Hippocampal CA1 cell loss in a non-human primate model of transient global ischemia: A pilot study

Brain Research Bulletin

Volumn 74, Issue 1-3, 2007, Pages 164-171

  Hara, Koichi ^a   Yasuhara, Takao ^a   Matsukawa, Noriyuki ^a   Maki, Mina ^a   Masuda, Tadashi ^a   Yu, Guolong ^a   Xu, Lin ^a   Tambrallo, Laura ^a   Rodriguez, Nancy A ^a   Stern, David M ^b   Kawase, Takeshi ^c   Yamashima, Tetsumori ^d   Buccafusco, Jerry J ^a,e   Hess, David C ^a,e   Borlongan, Cesario V ^a,e  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^c KEIO UNIVERSITY   (Japan)

^d KANAZAWA UNIVERSITY   (Japan)

^e VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Apoptosis; Cell loss; Cerebral ischemia; Hippocampus; Non human primate

Indexed keywords

CA 074; CAD PROTEIN; CALCIUM; CALPAIN; CASPASE; CATHEPSIN; CYSTEINE PROTEINASE; CYSTEINE PROTEINASE INHIBITOR; DEOXYRIBONUCLEASE II; MICROTUBULE ASSOCIATED PROTEIN 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA ARCH; ARTICLE; BEHAVIOR; BRAIN DAMAGE; BRAIN ISCHEMIA; CELL DEATH; CELL LOSS; CONTROLLED STUDY; CONVULSION; DISEASE SEVERITY; HIPPOCAMPUS; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; MOTOR DYSFUNCTION; NERVE CELL; NEUROPROTECTION; NICK END LABELING; NISSL STAINING; NONHUMAN; PARALYSIS; PERIOPERATIVE PERIOD; PRIORITY JOURNAL; RHESUS MONKEY; RIGIDITY; SUBCLAVIAN ARTERY; SURVIVAL TIME; TRANSIENT ISCHEMIC ATTACK;

ANIMALS; CELL COUNT; CELL DEATH; DISEASE MODELS, ANIMAL; GLIAL FIBRILLARY ACIDIC PROTEIN; HIPPOCAMPUS; IN SITU NICK-END LABELING; ISCHEMIC ATTACK, TRANSIENT; MACACA MULATTA; MICROTUBULE-ASSOCIATED PROTEINS; NEUROGLIA; NEURONS; PILOT PROJECTS; STAINING AND LABELING; TIME FACTORS;

EID: 34547537219     PISSN: 03619230     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainresbull.2007.06.014     Document Type: Article

References (33)

1. Branston N.M., Symon L., Crockard H.A., and Pasztor E. Relationship between the cortical evoked potential and local cortical blood flow following acute middle cerebral artery occlusion in the baboon. Exp. Neurol. 45 (1974) 195-208
2. Brierley J.B., Brown A.W., Excell B.J., and Meldrum B.S. Brain damage in the rhesus monkey resulting from profound arterial hypotension. I. Its nature, distribution and general physiological correlates. Brain Res. 13 (1969) 68-100
3. Crowell R.M., Marcoux F.W., and DeGirolami U. Variability and reversibility of focal cerebral ischemia in unanesthetized monkeys. Neurology 31 (1981) 1295-1302
4. del Zoppo G.J., Copelnad B.R., Harker L.A., Waltz T.A., Zyroff J., Hanson S.R., and Battenberg E. Experimental acute thrombotic stroke in baboons. Stroke 17 (1986) 1254-1265
5. Frykholm P., Hillered L., Langstrom B., Persson L., Valtysson J., and Enblad P. Relationship between cerebral blood flow and oxygen metabolism, and extracellular glucose and lactate concentrations during middle cerebral artery occlusion and reperfusion: a microdialysis and positron emission tomography study in nonhuman primates. J. Neurosurg. 102 (2005) 1076-1084
6. Fujioka M., Nishio K., Miyamoto S., Hiramatsu K.I., Sakaki T., Okuchi K., Taoka T., and Fujioka S. Hippocampal damage in the human brain after cardiac arrest. Cerebrovasc. Dis. 10 (2000) 2-7
7. Fukuda S., and del Zoppo G.J. Models of focal cerebral ischemia in the nonhuman primate. ILAR J. 44 (2003) 96-104
8. Keuker J.I., Luiten P.G., and Fuchs E. Preservation of hippocampal neuron numbers in aged rhesus monkeys. Neurobiol. Aging 24 (2003) 157-165
9. Marshall J.W., and Ridley R.M. Assessment of cognitive and motor deficits in a marmoset model of stroke. ILAR J. 44 (2003) 153-160
10. Nemoto E.M., Bleyaert A.L., Stezoski S.W., Moossy J., Rao G.R., and Safar P. Global brain ischemia: a reproducible monkey model. Stroke 8 (1977) 558-564
11. Nemoto E.M., Jungreis C., Larnard D., Kuwabara H., Horowitz M., and Kassam A. Hyperthermia and hypermetabolism in focal cerebral ischemia. Adv. Exp. Med. Biol. 566 (2005) 83-89
12. Neubuerger K.T. Lesions of the human brain following circulatory arrest. J. Neuropathol. Exp. Neurol. 13 (1954) 144-160
13. Nudo R.J., Larson D., Plautz E.J., Friel K.M., Barbay S., and Frost S.B. A squirrel monkey model of poststroke motor recovery. ILAR J. 11 (2003) 161-174
14. Nudo R.J., Wise B.M., SiFuentes F., and Milliken G.W. Neural substrates for the effects of rehabilitative training on motor recovery after ischemic infarct. Science 272 (1996) 1791-1794
15. Petito C.K., and Lapinski R.L. Postischemic alterations in ultrastructural cytochemistry of neuronal Golgi apparatus. Lab. Invest. 55 (1986) 696-702
16. Pulsinelli W.A., Brierley J.B., and Plum F. Temporal profile of neuronal damage in a model of transient forebrain ischemia. Ann. Neurol. 11 (1982) 491-498
17. Rempel-Clower N.L., Zola S.M., Squire L.R., and Amaral D.G. Three cases of enduring memory impairment after bilateral damage limited to the hippocampal formation. J. Neurosci. 16 (1996) 5233-5255
18. Roitberg B., Khan N., Tuccar E., Kompoliti K., Chu Y., Alperin N., Kordower J.H., and Emborg M.E. Chronic ischemic stroke model in cynomolgus monkeys: behavioral, neuroimaging, and anatomical study. Neurol. Res. 25 (2003) 68-78
19. Schmahmann J.D., Rosene D.L., and Pandya D.N. Ataxia after pontine stroke: insights from pontocerebellar fibers in monkey. Ann. Neurol. 22 (2004) 585-589
20. Smith M.L., Auer R.N., and Siesjo B.K. The density and distribution of ischemic brain injury in the rat following 2-10 min of forebrain ischemia. Acta Neuropathol. (Berl.) 64 (1984) 319-332
21. Tabuchi E., Endo S., Ono T., Nishijo H., Kuze S., and Kogure K. Hippocampal neuronal damage after transient forebrain ischemia in monkeys. Brain Res. Bull. 29 (1992) 685-690
22. Tabuchi E., Ono T., Nishijo H., Endo S., and Kuze S. Ischemic neuronal damage specific to monkey hippocampus: histological investigation. Brain Res. Bull. 37 (1995) 73-87
23. Tsukada T., Watanabe M., and Yamashima T. Implications of CAD and DNase II in ischemic neuronal necrosis specific for the primate hippocampus. J. Neurochem. 79 (2001) 1196-1206
24. Vaitkevicius P.V., Lane M., Spurgeon H., Ingram D.K., Roth G.S., Egan J.J., Vasan S., Wagle D.R., Ulrich P., Brines M., Wuerth J.P., Cerami A., and Lakatta E.G. A cross-link breaker has sustained effects on arterial and ventricular properties in older rhesus monkeys. Proc. Natl. Acad. Sci. U.S.A. 98 (2001) 1171-1175
25. Wolin L.R., and Massopust Jr. L.C. Tolerance to arrest of cerebral circulation in the rhesus monkey. Exp. Neurol. 30 (1971) 103-115
26. Yamashima T. Implication of cysteine proteases calpain, cathepsin and caspase in ischemic neuronal death of primates. Prog. Neurobiol. 62 (2000) 273-295
27. Yamashima T., Kohda Y., Tsuchiya K., Ueno T., Yamashita J., Yoshioka T., and Kominami E. Inhibition of ischaemic hippocampal neuronal death in primates with cathepsin B inhibitor CA-074: a novel strategy for neuroprotection based on calpain-cathepsin hypothesis. Eur. J. Neurosci. 10 (1998) 1723-1733
28. Yamashima T., Saido T.C., Takita M., Miyazawa A., Yamano J., Miyakawa A., Nishijyo H., Yamashita J., Kawashima S., Ono T., and Yoshioka T. Transient brain ischaemia provokes Ca2+, PIP2 and calpain responses prior to delayed neuronal death in monkeys. Eur. J. Neurosci. 8 (1996) 1932-1944
29. Yamashima T., Tonchey A.B., Tsukada T., Saido T.C., Imajoh-Ohmi S., Momoi T., and Kominami E. Sustained calpain activation associated with lysosomal rupture executes necrosis of the postischemic CA1 neurons in primates. Hippocampus 13 (2003) 791-800
30. Yasuhara T., Shingo T., Kobayashi K., Takeuchi A., Yano A., Muraoka K., Matsui T., Miyoshi Y., Hamada H., and Date I. Neuroprotective effects of vascular endothelial growth factor (VEGF) upon dopaminergic neurons in a rat model of Parkinson's disease. Eur. J. Neurosci. 19 (2004) 1494-1504
31. Yukie M., Yamaguchi K., and Yamashima T. Impairments in recognition memory for object and for location after transient brain ischemia in monkeys. Rev. Neurosci. 17 (2006) 201-214
32. Zola-Morgan S., Squire L.R., and Amaral D.G. Human amnesia and the medial temporal region: enduring memory impairment following a bilateral lesion limited to field CA1 of the hippocampus. J. Neurosci. 6 (1986) 2950-2967
33. Zola-Morgan S., Squire L.R., Rempel N.L., Clower R.P., and Amaral D.G. Enduring memory impairment in monkeys after ischemic damage to the hippocampus. J. Neurosci. 12 (1992) 2582-2596