메뉴 건너뛰기




Volumn 27, Issue 8, 2007, Pages 1181-1188

Sugammadex: A novel agent for the reversal of neuromuscular blockade

Author keywords

Cholinesterase inhibitor; Cyclodextrin; Org 25969; Rocuronium; Sugammadex

Indexed keywords

ATRACURIUM; ATROPINE; CHOLINERGIC RECEPTOR BLOCKING AGENT; CHOLINESTERASE INHIBITOR; CISATRACURIUM; DOXACURIUM; GAMMA CYCLODEXTRIN; GLYCOPYRRONIUM BROMIDE; NEOSTIGMINE; NEUROMUSCULAR BLOCKING AGENT; PANCURONIUM; ROCURONIUM; SUGAMMADEX; SUXAMETHONIUM; VECURONIUM;

EID: 34547477926     PISSN: 02770008     EISSN: None     Source Type: Journal    
DOI: 10.1592/phco.27.8.1181     Document Type: Review
Times cited : (47)

References (46)
  • 1
    • 0035170614 scopus 로고    scopus 로고
    • Structure, conformation, and action of neuromuscular blocking drugs
    • Lee C. Structure, conformation, and action of neuromuscular blocking drugs. Br J Anaesth 2001;87:755-69.
    • (2001) Br J Anaesth , vol.87 , pp. 755-769
    • Lee, C.1
  • 2
    • 0017336108 scopus 로고
    • Suxamethonium-neostigmine interaction in patients with normal or atypical cholinesterase
    • Baraka A. Suxamethonium-neostigmine interaction in patients with normal or atypical cholinesterase. Br J Anaesth 1977;49:479-84.
    • (1977) Br J Anaesth , vol.49 , pp. 479-484
    • Baraka, A.1
  • 3
    • 4344606162 scopus 로고    scopus 로고
    • Physicochemical properties of neuromuscular blocking agents and their impact on the pharmacokinetic-pharmacodynamic relationship
    • Roy JJ, Varin F. Physicochemical properties of neuromuscular blocking agents and their impact on the pharmacokinetic-pharmacodynamic relationship. Br J Anaesth 2004;93:241-8.
    • (2004) Br J Anaesth , vol.93 , pp. 241-248
    • Roy, J.J.1    Varin, F.2
  • 4
    • 0033152188 scopus 로고    scopus 로고
    • Monitoring and reversal of neuromuscular block
    • Bevan DR. Monitoring and reversal of neuromuscular block. AmJ Health-Syst Pharm 1999;56:S10-13.
    • (1999) AmJ Health-Syst Pharm , vol.56
    • Bevan, D.R.1
  • 5
    • 0037147765 scopus 로고    scopus 로고
    • Oxyaniliniums as acetylcholinesterase inhibitors for the reversal of neuromuscular block
    • Grove SJ, Kaur J, Muir AW, Pow E, Tarver GJ, Zhang MQ. Oxyaniliniums as acetylcholinesterase inhibitors for the reversal of neuromuscular block. Bioorg Med Chem Lett 2002;12:193-6.
    • (2002) Bioorg Med Chem Lett , vol.12 , pp. 193-196
    • Grove, S.J.1    Kaur, J.2    Muir, A.W.3    Pow, E.4    Tarver, G.J.5    Zhang, M.Q.6
  • 6
    • 0031409223 scopus 로고    scopus 로고
    • Stein RD, Backman SB, Collier B, Polosa C. Bradycardia produced by pyridostigmine and physostigmine. Can J Anaesth 1997;44:1286-92. (Erratum in Can J Anaesth 1998;45:382.)
    • Stein RD, Backman SB, Collier B, Polosa C. Bradycardia produced by pyridostigmine and physostigmine. Can J Anaesth 1997;44:1286-92. (Erratum in Can J Anaesth 1998;45:382.)
  • 7
    • 0029994105 scopus 로고    scopus 로고
    • Neostigmine-induced bradycardia following recent vs remote cardiac transplantation in the same patient
    • Backman SB, Stein RD, Ralley FE, Fox GS. Neostigmine-induced bradycardia following recent vs remote cardiac transplantation in the same patient. Can J Anaesth 1996;43:394-8.
    • (1996) Can J Anaesth , vol.43 , pp. 394-398
    • Backman, S.B.1    Stein, R.D.2    Ralley, F.E.3    Fox, G.S.4
  • 9
    • 0031740286 scopus 로고    scopus 로고
    • Neostigmine with glycopyrrolate does not increase the incidence or severity of postoperative nausea and vomiting in outpatients undergoing gynaecological laparoscopy
    • Nelskyla K, Yli-Hankala A, Soikkeli A, Korttila K. Neostigmine with glycopyrrolate does not increase the incidence or severity of postoperative nausea and vomiting in outpatients undergoing gynaecological laparoscopy. Br J Anaesth 1998;81:757-60.
    • (1998) Br J Anaesth , vol.81 , pp. 757-760
    • Nelskyla, K.1    Yli-Hankala, A.2    Soikkeli, A.3    Korttila, K.4
  • 10
    • 27444446152 scopus 로고    scopus 로고
    • Does neostigmine administration produce a clinically important increase in postoperative nausea and vomiting?
    • Cheng CR, Sessler DI, Apfel CC. Does neostigmine administration produce a clinically important increase in postoperative nausea and vomiting? Anesth Analg 2005;101:1349-55.
    • (2005) Anesth Analg , vol.101 , pp. 1349-1355
    • Cheng, C.R.1    Sessler, D.I.2    Apfel, C.C.3
  • 11
    • 0033065137 scopus 로고    scopus 로고
    • Omitting antagonism of neuromuscular block: Effect on postoperative nausea and vomiting and risk of residual paralysis. A systematic review
    • Tramer MR, Fuchs-Buder T. Omitting antagonism of neuromuscular block: effect on postoperative nausea and vomiting and risk of residual paralysis. A systematic review. Br J Anaesth 1999;82:379-86.
    • (1999) Br J Anaesth , vol.82 , pp. 379-386
    • Tramer, M.R.1    Fuchs-Buder, T.2
  • 12
    • 0031407956 scopus 로고    scopus 로고
    • Reversal of neuromuscular blockade with neostigmine has no effect on the incidence or severity of postoperative nausea and vomiting
    • Hovorka J, Korttila K, Nelskyla K, et al. Reversal of neuromuscular blockade with neostigmine has no effect on the incidence or severity of postoperative nausea and vomiting. Anesth Analg 1997;85:1359-61.
    • (1997) Anesth Analg , vol.85 , pp. 1359-1361
    • Hovorka, J.1    Korttila, K.2    Nelskyla, K.3
  • 13
    • 85088085776 scopus 로고
    • Does neostigmine cause nausea and vomiting? [comment]
    • Boeke AJ. Does neostigmine cause nausea and vomiting? [comment] Anesth Analg 1995;80:849.
    • (1995) Anesth Analg , vol.80 , pp. 849
    • Boeke, A.J.1
  • 14
    • 0028271654 scopus 로고
    • Use of mivacurium during laparoscopic surgery: Effect of reversal drugs on postoperative recovery
    • Ding Y, Fredman B, White PF. Use of mivacurium during laparoscopic surgery: effect of reversal drugs on postoperative recovery. Anesth Analg 1994;78:450-4.
    • (1994) Anesth Analg , vol.78 , pp. 450-454
    • Ding, Y.1    Fredman, B.2    White, P.F.3
  • 15
    • 18044401495 scopus 로고    scopus 로고
    • Neostigmine 50 microg kg(-1) with glycopyrrolate increases postoperative nausea in women after laparoscopic gynaecological surgery
    • Lovstad RZ, Thagaard KS, Berner NS, Raeder JC. Neostigmine 50 microg kg(-1) with glycopyrrolate increases postoperative nausea in women after laparoscopic gynaecological surgery. Acta Anaesthesiol Scand 2001;45:495-500.
    • (2001) Acta Anaesthesiol Scand , vol.45 , pp. 495-500
    • Lovstad, R.Z.1    Thagaard, K.S.2    Berner, N.S.3    Raeder, J.C.4
  • 16
    • 0021929704 scopus 로고
    • Antagonism of neuromuscular block in the elderly: A comparison of atropine and glycopyrronium in a mixture with neostigmine
    • Mirakhur RK. Antagonism of neuromuscular block in the elderly: a comparison of atropine and glycopyrronium in a mixture with neostigmine. Anaesthesia 1985;40:254-8.
    • (1985) Anaesthesia , vol.40 , pp. 254-258
    • Mirakhur, R.K.1
  • 17
    • 0018373937 scopus 로고
    • Atropine-induced ventricular fibrillation: Case report and review of the literature
    • Cooper MJ, Abinader EG. Atropine-induced ventricular fibrillation: case report and review of the literature. Am Heart J 1979;97:225-8.
    • (1979) Am Heart J , vol.97 , pp. 225-228
    • Cooper, M.J.1    Abinader, E.G.2
  • 18
    • 0033082254 scopus 로고    scopus 로고
    • The effect of ammonium glycopyrrolate (Robinul)-induced xerostomia on oral mucosal wetness and flow of gingival crevicular fluid in humans
    • Wolff MS, Weinberg I. The effect of ammonium glycopyrrolate (Robinul)-induced xerostomia on oral mucosal wetness and flow of gingival crevicular fluid in humans. Arch Oral Biol 1999;44:97-102.
    • (1999) Arch Oral Biol , vol.44 , pp. 97-102
    • Wolff, M.S.1    Weinberg, I.2
  • 20
    • 26244449246 scopus 로고    scopus 로고
    • First human exposure of Org 25969, a novel agent to reverse the action of rocuronium bromide
    • Gijsenbergh F, Ramael S, Houwing N, van Iersel T. First human exposure of Org 25969, a novel agent to reverse the action of rocuronium bromide. Anesthesiology 2005;103:695-703.
    • (2005) Anesthesiology , vol.103 , pp. 695-703
    • Gijsenbergh, F.1    Ramael, S.2    Houwing, N.3    van Iersel, T.4
  • 21
    • 15944387415 scopus 로고    scopus 로고
    • Dose-response relationship of rocuronium: A comparison of electromyographic vs. acceleromyographic-derived values
    • Kopman AF, Chin WA, Moe J. Dose-response relationship of rocuronium: a comparison of electromyographic vs. acceleromyographic-derived values. Acta Anaesthesiol Scand 2005;49:323-7.
    • (2005) Acta Anaesthesiol Scand , vol.49 , pp. 323-327
    • Kopman, A.F.1    Chin, W.A.2    Moe, J.3
  • 22
    • 0037406756 scopus 로고    scopus 로고
    • Evidence-based practice and neuromuscular monitoring: It's time for routine quantitative assessment
    • Eriksson LI. Evidence-based practice and neuromuscular monitoring: it's time for routine quantitative assessment. Anesthesiology 2003;98:1037-9.
    • (2003) Anesthesiology , vol.98 , pp. 1037-1039
    • Eriksson, L.I.1
  • 23
    • 0035232930 scopus 로고    scopus 로고
    • Use of reversal agents in day care procedures (with special reference to postoperative nausea and vomiting)
    • Fuchs-Buder F, Mencke F. Use of reversal agents in day care procedures (with special reference to postoperative nausea and vomiting). Eur J Anaesthesiol 2001;23(suppl):53-9.
    • (2001) Eur J Anaesthesiol , vol.23 , Issue.SUPPL. , pp. 53-59
    • Fuchs-Buder, F.1    Mencke, F.2
  • 24
    • 0037407606 scopus 로고    scopus 로고
    • Residual paralysis in the PACU after a single intubating dose of nondepolarizing muscle relaxant with an intermediate duration of action
    • Debaene B, Plaud B, Dilly MP, Donati F. Residual paralysis in the PACU after a single intubating dose of nondepolarizing muscle relaxant with an intermediate duration of action. Anesthesiology 2003;98:1042-8.
    • (2003) Anesthesiology , vol.98 , pp. 1042-1048
    • Debaene, B.1    Plaud, B.2    Dilly, M.P.3    Donati, F.4
  • 25
    • 0015073869 scopus 로고
    • Clinical neuromuscular pharmacology of pancuronium
    • Katz RL. Clinical neuromuscular pharmacology of pancuronium. Anesthesiology 1971;34:550-6.
    • (1971) Anesthesiology , vol.34 , pp. 550-556
    • Katz, R.L.1
  • 27
    • 0023219769 scopus 로고
    • Incomplete reversal of pancuronium neuromuscular blockade by neostigmine, pyridostigmine, and edrophonium
    • Bartkowski RR. Incomplete reversal of pancuronium neuromuscular blockade by neostigmine, pyridostigmine, and edrophonium. Anesth Analg 1987;66:594-8.
    • (1987) Anesth Analg , vol.66 , pp. 594-598
    • Bartkowski, R.R.1
  • 28
    • 33845573098 scopus 로고    scopus 로고
    • Cyclodextrins and their pharmaceutical applications
    • Loftsson T, Duchene D. Cyclodextrins and their pharmaceutical applications. Int J Pharm 2007;329:1-11.
    • (2007) Int J Pharm , vol.329 , pp. 1-11
    • Loftsson, T.1    Duchene, D.2
  • 29
    • 0029819323 scopus 로고    scopus 로고
    • Pharmaceutical applications of cyclodextrins. 1. Drug solubilization and stabilization
    • Loftsson T, Brewster ME. Pharmaceutical applications of cyclodextrins. 1. Drug solubilization and stabilization. J Pharm Sci 1996;85:1017-25.
    • (1996) J Pharm Sci , vol.85 , pp. 1017-1025
    • Loftsson, T.1    Brewster, M.E.2
  • 30
    • 0036182021 scopus 로고    scopus 로고
    • The use of chemically modified cyclodextrins in the development of formulations for chemical delivery systems
    • Brewster ME, Loftsson T. The use of chemically modified cyclodextrins in the development of formulations for chemical delivery systems. Pharmazie 2002;57:94-101.
    • (2002) Pharmazie , vol.57 , pp. 94-101
    • Brewster, M.E.1    Loftsson, T.2
  • 31
    • 0035964466 scopus 로고    scopus 로고
    • Cyclodextrins in topical drug formulations: Theory and practice
    • Loftsson T, Masson M. Cyclodextrins in topical drug formulations: theory and practice. Int J Pharm 2001;225:15-30.
    • (2001) Int J Pharm , vol.225 , pp. 15-30
    • Loftsson, T.1    Masson, M.2
  • 32
    • 0037764893 scopus 로고    scopus 로고
    • Inclusion complexes of ketosteroids with beta-cyclodextrin
    • Forgo P, Vincze I, Kover KE. Inclusion complexes of ketosteroids with beta-cyclodextrin. Steroids 2003;68:321-7.
    • (2003) Steroids , vol.68 , pp. 321-327
    • Forgo, P.1    Vincze, I.2    Kover, K.E.3
  • 33
    • 0036117863 scopus 로고    scopus 로고
    • Cyclodextrins in eye drop formulations: Enhanced topical delivery of corticosteroids to the eye
    • Loftsson T, Stefansson E. Cyclodextrins in eye drop formulations: enhanced topical delivery of corticosteroids to the eye. Acta Ophthalmol Scand 2002;80:144-50.
    • (2002) Acta Ophthalmol Scand , vol.80 , pp. 144-150
    • Loftsson, T.1    Stefansson, E.2
  • 34
    • 0034672285 scopus 로고    scopus 로고
    • Characterization of inclusion complexes of betamethasone-related steroids with cyclodextrins using high-performance liquid chromatography
    • Flood KG, Reynolds ER, Snow NH. Characterization of inclusion complexes of betamethasone-related steroids with cyclodextrins using high-performance liquid chromatography. J Chromatog A 2000;903:49-65.
    • (2000) J Chromatog A , vol.903 , pp. 49-65
    • Flood, K.G.1    Reynolds, E.R.2    Snow, N.H.3
  • 35
    • 3242665113 scopus 로고    scopus 로고
    • Cyclodextrins: Preface
    • Bar A. Cyclodextrins: preface. Regul Toxicol Pharmacol 2004;39(suppl 1):S1-2.
    • (2004) Regul Toxicol Pharmacol , vol.39 , Issue.SUPPL. 1
    • Bar, A.1
  • 36
    • 0037171790 scopus 로고    scopus 로고
    • Cyclodextrin-derived host molecules as reversal agents for the neuromuscular blocker rocuronium bromide: Synthesis and structure-activity relationships
    • Adam JM, Bennett DJ, Bom A, et al. Cyclodextrin-derived host molecules as reversal agents for the neuromuscular blocker rocuronium bromide: synthesis and structure-activity relationships. J Med Chem 2002;45:1806-16.
    • (2002) J Med Chem , vol.45 , pp. 1806-1816
    • Adam, J.M.1    Bennett, D.J.2    Bom, A.3
  • 37
    • 0037127108 scopus 로고    scopus 로고
    • A novel concept of reversing neuromuscular block: Chemical encapsulation of rocuronium bromide by a cyclodextrin-based synthetic host
    • Bom A, Bradley M, Cameron K, et al. A novel concept of reversing neuromuscular block: chemical encapsulation of rocuronium bromide by a cyclodextrin-based synthetic host. Angewandte Chemie, international ed 2002;41:266-70.
    • (2002) Angewandte Chemie, international ed , vol.41 , pp. 266-270
    • Bom, A.1    Bradley, M.2    Cameron, K.3
  • 38
    • 33747372242 scopus 로고    scopus 로고
    • The doughnut and the hole: A new pharmacological concept for anaesthetists
    • Hunter JM, Flockton EA. The doughnut and the hole: a new pharmacological concept for anaesthetists. Br J Anaesth 2006;97:123-6.
    • (2006) Br J Anaesth , vol.97 , pp. 123-126
    • Hunter, J.M.1    Flockton, E.A.2
  • 39
    • 33645638903 scopus 로고    scopus 로고
    • Sugammadex: A revolutionary approach to neuromuscular antagonism
    • Kopman AF. Sugammadex: a revolutionary approach to neuromuscular antagonism. Anesthesiology 2006;104:631-3.
    • (2006) Anesthesiology , vol.104 , pp. 631-633
    • Kopman, A.F.1
  • 40
    • 0036009879 scopus 로고    scopus 로고
    • 2-O-substituted cyclodextrins as reversal agents for the neuromuscular blocker rocuronium bromide
    • Tarver GJ, Grove SJ, Buchanan K, et al. 2-O-substituted cyclodextrins as reversal agents for the neuromuscular blocker rocuronium bromide. Bioorg Med Chem 2002;10:1819-27.
    • (2002) Bioorg Med Chem , vol.10 , pp. 1819-1827
    • Tarver, G.J.1    Grove, S.J.2    Buchanan, K.3
  • 41
    • 33645289950 scopus 로고    scopus 로고
    • Sugammadex, a new reversal agent for neuromuscular block induced by rocuronium in the anaesthetized rhesus monkey
    • de Boer HD, van Egmond J, van de Pol F, Bom A, Booij LH. Sugammadex, a new reversal agent for neuromuscular block induced by rocuronium in the anaesthetized rhesus monkey. Br J Anaesth 2006;96:473-9.
    • (2006) Br J Anaesth , vol.96 , pp. 473-479
    • de Boer, H.D.1    van Egmond, J.2    van de Pol, F.3    Bom, A.4    Booij, L.H.5
  • 42
    • 0036388228 scopus 로고    scopus 로고
    • Liquid chromatography/mass spectrometric bioanalysis of a modified γ-cyclodextrin (Org 25969) and rocuronium bromide (Org 9426) in guinea pig plasma and urine: Its application to determine the plasma pharmacokinetics of Org 25969
    • Epemolu O, Mayer I, Hope F, Scullion P, Desmond P. Liquid chromatography/mass spectrometric bioanalysis of a modified γ-cyclodextrin (Org 25969) and rocuronium bromide (Org 9426) in guinea pig plasma and urine: its application to determine the plasma pharmacokinetics of Org 25969. Rapid Commun Mass Spectrom 2002;16:1946-52.
    • (2002) Rapid Commun Mass Spectrom , vol.16 , pp. 1946-1952
    • Epemolu, O.1    Mayer, I.2    Hope, F.3    Scullion, P.4    Desmond, P.5
  • 43
    • 33645639158 scopus 로고    scopus 로고
    • Rapid reversal of rocuronium-induced neuromuscular block by Org 25969 is independent of renal perfusion [abstract]
    • Bom A, van Egmond J, Hope F, van de Pol F. Rapid reversal of rocuronium-induced neuromuscular block by Org 25969 is independent of renal perfusion [abstract]. Anesthesiology 2003;99:A1158.
    • (2003) Anesthesiology , vol.99
    • Bom, A.1    van Egmond, J.2    Hope, F.3    van de Pol, F.4
  • 44
    • 0041324616 scopus 로고    scopus 로고
    • Reversal of neuromuscular blockade and simultaneous increase in plasma rocuronium concentration after the intravenous infusion of the novel reversal agent Org 25969
    • Epemolu O, Bom A, Hope F, Mason R. Reversal of neuromuscular blockade and simultaneous increase in plasma rocuronium concentration after the intravenous infusion of the novel reversal agent Org 25969. Anesthesiology 2003;99:632-7.
    • (2003) Anesthesiology , vol.99 , pp. 632-637
    • Epemolu, O.1    Bom, A.2    Hope, F.3    Mason, R.4
  • 45
    • 33645646481 scopus 로고    scopus 로고
    • Reversal of rocuronium-induced neuromuscular block by the selective relaxant binding agent sugammadex: A dose-finding and safety study
    • Sorgenfrei IF, Norrild K, Larsen PB, et al. Reversal of rocuronium-induced neuromuscular block by the selective relaxant binding agent sugammadex: a dose-finding and safety study. Anesthesiology 2006;104:667-74.
    • (2006) Anesthesiology , vol.104 , pp. 667-674
    • Sorgenfrei, I.F.1    Norrild, K.2    Larsen, P.B.3
  • 46
    • 31144448393 scopus 로고    scopus 로고
    • Org 25969 (sugammadex), a selective relaxant binding agent for antagonism of prolonged rocuronium-induced neuromuscular block
    • Shields M, Giovannelli M, Mirakhur RK, Moppett I, Adams J, Hermens Y. Org 25969 (sugammadex), a selective relaxant binding agent for antagonism of prolonged rocuronium-induced neuromuscular block. Br J Anaesth 2006;96:36-43.
    • (2006) Br J Anaesth , vol.96 , pp. 36-43
    • Shields, M.1    Giovannelli, M.2    Mirakhur, R.K.3    Moppett, I.4    Adams, J.5    Hermens, Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.