Ozone administration reduces reperfusion injury in an isolated rat heart model

Journal of Cardiac Surgery

Volumn 22, Issue 4, 2007, Pages 339-342

  Merin, Ofer ^a   Attias, Eyal ^b   Elstein, Deborah ^a   Schwalb, Herzl ^c   Bitran, Dani ^a   Zimran, Ari ^a   Silberman, Shuli ^a  

^a SHAARE ZEDEK MEDICAL CENTER   (Israel)

^b Ma'ayaney Hayeshua Medical Center   (Israel)

^c HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

BUFFER; KREBS HENSELEIT BUFFER; OZONE; UNCLASSIFIED DRUG; WATER;

ANIMAL TISSUE; ARTERY CATHETERIZATION; ARTICLE; ASCENDING AORTA; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; HEART; HEART LEFT VENTRICLE PRESSURE; HEART RATE; HEMODYNAMICS; ISCHEMIA; NONHUMAN; RAT; REPERFUSION INJURY;

ANIMALS; CARDIAC OUTPUT; CORONARY CIRCULATION; GLUCOSE; HEART RATE; MYOCARDIAL CONTRACTION; MYOCARDIAL REPERFUSION INJURY; OZONE; RATS; RATS, SPRAGUE-DAWLEY; RECOVERY OF FUNCTION; TROMETHAMINE; VENTRICULAR FUNCTION, LEFT;

EID: 34547472045     PISSN: 08860440     EISSN: 15408191     Source Type: Journal    
DOI: 10.1111/j.1540-8191.2007.00419.x     Document Type: Article

References (28)

1. Forman MB, Virmani R, Puett DW : Mechanisms and therapy of myocardial reperfusion injury. Circulation 1990 81 (Suppl IV IV69 IV78.
2. Ambrosio G, Tritto I : Reperfusion injury: experimental evidence and clinical implications. Am Heart J 1999 138 : S69 S75.
3. Braunwald E, Kloner RA : Myocardial reperfusion: A double-edged sword? J Clin Invest 1985 76 : 1713 1719.
4. Fujino Y, Suzuki Y, Kahinoki K, et al : Protection against experimental small intestinal ischeamia-reperfusion injury with oxygenated perfluorochemical. Br Surg 2003 90 : 1015 1020.
5. Claeys MJ, Bosmans J, De Ceuninck M, et al : Effect of intracoronary adenosine infusion during coronary intervention on myocardial reperfusion injury in patients with acute myocardial infarction. Am J Cardiol 2004 94 : 9 13.
6. Murohara Y, Yui Y, Hattori R, et al : Effects of superoxide dismutase on reperfusion arrythmias and left ventricular function in patients undergoing thrombolysis for anterior wall acute myocardial infarction. Am J Cardiol 1991 67 : 765 767.
7. Beck EG, Viebahn-Hansler J : Ozone Handbook. Grund-werk Publications, Germany, 1995.
8. Komanapalli IR, Lau BH : Inactivation of bacteriophage lambda, Escherichia coli, and Candida albicans by ozone. Appl Microbiol 1998 49 : 766 769.
9. Bocci V : Ozone as Janus: this controversial gas can be either toxic or medically useful. Mediators Inflamm 2004 13 : 3 11.
10. Romero Valdes A, Blanco Gonzales R, et al : Arteiosclerosis obliterans and ozone therapy. Its administration by different routes. Angiologia 1993 45 : 177 179.
11. NIH publication no. 86-23, revised 1985.
12. Van Der Vliet A, O'Neil CA, Eiserich JP, et al : Oxidative damage to extracellular fluids by ozone and possible effects of thiols. Arch Biochem Biophys 1995 321 : 43 50.
13. Bocci V : Autohaemotherapy after treatment of blood with ozone. A reappraisal. J Int Med Res 1994 22 : 131 144.
14. Sroczynski J, Antoszewski Z, Matyszczyk B, et al : Clinical assessment of treatment results for atherosclerotic ischemia of the lower extremities with intraarterial ozone injections. Pol Tyg Lek 1992 47 : 964 966.
15. Peralta C, Xaus C, Bartons R, et al : Effect of ozone treatment on reactive oxygen species and adenosine production during hepatic ischemia-reperfusion. Free Radic Res 2000 33 : 595 605.
16. Ajamieh HH, Berlanga J, Merino N, et al : Role of protein synthesis in the protection conferred by ozone-oxidative-preconditioning in hepatic ischaemia/reperfusion. Transplant Int 2005 18 : 604 612.
17. Kadipasaoglu KA, Bennink GW, Conger JL, et al : An ex vivo model for the reperfusion of explanted human hearts. Tex Heart Inst J 1993 20 : 33 39.
18. Chandra M, Schwalb H, Yaroslavsky-Houminer E, et al : New experimental technique to study blood cardioplegia in the isolated, perfused rat heart. Ann Thorac Surg 1993 55 : 946 949.
19. Tylicki L, Niewglowski T, Biedunkiewicz B, et al : Beneficial clinical effects of ozonated autohemotherapy in chronically dialysed patients with atherosclerotic ischemia of the lower limbs - pilot study. Int J Artif Organs 2001 24 : 79 82.
20. Valacchi G, Bocci V : Studies on the biological effects of ozone: 11. Release of factors from human endothelial cells. Mediators Inflamm 2000 9 : 271 276.
21. Fukuda H, Sawa Y, Kadoba K, et al : Supplement of nitraic oxide attenuates neutrophil-mediated reperfusion injury. Circulation 1995 92 (Suppl II413 II416.
22. Peralta C, Leon OS, Xaus C, et al : Protective effect of ozone treatment on the injury associated with hepatic ischemia-reperfusion: Antioxidant- prooxidant balance. Free Radic Res 1999 31 : 191 196.
23. Ajamieh HH, Menendez S, Martinez-Sanchez G, et al : Effects of ozone oxidative preconditioning on nitric oxide generation and cellular redox balance in a rat model of hepatic ischemia-reperfusion. Liver Int 2004 24 : 55 62.
24. Byvoet P, Balis JU, Shelley SA, et al : Detection of hydroxyl radicals upon interaction of ozone with aqueous media or extracellular surfactant: the role of trace iron. Arch Biochem Biophys 1995 319 : 464 469.
25. Bolli R, Jeroudi MO, Patel BS, et al : Marked reduction of free radical generation and contractile dysfunction by antioxidant therapy begun at the time of reperfusion. Evidence that myocardial "stunning" is a manifestation of reperfusion injury. Circ Res 1989 65 : 607 622.
26. Das DK, Maulik N, Sato M, et al : Reactive oxygen species function as second messenger during ischemic preconditioning of heart. Mol Cell Biochem 1999 196 : 59 67.
27. Zimran A, Wasser G, Forman L, et al : Effect of ozone on red blood cell enzymes and intermediates. Acta Haematol 2000 102 : 148 151.
28. Zimran A, Wasser G, Cherny N, et al : Autohemotherapy with ozone for patients with Gaucher disease and severe skeletal involvement. The Pain Clinic 2001 13 : 223 226.