Body composition: An important determinant of homocysteine and methionine concentrations in healthy individuals

Nutrition, Metabolism and Cardiovascular Diseases

Volumn 17, Issue 7, 2007, Pages 525-534

  Battezzati, Alberto ^a   Bertoli, Simona ^a   San Romerio, Antonella ^a   Testolin, Giulio ^a  

^a UNIVERSITY OF MILAN   (Italy)

Author keywords

Body composition; Folates; Homocysteine; Lean body mass; Methionine

Indexed keywords

CYANOCOBALAMIN; FOLIC ACID; HOMOCYSTEINE; METHIONINE; PYRIDOXINE; VITAMIN B COMPLEX;

ADIPOSE TISSUE; ADULT; ARTICLE; BLOOD; BODY COMPOSITION; BODY WATER; FEMALE; HUMAN; HYPERHOMOCYSTEINEMIA; LIFESTYLE; MALE; MENOPAUSE; METABOLISM; MIDDLE AGED; PHYSIOLOGY; RISK FACTOR; SEX DIFFERENCE; SKELETAL MUSCLE;

ADIPOSE TISSUE; ADULT; BODY COMPOSITION; BODY WATER; FEMALE; FOLIC ACID; HOMOCYSTEINE; HUMANS; HYPERHOMOCYSTEINEMIA; LIFE STYLE; MALE; MENOPAUSE; METHIONINE; MIDDLE AGED; MUSCLE, SKELETAL; RISK FACTORS; SEX FACTORS; VITAMIN B 12; VITAMIN B 6; VITAMIN B COMPLEX;

EID: 34547490131     PISSN: 09394753     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.numecd.2006.03.006     Document Type: Article

References (41)

1. Clarke R., Daly L., Robinson K., et al. Hyperhomocysteinemia: an independent risk factor for vascular disease. N Engl J Med 324 (1991) 1149
2. Homocysteine Studies Collaboration. Homocysteine and risk of ischemic heart disease and stroke: a meta-analysis. JAMA 288 (2002) 2015
3. Mc Cully K.S., and Wilson R.B. Homocysteine theory of arteriosclerosis. Arteriosclerosis 22 (1975) 215
4. Mc Cully K.S. Vascular pathology of homocysteinemia: implication for the pathogenesis of arteriosclerosis. Am J Pathol 56 (1969) 111
5. Ueland P.M., and Refsum H. Plasma homocysteine, a risk factor for vascular disease: plasma levels in health, disease, and drug therapy. J Lab Clin Med 114 (1989) 473
6. Wilcken D.E.L., and Wilcken B. The pathogenesis of coronary artery disease. A possible role for methionine metabolism. J Clin Invest 57 (1976) 1079
7. Seshadri S., Beiser A., Selhub J., et al. Plasma homocysteine as a risk factor for dementia and Alzheimer's disease. New Engl J Med 346 (2002) 476
8. Blom H.J. Genetic determinants of hyperhomocysteinaemia: the roles of cystathionine beta-synthase and 5,10-methylenetetrahydrofolate reductase. Eur J Pediatr 159 (2000) S208
9. Dalery K., Lussier-Cacan S., Selhub J., Davignon J., Latour Y., and Genest Jr. J. Homocysteine and coronary artery disease in French Canadian subjects: relationship with vitamin B12, B6, pyridoxal phosphate and folate. Am J Cardiol 75 (1995) 1107
10. Jacques P.F., Bostom A.G., Wilson P.W., Rich S., Rosenberg I.H., and Selhub J. Determinants of plasma total homocysteine concentration in the Framingham Offspring cohort. Am J Clin Nutr 73 (2001) 613
11. Quinlivan E.P., McPartlin J., McNulty H., et al. Importance of both folic acid and vitamin B12 in reduction of risk of vascular disease. Lancet 359 (2002) 227
12. Ubbink J.B., Vermaak W.J., van der Merwe A., and Becker P.J. Vitamin B12, vitamin B6, and folate nutritional status in men with hyperhomocysteinemia. Am J Clin Nutr 57 (1993) 47
13. Valera-Moreiras G. Nutritional regulation of homocysteine: effects of drugs. Biomed Pharmacother 55 (2001) 448
14. Bailey L.B., and Gregory III J.F. Polymorphisms of methylenetetrahydrofolate reductase and other enzymes: metabolic significance, risks and impact on folate requirement. J Nutr 129 (1999) 919-922
15. Strain J.J., Dowey L., Ward M., Pentieva K., and McNulty H. B-vitamins, homocysteine metabolism and CVD. Proc Nutr Soc. 63 (2004) 597-603
16. Andersson A., Brattstrom L., Israelsson B., Isaksson A., Hamfelt A., and Hultberg B. Plasma homocysteine before and after methionine loading with regard to age, gender, and menopausal status. Eur J Clin Invest 22 (1992) 79
17. Garg U.C. Short-term and long-term variability of plasma homocysteine measurements. Clin Chem 43 (1997) 141
18. Mudd S.H., and Poole J.R. Labile methyl balances for normal humans on various dietary regimens. Metabolism 24 (1975) 721
19. Dierkes J., Jeckel A., Ambrosch A., Westphal S., Luley C., and Boeing H. Factors explaining the difference of total homocysteine between men and women in the European Investigation In Cancer and Nutrition Potsdam study. Metabolism 50 (2001) 640
20. Rauh M., Verwied S., Knerr I., Dorr H.G., Sonnichsen A., and Koletzko B. Homocysteine concentrations in a German cohort of 500 individuals: reference ranges and determinants of plasma levels in healthy children and their parents. Amino Acids 20 (2001) 409
21. Fors H., Gelander L., Bjarnason R., Albertsson-Wikland K., and Bosaeus I. Body composition, as assessed by bioelectrical impedance spectroscopy and dual-energy X-ray absorptiometry, in a healthy paediatric population. Acta Paediatr 91 (2002) 755
22. Zamboni M., Di Francesco V., Zoico E., et al. Homocysteine and life-style in the elderly. Aging 13 (2001) 437
23. Fukagawa N.K., Martin J.M., Wurthmann A., Prue A.H., Ebenstein D., and O'Rourke B. Sex-related differences in methionine metabolism and plasma homocysteine concentration. Am J Clin Nutr 72 (2000) 22
24. Ingenbleek Y., Hardillier E., and Jung L. Subclinical protein malnutrition is a determinant of hyperhomocysteinemia. Nutrition 18 (2002) 40-46
25. Ingenbleek Y., and Young V.R. The essentiality of sulfur is closely related to nitrogen metabolism: a clue to hyperhomocysteinaemia. Nutr Res Rev 17 2 (2004) 135-151
26. Lohman T.G., Roche A.F., and Martorel R. Anthropometric Standardization Reference Manual (1988), Human Kinetics Books, Champagne, IL
27. Durnin J.V., and Womersley J. Body fat assessment from total body density and its estimation from skinfold thickness: measurements on 481 men and women aged from 16 to 72 years. BR J Nutr 32 (1974) 77
28. Siri W.E. Body composition from fluid spaces and density: analysis of methods. In: Broken J., and Hanschel A. (Eds). Techniques for Measuring Body Composition. (1961), National Academy of Science, Washington DC 223
29. Ley C.J., Lees B., and Stevenson J.C. Sex- and menopause-associated changes in body-fat distribution. Am J Clin Nutr 55 (1992) 950
30. Segal K.R., Burastero S., Chun A., Coronel P., Pierson Jr. R.N., and Wang J. Estimation of extracellular and total body water by multiple-frequency bioelectrical-impedance measurement. Am J Clin Nutr 54 (1991) 26
31. Deurenberg P., Van der Kooy K., Leenen R., Weststrate J.A., and Seidell J.C. Sex and age specific prediction formulas for estimating body composition from bioelectrical impedance: a cross-validation study. Int J Obes 15 (1991) 17
32. Battezzati A., Benedini S., Fattorini A., et al. Insulin action on protein metabolism in acromegalic patients. Am J Physiol Endocrinol Metab 284 (2003) E823
33. Fermo I., Arcelloni C., Mazzola G., D'Angelo A., and Paroni R. High-performance liquid chromatographic method for measuring total plasma homocysteine levels. J Chromatogr Biomed Sci Appl 719 (1998) 31
34. Bates C.J., Pentieva K.D., Matthews N., and Macdonald A. A simple, sensitive and reproducible assay for pyridoxal 5′-phosphate and 4-pyridoxic acid in human plasma. Clin Chim Acta 280 (1999) 101
35. Volpi E., Lucidi P., Bolli G.B., Santeusanio F., and De Feo P. Gender differences in basal protein kinetics in young adults. J Clin Endocrinol Metab 83 (1998) 4363
36. Stead L.M., Au K.P., Jacobs R.L., Brosnan M.E., and Brosnan J.T. Methylation demand and homocysteine metabolism: effects of dietary provision of creatine and guanidinoacetate. Am J Physiol Endocrinol Metab 281 (2001) E1095
37. Spate U., and Schulze P.C. Proinflammatory cytokines and skeletal muscle. Curr Opin Clin Nutr Metab Care 7 3 (2004 May) 265-269
38. McFarlane S.I., Muniyappa R., Shin J.J., Bahtiyar G., and Sowers J.R. Osteoporosis and cardiovascular disease: brittle bones and boned arteries, is there a link?. Endocrine 23 1 (2004 Feb) 1-10
39. Welch G.N., and Loscalzo J. Homocysteine and atherothrombosis. N Engl J Med 338 (1998) 1042-1050
40. Outinen P.A., Sood S.K., Pfeifer S.I., et al. Homocysteine-induced endoplasmic reticulum stress and growth arrest leads to specific changes in gene expression in human vascular endothelial cells. Blood 94 (1999) 959-967
41. Pruefer D., Scalia R., and Lefer A.M. Homocysteine provokes leukocyte-endothelium interaction by down regulation of nitric oxide. Gen Pharmacol 33 (1999) 487-498