Blockade of gap junction coupling by glycyrrhetinic acids in guinea pig cochlear artery: A whole-cell voltage- and current-clamp study

British Journal of Pharmacology

Volumn 151, Issue 7, 2007, Pages 1049-1060

  Guan, B C ^a   Si, J Q ^a,b   Jiang, Z G ^a,c  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b SHIHEZI UNIVERSITY   (China)

^c OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Acetylcholine; Arteriole; Cochlea; EDHF; Gap junction; Membrane input conductance; Vascular

Indexed keywords

18ALPHA GLYCYRRHETINIC ACID; ACETYLCHOLINE; GLYCYRRHETINIC ACID;

ANIMAL CELL; ANIMAL TISSUE; ARTERY; ARTICLE; CELL MEMBRANE DEPOLARIZATION; COCHLEA; CONTROLLED STUDY; DRUG EFFICACY; ELECTRIC ACTIVITY; GAP JUNCTION; GUINEA PIG; IC 50; MUSCLE FIBER MEMBRANE CONDUCTANCE; MUSCLE FIBER MEMBRANE RESISTANCE; NONHUMAN; POTASSIUM CONDUCTANCE; PRIORITY JOURNAL; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE; VOLTAGE CLAMP; WHOLE CELL;

4-AMINOPYRIDINE; ACETYLCHOLINE; ANIMALS; ARTERIES; BIOLOGICAL FACTORS; COCHLEA; DELAYED RECTIFIER POTASSIUM CHANNELS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC CONDUCTIVITY; GAP JUNCTIONS; GLYCYRRHETINIC ACID; GUINEA PIGS; MEMBRANE POTENTIALS; MUSCLE, SMOOTH, VASCULAR; PATCH-CLAMP TECHNIQUES; POTASSIUM; POTASSIUM CHANNELS, INWARDLY RECTIFYING; TETRAETHYLAMMONIUM; TIME FACTORS;

EID: 34547579274     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0707244     Document Type: Article

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