ACE I/D gene polymorphism and aerobic endurance development in response to training in a non-elite female cohort

Journal of Sports Medicine and Physical Fitness

Volumn 47, Issue 2, 2007, Pages 234-238

  Cam, S ^a   Colakoglu, M ^b   Colakoglu, S ^a   Sekuri, C ^a   Berdeli, A ^b  

^a CELAL BAYAR UNIVERSITY   (Turkey)

^b EGE UNIVERSITY   (Turkey)

Author keywords

Deletion; Genetics; Insertion; Performance; Physical endurance

Indexed keywords

ACE PROTEIN, HUMAN; DIPEPTIDYL CARBOXYPEPTIDASE; UNCLASSIFIED DRUG;

ADULT; ANALYSIS OF VARIANCE; ARTICLE; CHI SQUARE DISTRIBUTION; ENDURANCE; EXERCISE TEST; FEMALE; GENE DELETION; GENETIC POLYMORPHISM; GENETICS; GENOTYPE; HUMAN; NONPARAMETRIC TEST; PHYSICAL EDUCATION; PHYSIOLOGY; POLYMERASE CHAIN REACTION; RUNNING;

ADULT; ANALYSIS OF VARIANCE; CHI-SQUARE DISTRIBUTION; EXERCISE TEST; FEMALE; GENE DELETION; GENOTYPE; HUMANS; PEPTIDYL-DIPEPTIDASE A; PHYSICAL EDUCATION AND TRAINING; PHYSICAL ENDURANCE; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; RUNNING; STATISTICS, NONPARAMETRIC;

EID: 34547257068     PISSN: 00224707     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Dragovic T, Minshall R, Jackman HL, Wang LX, Erdos EG. Kininase II-type enzymes: their putative role in muscle energy metabolism. Diabetes 1996;45 Suppl 1:S34-S37.
2. Rigat B, Hubert C, Corvol P, Soubrier F. PCR detection of the insertion/deletion polymorphism of the human angiotensin converting enzyme gene (DCP1) (dipeptidyl carboxypeptidase 1). Nucleic Acids Res 1992;20:1433.
3. Rigat B, Hubert C, Alhenc-Gelas F, Cambien F, Corvol P, Soubrier F. An insertion/deletion polymorphism in the angiotensin-1-converting enzyme gene accounting for half the variance of serum enzyme levels. J Clin Invest 1990;86:1343-6.
4. Alvarez R, Terrados N, Ortalano R, Iglesias-Cubero G, Requero JR, Batalla A et al. Genetic variation in the renin-angiotensin system and athletic performance. Eur J Appl Physiol 2000;82:117-20.
5. Gayagay G, Yu B, Hambly B, Boston T, Hahn A, Celermajer DS et al. Elite endurance athletes and the ACE I allele-the role of genes in athletic performance. Hum Genet 1998;103:48-50.
6. Montgomery HE, Marshall R, Hemingway H, Myerson S, Clarkson P, Dollery C et al. Human gene for physical performance. Nature 1998;393:221-2.
7. Myerson S, Hemingway H, Budget R, Martin J, Humphries S, Montgomery H. Human angiotensin I-converting enzyme gene and endurance performance. J Appl Physiol 1999;87:1313-6.
8. Nazarov IB, Woods DR, Montgomery H.E, Shneirder OV, Kazakov VI, Tomilin NV et al. The angiotensin converting enzyme I/D polymorphism in Russian athletes. Eur J Hum Genet 2001;9:797-801.
9. Rankinen T, Perusse L, Gagnon J, Chagnon YC, Leon AS, Skinner JS et al. Angiotensin-converting enzyme ID polymorphism and fitness phenotype in the HERITAGE Family Study. J Appl Physiol 2000;88:1029-35.
10. Woods D, Hickman M, Jamshidi Y, Brull D, Vassiliou V, Jones A et al. Elite swimmers and the D allele of the ACE I/D polymorphism. Hum Genet 2001;108:230-2.
11. Rankinen T, Wolfarth B, Simoneau JA, Maier-Lenz D, Rauramaa R, Rivera MA et al. No association between the angiotensin-converting enzyme ID polymorphism and elite endurance athlete status. J Appl Physiol 2000;88:1571-5.
12. Taylor RR, Mamotte CD, Fallon K, van Bockxmeer FM. Elite athletes and gene for angiotensin-converting enzyme. J Appl Physiol 1999;87:1035-7.
13. Jones A, Montgomery HE, Woods DR. Human performance: a role for the ACE genotype. Exerc Sport Sci Rev 2002;30:184-90.
14. 2max of Chinese males. Life Sci 2003;73:2625-30.
15. Cam S, Colakogfu M, Sekuri C. Colakoglu S, Sahan C, Berdeli A. Association between the ACE I/D polymorphism and physical performance in a homogeneous non-elite cohort. Can J Appl Physiol 2005;30:74-86.
16. Karvonen MJ, Kentala E, Mustala O. The effects of training on heart rate; a longitudinal study. Ann Med Exp Biol Fenn 1957;35:307-15.
17. Shanmugam V, Sell KW, Saha BK. Mistyping ACE heterozygotes. PCR Methods Appl 1993;3:120-1.
18. Woods DR, World M, Tayson MP, Williams AC. Jubb M, Jamshidi Y et al. Endurance enhancement related to the human angiotensin I-converting enzyme I-D polymorphism is not due to differences in the cardiorespiratory response to training. Eur J Appl Physiol 2002;86:240-4.
19. Zhang B, Tanaka H. Shono N, Miura S, Kiyonaga A, Shindo M et al The 1 allele of the angiotensin-converting enzyme gene is associated with an increased percentage of slow-twitch type I fibers in human skeletal muscle. Clin Genet 2003;63:139-44.
20. Montgomery HE, Clarkson P, Dollery CM, Prasad K, Lost MA, Hemingvay H et al. Association of angiotensin-converting enzyme gene I/D polymorphism with change in left ventricular mass in response to physical training. Circulation 1997;96:741-7.
21. Montgomery H, Brull D, Humphries SE. Analysis of gene-environment interactions by "stressing-the-genotype" studies: the angiotensin converting enzyme and exercise-induced left ventricular hypertrophy as an example. Ital Heart J 2002;3:10-4.
22. Myerson SG, Montgomery HE, Whittingham M, World MJ, Humphries SE, Pennell DJ. Left ventricular hypertrophy with exercise and ACE gene insertion/deletion polymorphism: a randomized controlled trial with losartan. Circulation 2001;103:226-30.
23. Holland J, Leach B, Little T, Hawker K, Myerson S, Montgomery H et al. Angiotensin-converting enzyme genotype affects the response of human skeletal muscle to functional overload. Exp Physiol 2000;85:575-9
24. Hopkinson NS, Nickol AH, Payne J, Hawe E. Man WDC, Moxham J et al. Angiotensin converting enzyme genotype and strength in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2004;170:395-9.
25. Thomis MA, Huygens W, Heuninckx S, Chagnon M, Maes HH, Claessens AL et al. Exploration of myostatin polymorphisms and the angiotensin-converting enzyme insertion/deletion genotype in responses of human muscle to strength training. Eur J Appl Physiol 2004;92:267-74.
26. 2max is associated with ACE genotype in post-menopausal women. J Appl Physiol 1998;85:1842-6.