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The IPI-O protein produced by Phytophthora infestans during plant infection contains the RGD tripeptide motif known to mediate extracellular and membrane adhesion in mammalian cells. There has been only scattered evidence of RGD effects in plant cells; however, the authors have shown that, through its RGD domain, IPI-O binds to an 80 kDa Arabidopsis plasma membrane protein and disrupts plant plasma membrane-cell wall connections. In this paper, the authors use phage display to identify a receptor kinase possessing a lectin-like extracellular domain that binds RGD-containing peptides and proteins.
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Gouget A., Senchou V., Govers F., Sanson A., Barre A., Rougé P., Pont-Lezica R., and Canut H. Lectin receptor kinases participate in protein-protein interactions to mediate plasma membrane-cell wall adhesions in Arabidopsis. Plant Physiol 140 (2006) 81-90. The IPI-O protein produced by Phytophthora infestans during plant infection contains the RGD tripeptide motif known to mediate extracellular and membrane adhesion in mammalian cells. There has been only scattered evidence of RGD effects in plant cells; however, the authors have shown that, through its RGD domain, IPI-O binds to an 80 kDa Arabidopsis plasma membrane protein and disrupts plant plasma membrane-cell wall connections. In this paper, the authors use phage display to identify a receptor kinase possessing a lectin-like extracellular domain that binds RGD-containing peptides and proteins.
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In earlier studies, the role of the AtSYP121/PEN1 syntaxin in mediating penetration resistance has been well documented. In this paper, the authors demonstrate that AtSYP121/PEN1 and a second syntaxin, AtSYP122, act as negative regulators of hypersensitive cell death and the salicylic acid, jasmonate and ethylene defence pathways. Enhanced necrosis in Atsyp121/Atsyp122 double mutants leads to increased resistance to the normally virulent Arabidopsis powdery mildew fungus.
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Zhang Z., Feechan A., Pedersen C., Newman M.-A., Qui J., Olesen K.L., and Thordal-Christensen H. A SNARE-protein has opposing functions in penetration resistance and defence signalling pathways. Plant J 49 (2007) 302-312. In earlier studies, the role of the AtSYP121/PEN1 syntaxin in mediating penetration resistance has been well documented. In this paper, the authors demonstrate that AtSYP121/PEN1 and a second syntaxin, AtSYP122, act as negative regulators of hypersensitive cell death and the salicylic acid, jasmonate and ethylene defence pathways. Enhanced necrosis in Atsyp121/Atsyp122 double mutants leads to increased resistance to the normally virulent Arabidopsis powdery mildew fungus.
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