메뉴 건너뛰기




Volumn 12, Issue 6, 2006, Pages 479-485

Forecasting cholesterol management - End of the statin gold rush?

Author keywords

[No Author keywords available]

Indexed keywords

ATORVASTATIN; C REACTIVE PROTEIN; CERIVASTATIN; COLESTYRAMINE; EZETIMIBE PLUS SIMVASTATIN; FLUINDOSTATIN; GEMFIBROZIL; HIGH DENSITY LIPOPROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LOW DENSITY LIPOPROTEIN; MEVINOLIN; MK 0524; NICOTINIC ACID; NICOTINIC RECEPTOR BLOCKING AGENT; PRAVASTATIN; ROSUVASTATIN; SIMVASTATIN; TORCETRAPIB; UNCLASSIFIED DRUG; GENERIC DRUG; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYPOCHOLESTEROLEMIC AGENT; LOW DENSITY LIPOPROTEIN CHOLESTEROL;

EID: 34547454226     PISSN: 10834087     EISSN: None     Source Type: Journal    
DOI: 10.18553/jmcp.2006.12.6.479     Document Type: Editorial
Times cited : (2)

References (50)
  • 1
    • 85039181757 scopus 로고    scopus 로고
    • Simvastatin (Zocor) [prescribing information from the product label]. Drug Facts and Comparisons (Clinisphere version, ISBN 1-57439-036-8). St. Louis, MO: Wolters, Kluwer Health, Inc.; May 2006. Accessed June 25, 2006.
    • Simvastatin (Zocor) [prescribing information from the product label]. Drug Facts and Comparisons (Clinisphere version, ISBN 1-57439-036-8). St. Louis, MO: Wolters, Kluwer Health, Inc.; May 2006. Accessed June 25, 2006.
  • 2
    • 85039189315 scopus 로고    scopus 로고
    • Lovastatin (Mevacor) [prescribing information from the product label]. Drug Facts and Comparisons (Clinisphere version, ISBN 1-57439-036-8). St. Louis, MO: Wolters, Kluwer Health, Inc.; May 2006. Accessed June 25, 2006.
    • Lovastatin (Mevacor) [prescribing information from the product label]. Drug Facts and Comparisons (Clinisphere version, ISBN 1-57439-036-8). St. Louis, MO: Wolters, Kluwer Health, Inc.; May 2006. Accessed June 25, 2006.
  • 3
    • 0028146792 scopus 로고
    • Expanded Clinical Evaluation of Lovastatin (EXCEL) study results: Two-year efficacy and safety follow-up
    • Bradford RH, Shear CL, Chremos AN, et al. Expanded Clinical Evaluation of Lovastatin (EXCEL) study results: two-year efficacy and safety follow-up. Am J Cardiol. 1994;74(7):667-73.
    • (1994) Am J Cardiol , vol.74 , Issue.7 , pp. 667-673
    • Bradford, R.H.1    Shear, C.L.2    Chremos, A.N.3
  • 4
    • 85039232632 scopus 로고    scopus 로고
    • Atorvastatin calcium (Lipitor) [prescribing information from the product label]. Drug Facts and Comparisons (Clinisphere version, ISBN 1-57439-036-8). St. Louis, MO: Wolters, Kluwer Health, Inc.; June 2006. Accessed July 12, 2006.
    • Atorvastatin calcium (Lipitor) [prescribing information from the product label]. Drug Facts and Comparisons (Clinisphere version, ISBN 1-57439-036-8). St. Louis, MO: Wolters, Kluwer Health, Inc.; June 2006. Accessed July 12, 2006.
  • 6
    • 4344654438 scopus 로고    scopus 로고
    • Top 200 brand drugs by retail dollars in 2002
    • April 7
    • Verispan, Scott-Levin SPA. Top 200 brand drugs by retail dollars in 2002. Drug Top. April 7, 2003:53.
    • (2003) Drug Top , pp. 53
    • Verispan1    Scott-Levin, S.P.A.2
  • 7
    • 85039179912 scopus 로고    scopus 로고
    • Consumer group asks FDA to strengthen warnings on cholesterol lowering drugs
    • August 21
    • Adams C. Consumer group asks FDA to strengthen warnings on cholesterol lowering drugs. Wall Street Journal. August 21, 2001:A2
    • (2001) Wall Street Journal
    • Adams, C.1
  • 8
    • 0037126526 scopus 로고    scopus 로고
    • Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). Circulation. 2002;106:3143-421. NIH publication no. 02-5215, September 2002. Available at: http://www.nhlbi.nih.gov/ guidelines/cholesterol/atp3full.pdf. Accessed July 2, 2006.
    • Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). Circulation. 2002;106:3143-421. NIH publication no. 02-5215, September 2002. Available at: http://www.nhlbi.nih.gov/ guidelines/cholesterol/atp3full.pdf. Accessed July 2, 2006.
  • 9
    • 4043103545 scopus 로고    scopus 로고
    • Quantifying the effect of applying the NCEP ATP III criteria in a managed care population treated with statin therapy
    • Quilliam BJ, Perez E, Andros V, Jones P. Quantifying the effect of applying the NCEP ATP III criteria in a managed care population treated with statin therapy. J Manag Care Pharm. 2004;10(3):244-50.
    • (2004) J Manag Care Pharm , vol.10 , Issue.3 , pp. 244-250
    • Quilliam, B.J.1    Perez, E.2    Andros, V.3    Jones, P.4
  • 10
    • 0242285687 scopus 로고    scopus 로고
    • The statin wars: why AstraZeneca must retreat [editorial]. Lancet. 2003;362(9393):1341.
    • The statin wars: why AstraZeneca must retreat [editorial]. Lancet. 2003;362(9393):1341.
  • 11
    • 34548619393 scopus 로고    scopus 로고
    • PFE: Net Lipitor US pricing, and how it compares to Crestor
    • February 2
    • Evans RT, Gandhi D, Kranson DB. PFE: Net Lipitor US pricing, and how it compares to Crestor. Bernstein Res Call. February 2, 2004.
    • (2004) Bernstein Res Call
    • Evans, R.T.1    Gandhi, D.2    Kranson, D.B.3
  • 12
    • 85039230127 scopus 로고    scopus 로고
    • Data search performed April 5, 2004, of the data warehouse of a national pharmacy benefits manager representing approximately 500,000 beneficiaries of small employer drug benefit plans for pharmacy claims with dates of service from January 1, 2004, through March 31, 2004.
    • Data search performed April 5, 2004, of the data warehouse of a national pharmacy benefits manager representing approximately 500,000 beneficiaries of small employer drug benefit plans for pharmacy claims with dates of service from January 1, 2004, through March 31, 2004.
  • 13
    • 1842427412 scopus 로고    scopus 로고
    • Evaluating the cost-effectiveness of statins
    • Hay JW. Evaluating the cost-effectiveness of statins. J Manag Care Pharm. 2004;10(1):79-81.
    • (2004) J Manag Care Pharm , vol.10 , Issue.1 , pp. 79-81
    • Hay, J.W.1
  • 14
    • 33645524176 scopus 로고    scopus 로고
    • writing for the ASTEROID investigators. Effect of very high-intensity statin therapy on regression of coronary atherosclerosis: The ASTEROID trial
    • Nissen SE, Nicholls SJ, Sipahi I., writing for the ASTEROID investigators. Effect of very high-intensity statin therapy on regression of coronary atherosclerosis: the ASTEROID trial. JAMA. 2006;295:1556-65.
    • (2006) JAMA , vol.295 , pp. 1556-1565
    • Nissen, S.E.1    Nicholls, S.J.2    Sipahi, I.3
  • 15
    • 1842584458 scopus 로고    scopus 로고
    • Challenges in evaluating the cost-effectiveness of statins
    • Ohsfeldt RL. Challenges in evaluating the cost-effectiveness of statins. J Manag Care Pharm. 2004;10(1):81-82.
    • (2004) J Manag Care Pharm , vol.10 , Issue.1 , pp. 81-82
    • Ohsfeldt, R.L.1
  • 16
    • 85039205889 scopus 로고    scopus 로고
    • Bristol-Myers, challenging Pfizer was a big mistake. In rare head-to-head study, Lipitor beats Pravachol at reducing heart risk
    • March 9
    • Winslow R. For Bristol-Myers, challenging Pfizer was a big mistake. In rare head-to-head study, Lipitor beats Pravachol at reducing heart risk. Wall Street Journal. March 9, 2004::A1, A8.
    • (2004) Wall Street Journal , vol.A1
    • For, W.R.1
  • 17
    • 11144355354 scopus 로고    scopus 로고
    • Intensive versus moderate lipid-lowering with statins after acute coronary syndromes
    • Cannon CP, Braunwald E, McCabe CH, et al. Intensive versus moderate lipid-lowering with statins after acute coronary syndromes. N Engl J Med. 2004;350:1495-1504.
    • (2004) N Engl J Med , vol.350 , pp. 1495-1504
    • Cannon, C.P.1    Braunwald, E.2    McCabe, C.H.3
  • 18
    • 3943059569 scopus 로고    scopus 로고
    • Intensive versus moderate lipid lowering with statins after acute coronary syndrome [letter]
    • Paradis JM, LeLorier J. Intensive versus moderate lipid lowering with statins after acute coronary syndrome [letter]. N Engl J Med. 2004;351:715.
    • (2004) N Engl J Med , vol.351 , pp. 715
    • Paradis, J.M.1    LeLorier, J.2
  • 19
    • 1942526703 scopus 로고    scopus 로고
    • Intensive versus moderate lipid lowering with statins after acute coronary syndrome [letter]
    • Cannon CP, Braunwald E. Intensive versus moderate lipid lowering with statins after acute coronary syndrome [letter]. N Engl J Med. 2004;351:716-17.
    • (2004) N Engl J Med , vol.351 , pp. 716-717
    • Cannon, C.P.1    Braunwald, E.2
  • 20
    • 85039209812 scopus 로고    scopus 로고
    • Lipitor prescriptions surge in wake of big study
    • March 18
    • Winslow R. Lipitor prescriptions surge in wake of big study. Wall Street Journal. March 18, 2004:D4.
    • (2004) Wall Street Journal
    • Winslow, R.1
  • 21
    • 15944410609 scopus 로고    scopus 로고
    • Intensive lipid lowering with atorvastatin in patients with stable coronary disease
    • LaRosa JC, Grundy SM, Waters DD, et al. Intensive lipid lowering with atorvastatin in patients with stable coronary disease. N Engl J Med. 2005;352: 1425-35.
    • (2005) N Engl J Med , vol.352 , pp. 1425-1435
    • LaRosa, J.C.1    Grundy, S.M.2    Waters, D.D.3
  • 22
    • 15944394012 scopus 로고    scopus 로고
    • Low-density lipoprotein cholesterol in patients with stable coronary heart disease - is it time to shift our goals?
    • Pitt B. Low-density lipoprotein cholesterol in patients with stable coronary heart disease - is it time to shift our goals? N Engl J Med. 2005;352:1483-84.
    • (2005) N Engl J Med , vol.352 , pp. 1483-1484
    • Pitt, B.1
  • 23
    • 21444455072 scopus 로고    scopus 로고
    • Intensive lipid lowering with atrovastatin in coronary disease [letter]
    • Auer J, Lamm G, Eber B. Intensive lipid lowering with atrovastatin in coronary disease [letter]. N Engl J Med. 2005;353:93.
    • (2005) N Engl J Med , vol.353 , pp. 93
    • Auer, J.1    Lamm, G.2    Eber, B.3
  • 24
    • 21444455072 scopus 로고    scopus 로고
    • Intensive lipid lowering with atrovastatin in coronary disease [letter]
    • Cannon CP, Murphy SA, Braunwald E. Intensive lipid lowering with atrovastatin in coronary disease [letter]. N Engl J Med. 2005;353:93-94.
    • (2005) N Engl J Med , vol.353 , pp. 93-94
    • Cannon, C.P.1    Murphy, S.A.2    Braunwald, E.3
  • 25
    • 85073894000 scopus 로고    scopus 로고
    • Intensive lipid lowering with atrovastatin in coronary disease [letter]
    • Southern W. Intensive lipid lowering with atrovastatin in coronary disease [letter]. N Engl J Med. 2005;353:95.
    • (2005) N Engl J Med , vol.353 , pp. 95
    • Southern, W.1
  • 26
    • 10744225301 scopus 로고    scopus 로고
    • Effect of intensive compared with moderate lipid-lowering therapy on progression of coronary atherosclerosis: A randomized controlled trial
    • for the REVERSAL investigators
    • Nissen SE, Tuzcu EM, Schoenhagen P, et al., for the REVERSAL investigators. Effect of intensive compared with moderate lipid-lowering therapy on progression of coronary atherosclerosis: a randomized controlled trial. JAMA. 2004;291(9):1071-80.
    • (2004) JAMA , vol.291 , Issue.9 , pp. 1071-1080
    • Nissen, S.E.1    Tuzcu, E.M.2    Schoenhagen, P.3
  • 28
    • 34548637068 scopus 로고    scopus 로고
    • New prescription for Zocor users
    • June 17-18
    • Winslow R. New prescription for Zocor users. Wall Street Journal. June 17-18, 2006:A2.
    • (2006) Wall Street Journal
    • Winslow, R.1
  • 29
    • 34548636766 scopus 로고    scopus 로고
    • US drugs: Crestor likely to outgrow its dangerous image, pressuring prices - an update on adverse event rates
    • June 6
    • Evans RT, Amusa G, Kranson DB, Parsons A. US drugs: Crestor likely to outgrow its dangerous image, pressuring prices - an update on adverse event rates. BernsteinResearch. June 6, 2006.
    • (2006) BernsteinResearch
    • Evans, R.T.1    Amusa, G.2    Kranson, D.B.3    Parsons, A.4
  • 30
    • 1542345696 scopus 로고    scopus 로고
    • Effects of cholesterol-lowering with simvastatin on stroke and other major vascular events in 20,536 people with cerebrovascular disease or other high-risk conditions
    • Heart Protection Study Collaborative Group
    • Heart Protection Study Collaborative Group. Effects of cholesterol-lowering with simvastatin on stroke and other major vascular events in 20,536 people with cerebrovascular disease or other high-risk conditions. Lancet. 2004;363: 757-67.
    • (2004) Lancet , vol.363 , pp. 757-767
  • 31
    • 4043113633 scopus 로고    scopus 로고
    • Methods to attain optimal outcomes with lipid-lowering drug therapy
    • Curtiss FR. Methods to attain optimal outcomes with lipid-lowering drug therapy. J Manag Care Pharm. 2004;10(3):267-70.
    • (2004) J Manag Care Pharm , vol.10 , Issue.3 , pp. 267-270
    • Curtiss, F.R.1
  • 34
    • 85039195098 scopus 로고    scopus 로고
    • Extended-release niacin (Niaspan) [prescribing information from the product label]. Drug Facts and Comparisons (Clinisphere version, ISBN 1-57439-036-8). St. Louis, MO: Wolters, Kluwer Health, Inc.; May 2006. Accessed June 25, 2006.
    • Extended-release niacin (Niaspan) [prescribing information from the product label]. Drug Facts and Comparisons (Clinisphere version, ISBN 1-57439-036-8). St. Louis, MO: Wolters, Kluwer Health, Inc.; May 2006. Accessed June 25, 2006.
  • 35
    • 33645566760 scopus 로고    scopus 로고
    • Risks and benefits of omega 3 fats for mortality, cardiovascular disease, and cancer: Systematic review
    • Hooper L, Thompson RL, Harrison RA, et al. Risks and benefits of omega 3 fats for mortality, cardiovascular disease, and cancer: systematic review. BMJ. 2006;332:752-760.
    • (2006) BMJ , vol.332 , pp. 752-760
    • Hooper, L.1    Thompson, R.L.2    Harrison, R.A.3
  • 36
    • 0037469232 scopus 로고    scopus 로고
    • Markers of inflammation and cardiovascular disease: Application to clinical and public health practice: a statement for healthcare professionals from the Centers for Disease Control and prevention and the American Health Association
    • Pearson TA, Mensah GA, Alexander RW, et al. Markers of inflammation and cardiovascular disease: application to clinical and public health practice: a statement for healthcare professionals from the Centers for Disease Control and prevention and the American Health Association. Circulation. 2003;107:499-511.
    • (2003) Circulation , vol.107 , pp. 499-511
    • Pearson, T.A.1    Mensah, G.A.2    Alexander, R.W.3
  • 37
    • 3142688449 scopus 로고    scopus 로고
    • C-reactive protein and coronary heart disease
    • Ridker PM, Koenig W, Fuster V, et al. C-reactive protein and coronary heart disease. N Engl J Med. 2004;351:295-97.
    • (2004) N Engl J Med , vol.351 , pp. 295-297
    • Ridker, P.M.1    Koenig, W.2    Fuster, V.3
  • 38
    • 34548611339 scopus 로고    scopus 로고
    • US drugs: How secure is torcetrapib's lead? A high level overview of the HDL pipeline
    • June 7
    • Evans RT, Kranson DB. US drugs: how secure is torcetrapib's lead? A high level overview of the HDL pipeline. BernsteinResearch. June 7, 2006.
    • (2006) BernsteinResearch
    • Evans, R.T.1    Kranson, D.B.2
  • 41
    • 85039204823 scopus 로고    scopus 로고
    • ClinicalTrials.gov identifier: NCT00134173 - A coronary IV US study to compare torcetrapib/atorvastatin to atorvastatin alone in subjects with coronary heart disease. Available at: http://www.clinicaltrials.gov/ct/show/NCT00134173. Accessed June 26, 2006.
    • ClinicalTrials.gov identifier: NCT00134173 - A coronary IV US study to compare torcetrapib/atorvastatin to atorvastatin alone in subjects with coronary heart disease. Available at: http://www.clinicaltrials.gov/ct/show/NCT00134173. Accessed June 26, 2006.
  • 42
    • 85039212702 scopus 로고    scopus 로고
    • Medscape coverage of the American Heart Association Scientific Sessions, November 13-16, Dallas, Texas. Available at:, Accessed July 17
    • Brookes L. Phase 2 studies with torcetrapib/atorvastatin combination. Medscape coverage of the American Heart Association Scientific Sessions, November 13-16, 2005, Dallas, Texas. Available at: http://www.medscape.com/ viewarticle/518571. Accessed July 17, 2006.
    • (2005) Phase 2 studies with torcetrapib/atorvastatin combination
    • Brookes, L.1
  • 43
    • 84856056070 scopus 로고    scopus 로고
    • Available at:, Accessed June 26, 2006
    • NHANES III data files. Available at: http://www.cdc.gov/nchs/about/major/ nhanes/nh3data.htm. Accessed June 26, 2006.
    • NHANES III data files
  • 44
    • 33646258753 scopus 로고    scopus 로고
    • Antagonism of the prostaglandin D2 receptor 1 suppresses nicotinic acid-induced vasodilatation in mice and humans
    • Cheng K, Wu TJ, Wu KK, et al. Antagonism of the prostaglandin D2 receptor 1 suppresses nicotinic acid-induced vasodilatation in mice and humans. Proc Natl Acad Sci. 2006;103(17):6682-87.
    • (2006) Proc Natl Acad Sci , vol.103 , Issue.17 , pp. 6682-6687
    • Cheng, K.1    Wu, T.J.2    Wu, K.K.3
  • 45
    • 85039190935 scopus 로고    scopus 로고
    • Available at:, Accessed July 2, 2006
    • Merck's report to shareholders 2005. Available at: http://www.merck.com/ finance/annualreport/ar2005/pdf/Merck_2005_Editorial_Section.pdf. Accessed July 2, 2006.
    • Merck's report to shareholders 2005
  • 46
    • 85039182693 scopus 로고    scopus 로고
    • ClinicalTrials.gov identifier: NCT00289900 - Lipid efficacy and safety in patients with mixed hyperlipidemia. Available at: http://www.clinicaltrials. gov/ct/show/NCT00289900;jsessionid=A3B351FC8F6B92AD2FAC5E585AFEDC3A?order=9. Accessed June 26, 2006.
    • ClinicalTrials.gov identifier: NCT00289900 - Lipid efficacy and safety in patients with mixed hyperlipidemia. Available at: http://www.clinicaltrials. gov/ct/show/NCT00289900;jsessionid=A3B351FC8F6B92AD2FAC5E585AFEDC3A?order=9. Accessed June 26, 2006.
  • 47
    • 85039222076 scopus 로고    scopus 로고
    • ClinicalTrials.gov identifier: NCT00269217 - A multicenter, randomized. double-blind, factorial design study to evaluate the lipid-altering efficacy and safety of coadministered MK0524A + simvastatin tablets in patients with primary hypercholesterolemia or mixed hyperlipidemia. Available at: http://www.clinicaltrials.gov/ct/show/NCT00269217. Accessed July 2, 2006.
    • ClinicalTrials.gov identifier: NCT00269217 - A multicenter, randomized. double-blind, "factorial" design study to evaluate the lipid-altering efficacy and safety of coadministered MK0524A + simvastatin tablets in patients with primary hypercholesterolemia or mixed hyperlipidemia. Available at: http://www.clinicaltrials.gov/ct/show/NCT00269217. Accessed July 2, 2006.
  • 48
    • 19944426989 scopus 로고    scopus 로고
    • A randomized trial of a strategy for increasing high-density lipoprotein cholesterol levels: Effects on progression of coronary heart disease and clinical events
    • Whitney EJ, Krasuski RA, Personius BE, et al. A randomized trial of a strategy for increasing high-density lipoprotein cholesterol levels: effects on progression of coronary heart disease and clinical events. Ann Intern Med. 2005;142:95-104.
    • (2005) Ann Intern Med , vol.142 , pp. 95-104
    • Whitney, E.J.1    Krasuski, R.A.2    Personius, B.E.3
  • 49
    • 20544454535 scopus 로고    scopus 로고
    • Torcetrapid and atorvastatin - should marketing drive the research agenda?
    • Avorn J. Torcetrapid and atorvastatin - should marketing drive the research agenda? N Engl J Med. 2005;325:2573-76.
    • (2005) N Engl J Med , vol.325 , pp. 2573-2576
    • Avorn, J.1
  • 50
    • 25844475356 scopus 로고    scopus 로고
    • Torcetapib and atorvastatin [letter]
    • Shear CL, Hirsch RL, Avorn J. Torcetapib and atorvastatin [letter]. N Engl J Med. 2006;353:1527-29.
    • (2006) N Engl J Med , vol.353 , pp. 1527-1529
    • Shear, C.L.1    Hirsch, R.L.2    Avorn, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.