Locally targeted drug delivery to magnetic stents for therapeutic applications

2004 2nd IEEE/EMBS International Summer School on Medical Devices and Biosensors, ISSS-MDBS 2004

Volumn , Issue , 2004, Pages 1-6

  Forbes, Z G ^a   Halverson, D S ^b   Fridman, G ^a   Yellen, B B ^b   Chorny, M ^c   Friedman, G ^b   Barbee, K A ^a  

^a DREXEL UNIVERSITY   (United States)

^b Drexel University   (United States)

^c CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

Author keywords

Drug delivery; Magnetic targeting; Stent

Indexed keywords

BODY FLUIDS; DRUG DOSAGE; MAGNETIC FIELDS; SUPERPARAMAGNETISM; TOXICITY;

COLLOIDAL FLUID; HUMAN BODY; MAGNETIC COILS; MAGNETIC STENTS; THERAPEUTIC APPLICATIONS;

DRUG DELIVERY;

EID: 34547244663     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: None     Document Type: Conference Paper

References (22)

1. S.M. Garas, P. Huber, N.A. Scott, "Overview of therapies for prevention of restenosis after coronary interventions," Pharmacology and Therapeutics, vol. 92, pp. 165-78, 2001.
2. Hehrlein, C. et al. "Drug-eluting stent: the 'magic bullet' for prevention of restenosis?" Basic Res. Cardiol., vol. 97, pp. 417-23, 2002.
3. Gershlick, A.H. et al. "Treating atherosclerosis: local drug delivery from laboratory studies to clinical trials," Atherosclerosis, vol. 160: 259-71, 2002.
4. K. Mossbach, U. Schroder, "Preparation and characterization of magnetic polymers for targeting of drugs," FEBS Letters, vol, 102, pp. 112-116, 1979.
5. J.M, Gallo, U. Häfeli, Correspondence re: A.S. Lübbe et al., "Preclinical and clinical experiences with magnetic drug targeting," Cancer Res., vol. 57, pp. 3063-3064, 1997.
6. A. S. Lübbe, C, Alexiou, C. Bergemann, "Clinical applications of magnetic drug targeting," J Surg Res, vol. 95, pp. 200-206, 2001.
7. S. Rudge, C. Peterson, C. Vessely, J. Koda, S. Stevens, L. Catterall, "Adsorption and desorption of chemotherapeutic drugs from a magnetically targeted carrier (MTC)," J Controlled Release, vol. 74, pp. 335-340, 2001.
8. G. A. Flores, "In-vitro blockage of a simulated vascular system using magnetorheological fluids as a cancer therapy," Eur. Cells and Mater., vol. 3, pp. 9-11, 2002.
9. S. P. Vyas, A. Singh, V. Sihorkar, "Ligand-receptor-mediated drug delivery: an emerging paradigm in cellular drug targeting," Crit. Rev. Ther. Drug Carrier Syst., vol. 18(1), pp. 1-76, 2001.
10. Y. Xia, G.M. Whitesides, "Soft Lithography," Annu. Rev. Mater. Sci., vol. 28, pp. 153-184, 1998.
11. H. Schewe, M. Takayasu, F.J. Friendlaender, "Observation of Particle Trajectories in an HGMS Single-Wire System," IEEE Trans. Magn., vol .Mag-16, no.1, pp. 149-154, 1980.
12. F.J. Friedlaender, R. Gerber, W. Kurzl, R.R. Birss, "Particle Motion Near and Capture on Single Spheres in HGMS," IEEE Trans. Magn., vol. Mag-17, no, 6, pp..2801-2803
13. F.J. Friedlaender, R. Gerber, H.P. Henkel, R.R. Birss, "Particle Buildup on Single Spheres in HGMS," IEEE Trans. Magn., vol. Mag-17, no. 6, pp..2804-2806.
14. P. A. Volteiras, D. I. Fotiadis, L. K. Michalis, "Hydrodynamics of magnetic drug targeting," vol. 35(6), pp. 813-821, June 2002.
15. G. Segre and A. Silberberg, "Behaviour of macroscopic rigid spheres in Poiseuille flow Part 1 & 2," J. Fluid Mech., vol. 14, pp 115-157, 1962.
16. F.A. Loweinheim. Electroplating. New York: McGraw-Hill.
17. Z.G. Forbes, B.B. Yellen, K.A. Barbee, G. Friedman,. "An Approach to Targeted Drug Delivery Based on Uniform Magnetic Fields." IEEE Transactions on Magnetics, vol. 39, pp. 3372-3377, September 2003.
18. E, Regar, et al. "Stent development and local drug delivery," Br. Med. Bull.., vol. 59, pp. 227-248, 2001.
19. R.S. Schwartz, et al. "Drug-Eluting Stents in Preclinical Studies: Recommended Evaluation From a Consensus Group," Circulation., vol.. 106, pp. 1867-73, 2002.
20. M. Duch, "Electrodeposited Co-Ni alloys for MEMS," J. Micromech. Microeng., vol 12, pp. 400-405, 2002.
21. N. V, Myung et al. "Electrodeposited Hard Magnetic Thin Films for MEMS Applications," Proc. Electrochem. Soc. PV, pp. 2000-2029, 2000.
22. B.B. Yellen, Z.G. Forbes, K.A. Barbee, G. Friedman, "Model of an Approach to Targeted Drug Delivery Based on Uniform Magnetic Fields"presented at the 6th Annual New Jersey Symposium on Biomaterials, October 17-18, 2002, Somerset, NJ.