Evaluation of antimycobacterial and DNA gyrase inhibition of fluoroquinolone derivatives

Journal of General and Applied Microbiology

Volumn 52, Issue 4, 2006, Pages 195-200

  Sriram, Dharmarajan ^a   Bal, Tanushree Ratan ^a   Yogeeswari, Perumal ^a   Radha, Deshpande R ^b   Nagaraja, Valakunja ^b  

^a BIRLA INSTITUTE OF TECHNOLOGY AND SCIENCE   (India)

^b INDIAN INSTITUTE OF SCIENCE   (India)

Author keywords

DNA gyrase inhibition; Fluoroquinolone derivatives; Isatin derivatives; Mycobacterium smegmatis; Mycobacterium tuberculosis

Indexed keywords

CIPROFLOXACIN; DNA TOPOISOMERASE (ATP HYDROLYSING); ETHAMBUTOL; ETHIONAMIDE; ISONIAZID; KANAMYCIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT; RIFAMPICIN; ANTIINFECTIVE AGENT; QUINOLONE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBACTERIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG POTENCY; DRUG RESPONSE; DRUG SCREENING; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LUNG TUBERCULOSIS; MINIMUM INHIBITORY CONCENTRATION; MOUSE; MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; SINGLE DRUG DOSE; STRUCTURE ANALYSIS; ANIMAL; CERCOPITHECUS; CHEMICAL STRUCTURE; DRUG ANTAGONISM; DRUG EFFECT; MICROBIOLOGICAL EXAMINATION; VERO CELL;

BACTERIA (MICROORGANISMS); MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS;

ANIMALS; ANTI-BACTERIAL AGENTS; CERCOPITHECUS AETHIOPS; DNA GYRASE; FLUOROQUINOLONES; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS; VERO CELLS;

EID: 34547507242     PISSN: 00221260     EISSN: 13498037     Source Type: Journal    
DOI: 10.2323/jgam.52.195     Document Type: Article

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