED STUDY; DEVICE; DRUG DOSE COMPARISON; DRUG MEGADOSE; DRUG POTENCY; ENZYME LINKED IMMUNOSORBENT ASSAY; INCISOR; LOW DRUG DOSE; MALE; MAXILLA; MICRO-COMPUTED TOMOGRAPHY; MOLAR TOOTH; MORPHOMETRICS; NONHUMAN; ORTHODONTICS; OSTEOLYSIS; PROTEIN BLOOD LEVEL; RAT; STATISTICAL SIGNIFICANCE;

ACID PHOSPHATASE; ANIMALS; BONE REMODELING; ENZYME-LINKED IMMUNOSORBENT ASSAY; IMMUNOHISTOCHEMISTRY; ISOENZYMES; MALE; OSTEOCLASTS; OSTEOPROTEGERIN; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT FUSION PROTEINS; TOMOGRAPHY, X-RAY COMPUTED; TOOTH MOVEMENT;

EID: 34547590675     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2007.04.194     Document Type: Article

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