-
1
-
-
0036218976
-
Time course of platelet counts in critically ill patients
-
Akca S, Haji-Michael P, de Mendonca A, Suter P, Levi M, Vincent JL. Time course of platelet counts in critically ill patients. Crit Care Med 2002;4:753-756.
-
(2002)
Crit Care Med
, vol.4
, pp. 753-756
-
-
Akca, S.1
Haji-Michael, P.2
de Mendonca, A.3
Suter, P.4
Levi, M.5
Vincent, J.L.6
-
2
-
-
0032894825
-
Thrombocytopenia in a surgical ICU
-
Stephan F, Hollande J, Richard O, Cheffi A, Maier-Redelsperger M, Flahault A. Thrombocytopenia in a surgical ICU. Chest 1999;5:1363-1370.
-
(1999)
Chest
, vol.5
, pp. 1363-1370
-
-
Stephan, F.1
Hollande, J.2
Richard, O.3
Cheffi, A.4
Maier-Redelsperger, M.5
Flahault, A.6
-
4
-
-
0030910382
-
Platelet function in septic multiple organ dysfunction syndrome
-
Gawaz M, Dickfeld T, Bogner C, Fateh-Moghadam S, Neumann FJ. Platelet function in septic multiple organ dysfunction syndrome. Intensive Care Med 1997;4:379-385.
-
(1997)
Intensive Care Med
, vol.4
, pp. 379-385
-
-
Gawaz, M.1
Dickfeld, T.2
Bogner, C.3
Fateh-Moghadam, S.4
Neumann, F.J.5
-
5
-
-
0035826096
-
Efficacy and safety of recombinant human activated protein C for severe sepsis
-
Bernard GR, Vincent JL, Laterre PF, LaRosa SP, Dhainaut JF, Lopez-Rodriguez A, Steingrub JS, Garber GE, Helterbrand JD, Ely EW, Fisher CJ, Jr. Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med 2001;10:699-709.
-
(2001)
N Engl J Med
, vol.10
, pp. 699-709
-
-
Bernard, G.R.1
Vincent, J.L.2
Laterre, P.F.3
LaRosa, S.P.4
Dhainaut, J.F.5
Lopez-Rodriguez, A.6
Steingrub, J.S.7
Garber, G.E.8
Helterbrand, J.D.9
Ely, E.W.10
Fisher Jr., C.J.11
-
6
-
-
0034925134
-
Protein C anticoagulant pathway and its role in controlling microvascular thrombosis and inflammation
-
discussion 51-42
-
Esmon CT. Protein C anticoagulant pathway and its role in controlling microvascular thrombosis and inflammation. Crit Care Med 2001;7 Suppl:S48-S51. discussion 51-42.
-
(2001)
Crit Care Med
, vol.7
, Issue.SUPPL.
-
-
Esmon, C.T.1
-
7
-
-
0036917329
-
Relationship between the inflammation and coagulation pathways in patients with severe sepsis: Implications for therapy with activated protein C
-
Morris PE, Hite RD, Ohl C. Relationship between the inflammation and coagulation pathways in patients with severe sepsis: implications for therapy with activated protein C. Bio Drugs 2002;6:403-417.
-
(2002)
Bio Drugs
, vol.6
, pp. 403-417
-
-
Morris, P.E.1
Hite, R.D.2
Ohl, C.3
-
8
-
-
0035815747
-
Gene expression profile of antithrombotic protein C defines new mechanisms modulating inflammation and apoptosis
-
Joyce DE, Gelbert L, Ciaccia A, DeHoff B, Grinnell BW. Gene expression profile of antithrombotic protein C defines new mechanisms modulating inflammation and apoptosis. J Biol Chem 2001;14:11199-11203.
-
(2001)
J Biol Chem
, vol.14
, pp. 11199-11203
-
-
Joyce, D.E.1
Gelbert, L.2
Ciaccia, A.3
DeHoff, B.4
Grinnell, B.W.5
-
9
-
-
0036202034
-
Drotrecogin alfa (activated)
-
discussion 631-612
-
Lyseng-Williamson KA, Perry CM. Drotrecogin alfa (activated). Drugs 2002;4:617-630; discussion 631-612.
-
(2002)
Drugs
, vol.4
, pp. 617-630
-
-
Lyseng-Williamson, K.A.1
Perry, C.M.2
-
10
-
-
0030740475
-
In vitro studies on the effect of activated protein C on platelet activation and thrombin generation
-
Kaiser B, Jeske W, Hoppensteadt DH, Walenga JM, Drohan W, Fareed J. In vitro studies on the effect of activated protein C on platelet activation and thrombin generation. Thromb Res 1997;2:197-204.
-
(1997)
Thromb Res
, vol.2
, pp. 197-204
-
-
Kaiser, B.1
Jeske, W.2
Hoppensteadt, D.H.3
Walenga, J.M.4
Drohan, W.5
Fareed, J.6
-
11
-
-
1242337462
-
New treatment strategies for disseminated intravascular coagulation based on current understanding of the pathophysiology
-
Levi M, de Jonge E, van der Poll T. New treatment strategies for disseminated intravascular coagulation based on current understanding of the pathophysiology. Ann Med 2004;1:41-49.
-
(2004)
Ann Med
, vol.1
, pp. 41-49
-
-
Levi, M.1
de Jonge, E.2
van der Poll, T.3
-
12
-
-
0037389471
-
Safety assessment of drotrecogin alfa (activated) in the treatment of adult patients with severe sepsis
-
Bernard GR, Macias WL, Joyce DE, Williams MD, Bailey J, Vincent JL. Safety assessment of drotrecogin alfa (activated) in the treatment of adult patients with severe sepsis. Crit Care 2003;2:155-163.
-
(2003)
Crit Care
, vol.2
, pp. 155-163
-
-
Bernard, G.R.1
Macias, W.L.2
Joyce, D.E.3
Williams, M.D.4
Bailey, J.5
Vincent, J.L.6
-
13
-
-
0026710191
-
Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis
-
American College of Chest Physicians/Society of Critical Care Medicine. Chest
-
Bone RC, Balk RA, Cerra FB, Dellinger RP, Fein AM, Knaus WA, Schein RM, Sibbald WJ. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine. Chest 1992;6:1644-1655.
-
(1992)
The ACCP/SCCM Consensus Conference Committee
, vol.6
, pp. 1644-1655
-
-
Bone, R.C.1
Balk, R.A.2
Cerra, F.B.3
Dellinger, R.P.4
Fein, A.M.5
Knaus, W.A.6
Schein, R.M.7
Sibbald, W.J.8
-
14
-
-
0016772924
-
Relation between the shape of population distribution and the robustness of four simple test statistics
-
Pearson ES, Please NW. Relation between the shape of population distribution and the robustness of four simple test statistics. Biometrika 1975;62:223-241.
-
(1975)
Biometrika
, vol.62
, pp. 223-241
-
-
Pearson, E.S.1
Please, N.W.2
-
15
-
-
0037248228
-
Drotrecogin alfa (activated) (recombinant human activated protein C) for the treatment of severe sepsis
-
Bernard GR. Drotrecogin alfa (activated) (recombinant human activated protein C) for the treatment of severe sepsis. Crit Care Med 2003;1 Suppl:S85-S93.
-
(2003)
Crit Care Med
, vol.1
, Issue.SUPPL.
-
-
Bernard, G.R.1
-
16
-
-
26444604781
-
Drotrecogin alfa (activated) treatment in severe sepsis from the global open-label trial ENHANCE: Further evidence for survival and safety and implications for early treatment
-
Vincent JL, Bernard GR, Beale R, Doig C, Putensen C, Dhainaut JF, Artigas A, Fumagalli R, Macias W, Wright T et al. Drotrecogin alfa (activated) treatment in severe sepsis from the global open-label trial ENHANCE: further evidence for survival and safety and implications for early treatment. Crit Care Med 2005;10:2266-2277.
-
(2005)
Crit Care Med
, vol.10
, pp. 2266-2277
-
-
Vincent, J.L.1
Bernard, G.R.2
Beale, R.3
Doig, C.4
Putensen, C.5
Dhainaut, J.F.6
Artigas, A.7
Fumagalli, R.8
Macias, W.9
Wright, T.10
-
17
-
-
25444492831
-
Drotrecogin alfa (activated) for adults with severe sepsis and a low risk of death
-
Abraham E, Laterre PF, Garg R, Levy H, Talwar D, Trzaskoma BL, Francois B, Guy JS, Bruckmann M, Rea-Neto A et al. Drotrecogin alfa (activated) for adults with severe sepsis and a low risk of death. N Engl J Med 2005;13:1332-1341.
-
(2005)
N Engl J Med
, vol.13
, pp. 1332-1341
-
-
Abraham, E.1
Laterre, P.F.2
Garg, R.3
Levy, H.4
Talwar, D.5
Trzaskoma, B.L.6
Francois, B.7
Guy, J.S.8
Bruckmann, M.9
Rea-Neto, A.10
-
18
-
-
0026448226
-
Inhibitory effect of activated protein C on platelet aggregation induced by the prothrombin- converting reaction
-
Komoriya K, Inoue K, Takahashi K, Suzuki K. Inhibitory effect of activated protein C on platelet aggregation induced by the prothrombin- converting reaction. Thromb Res 1992;6:705-710.
-
(1992)
Thromb Res
, vol.6
, pp. 705-710
-
-
Komoriya, K.1
Inoue, K.2
Takahashi, K.3
Suzuki, K.4
-
19
-
-
0141567620
-
Recombinant human activated protein C (rhAPC, drotrecogin alfa activated) has minimal effect on markers of coagulation, fibrinolysis and inflammation in acute human endotoxemia
-
Derhaschnig U, Reiter R, Knobl P, Baumgartner M, Keen P, Jilma B. Recombinant human activated protein C (rhAPC, drotrecogin alfa activated) has minimal effect on markers of coagulation, fibrinolysis and inflammation in acute human endotoxemia. Blood 2003;102:2093-2098.
-
(2003)
Blood
, vol.102
, pp. 2093-2098
-
-
Derhaschnig, U.1
Reiter, R.2
Knobl, P.3
Baumgartner, M.4
Keen, P.5
Jilma, B.6
-
20
-
-
0034307532
-
The GPIb thrombin-binding site is essential for thrombin-induced platelet procoagulant activity
-
Dormann D, Clemetson KJ, Kehrel BE. The GPIb thrombin-binding site is essential for thrombin-induced platelet procoagulant activity. Blood 2000;7:2469-2478.
-
(2000)
Blood
, vol.7
, pp. 2469-2478
-
-
Dormann, D.1
Clemetson, K.J.2
Kehrel, B.E.3
-
21
-
-
0034763808
-
Both the high affinity thrombin receptor (GPIb-IX-V) and GPIIb/IIIa are implicated in expression of thrombin-induced platelet procoagulant activity
-
Dicker IB, Pedicord DL, Seiffert DA, Jamieson GA, Greco NJ. Both the high affinity thrombin receptor (GPIb-IX-V) and GPIIb/IIIa are implicated in expression of thrombin-induced platelet procoagulant activity. Thromb Haemost 2001;4:1065-1069.
-
(2001)
Thromb Haemost
, vol.4
, pp. 1065-1069
-
-
Dicker, I.B.1
Pedicord, D.L.2
Seiffert, D.A.3
Jamieson, G.A.4
Greco, N.J.5
-
22
-
-
0023185062
-
Detection of activated platelets in whole blood using activation-dependent monoclonal antibodies and flow cytometry
-
Shattil SJ, Cunningham M, Hoxie JA. Detection of activated platelets in whole blood using activation-dependent monoclonal antibodies and flow cytometry. Blood 1987;1:307-315.
-
(1987)
Blood
, vol.1
, pp. 307-315
-
-
Shattil, S.J.1
Cunningham, M.2
Hoxie, J.A.3
-
23
-
-
0034831048
-
Platelets, leukocytes, and coagulation
-
Bouchard BA, Tracy PB. Platelets, leukocytes, and coagulation. Curr Opin Hematol 2001;5:263-269.
-
(2001)
Curr Opin Hematol
, vol.5
, pp. 263-269
-
-
Bouchard, B.A.1
Tracy, P.B.2
-
24
-
-
0028808810
-
Platelet activation and interaction with leucocytes in patients with sepsis or multiple organ failure
-
Gawaz M, Fateh-Moghadam S, Pilz G, Gurland HJ, Werdan K. Platelet activation and interaction with leucocytes in patients with sepsis or multiple organ failure. Eur J Clin Invest 1995;11:843-851.
-
(1995)
Eur J Clin Invest
, vol.11
, pp. 843-851
-
-
Gawaz, M.1
Fateh-Moghadam, S.2
Pilz, G.3
Gurland, H.J.4
Werdan, K.5
-
25
-
-
0036597565
-
Mechanisms of platelet-neutrophil interactions and effects on cell filtration in septic shock
-
Kirschenbaum LA, Adler D, Astiz ME, Barua RS, Saha D, Rackow EC. Mechanisms of platelet-neutrophil interactions and effects on cell filtration in septic shock. Shock 2002;6:508-512.
-
(2002)
Shock
, vol.6
, pp. 508-512
-
-
Kirschenbaum, L.A.1
Adler, D.2
Astiz, M.E.3
Barua, R.S.4
Saha, D.5
Rackow, E.C.6
-
26
-
-
3042571475
-
Effects of drotrecogin alfa (activated) in human endotoxemia
-
Kalil AC, Coyle SM, Um JY, LaRosa SP, Turlo MA, Calvano SE, Sundin DP, Nelson DR, Lowry SF. Effects of drotrecogin alfa (activated) in human endotoxemia. Shock 2004;3:222-229.
-
(2004)
Shock
, vol.3
, pp. 222-229
-
-
Kalil, A.C.1
Coyle, S.M.2
Um, J.Y.3
LaRosa, S.P.4
Turlo, M.A.5
Calvano, S.E.6
Sundin, D.P.7
Nelson, D.R.8
Lowry, S.F.9
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