The Female Athlete Triad and Cardiovascular Dysfunction

Physical Medicine and Rehabilitation Clinics of North America

Volumn 18, Issue 3, 2007, Pages 385-400

  Hoch, Anne Z ^a   Lal, Sophia ^a   Jurva, Jason W ^a   Gutterman, David D ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ETHINYLESTRADIOL PLUS LEVONORGESTREL; LIPID; LOW DENSITY LIPOPROTEIN CHOLESTEROL;

AMENORRHEA; ANOREXIA NERVOSA; ATHEROSCLEROSIS; BINGE EATING DISORDER; BONE DENSITOMETRY; BONE DENSITY; BULIMIA; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CELL PROLIFERATION; CORRELATION ANALYSIS; EATING DISORDER; FEMALE ATHLETE TRIAD; HIGH RISK POPULATION; HUMAN; LEUKOCYTE ADHERENCE; LOW DRUG DOSE; MENSTRUAL CYCLE; MENSTRUATION DISORDER; OSTEOPOROSIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; REVIEW; RISK ASSESSMENT; RISK FACTOR; SMOOTH MUSCLE FIBER; THROMBOCYTE AGGREGATION; VASODILATATION;

ADOLESCENT; ADULT; CARDIOVASCULAR DISEASES; CHILD; FEMALE; FEMALE ATHLETE TRIAD SYNDROME; HUMANS;

EID: 34547210707     PISSN: 10479651     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pmr.2007.05.001     Document Type: Review

References (62)

1. Thune I., Brenn T., Lund E., et al. Physical activity and the risk of breast cancer. N Engl J Med 336 18 (1997) 1269-1275
2. Lopiano D. Gender equity in sports. In: Agostini R. (Ed). Medical and orthopedic issues of active and athletic women (1994), Hanley & Belfus, Philadelphia 13-22
3. Prince R.L., Smith M., Dick I.M., et al. Prevention of postmenopausal osteoporosis. A comparative study of exercise, calcium supplementation, and hormone-replacement therapy. N Engl J Med 325 17 (1991) 1189-1195
4. Nichols D.L., Bonnick S.L., and Sanborn C.F. Bone health and osteoporosis. Clin Sports Med 19 2 (2000) 233-249
5. Teegarden D., Proulx W.R., Kern M., et al. Previous physical activity relates to bone mineral measures in young women. Med Sci Sports Exerc 28 (1996) 105-113
6. Lebrun C.M. Effects of the menstrual cycle and birth control pills on athletic performance. In: Agostini R. (Ed). Medical and orthopaedic issues of active and athletic women (1994), Hanely & Belfus, Philadelphia 78-91
7. Otis C.L., Drinkwater B., Johnson M., et al. American College of Sports Medicine position stand. The female athlete triad. Med Sci Sports Exerc 29 5 (1997) 1669-1671
8. Nichols J.F., Rauh M.J., Lawson M.J., et al. Prevalence of the female athlete triad syndrome among high school athletes. Arch Pediatr Adolesc Med 160 2 (2006) 137-142
9. Fairburn C.G., and Beglin S.J. Assessment of eating disorders: interview or self-report questionnaire?. Int J Eat Disord 16 4 (1994) 363-370
10. Hoch A.Z., Stavrakos J.E., Bobb V.L., et al. Prevalence of components of the Female Athlete Triad in high school athletes. Med Sci Sports Exerc 38 5 (2006) S345
11. Sundgot-Borgen J. Prevalence of eating disorders in elite female athletes. Int J Sport Nutr 3 1 (1993) 29-40
12. Rosen L.W., McKeag D.B., Hough D.O., et al. Pathogenic weight-control behavior in female athletes. The Physician and Sportsmedicine 14 1 (1986) 79-86
13. Nattiv A. The female athlete triad. In: Garrett W.E., Lester G.E., McGowan J., et al. (Eds). Women's health in sports and exercise (2001), American Academy of Orthopaedic Surgeons, Rosemont (IL) 451-465
14. In: Brownell K., and Foryet J. (Eds). Handbook of eating disorders: physiology, psychology and treatment of obesity, anorexia nervosa and bulimia nervosa (1986), Basic Books, New York
15. In: Fairburn C.G., and Brownell K. (Eds). Eating disorders and obesity: a comprehensive handbook. 2nd edition (2001), Gilford Press, New York
16. Sundgot-Borgen J., and Torstveit M.K. Prevalence of eating disorders in elite athletes is higher than in the general population. Clin J Sport Med 14 1 (2004) 25-32
17. Fogelholm M., and Hiilloskorpi H. Weight and diet concerns in Finnish female and male athletes. Med Sci Sports Exerc 31 2 (1999) 229-235
18. American Psychiatric Association. Eating Disorders. In: First M. (Ed). Diagnostic and statistical manual of mental disorders. 4th edition (1994), American Psychiatric Publishing, Inc., Washington, DC 539-550
19. Sanborn C.F., Horea M., Siemers B.J., et al. Disordered eating and the female athlete triad. Clin Sports Med 19 2 (2000) 199-213
20. Burckes-Miller M.E., and Black D.R. Male and female college athletes: prevalence of anorexia nervosa and bulimia nervosa. Athletic Training 23 (1988) 137-140
21. Brownell K., and Rodin J. Prevalence of eating disorders in athletes. In: Brownell K., Rodin J., and Wilmore J. (Eds). Eating, body weight and performance in athletes: disorders of modern society (1992), Lea & Febiger, Philadelphia 128-145
22. Byrne S., and McLean N. Eating disorders in athletes: a review of the literature. J Sci Med Sport 4 2 (2001) 145-159
23. Garner D.M., Olmstead M.P., and Polivy J. Development and validation of a multidimensional eating disorder inventory for anorexia nervosa and bulimia. International Journal of Eating Disorders 2 2 (1983) 15-34
24. Garner D.M., Olmsted M.P., Bohr Y., et al. The eating attitudes test: psychometric features and clinical correlates. Psychol Med 12 4 (1982) 871-878
25. Stunkard A.J., Sorensen T., and Schulsinger F. Use of the Danish Adoption Register for the study of obesity and thinness. Res Publ Assoc Res Nerv Ment Dis 60 (1983) 115-120
26. Lebrun C.M. Special issues of the female athlete. In: Johnson R. (Ed). Sports medicine in primary care (2000), W.B. Saunders, Philadelphia 243-255
27. Warren M.P., and Perlroth N.E. The effects of intense exercise on the female reproductive system. J Endocrinol 170 1 (2001) 3-11
28. Practice Committee of the American Society for Reproductive Medicine. Current evaluation of amenorrhea. Fertil Steril 82 1 (2004) 266-272
29. Drinkwater B.L., Nilson K., Chesnut C.H., et al. Bone mineral content of amenorrheic and eumenorrheic athletes. N Engl J Med 311 5 (1984) 277-281
30. Gibson J.H., Mitchell A., Reeve J., et al. Treatment of reduced bone mineral density in athletic amenorrhea: a pilot study. Osteoporos Int 10 4 (1999) 284-289
31. Hergenroeder A.C. Bone mineralization, hypothalamic amenorrhea, and sex steroid therapy in female adolescents and young adults. J Pediatr 126 5 Pt 1 (1995) 683-689
32. Nattiv A., and Armsey Jr. T.D. Stress injury to bone in the female athlete. Clin Sports Med 16 2 (1997) 197-224
33. De Souza M.J., Miller B.E., Loucks A.B., et al. High frequency of luteal phase deficiency and anovulation in recreational women runners: blunted elevation in follicle-stimulating hormone observed during luteal-follicular transition. J Clin Endocrinol Metab 83 12 (1998) 4220-4232
34. Shangold M., Freeman R., Thysen B., et al. The relationship between long-distance running, plasma progesterone, and luteal phase length. Fertil Steril 31 2 (1979) 130-133
35. Loucks A.B., Verdun M., and Heath E.M. Low energy availability, not stress of exercise, alters LH pulsatility in exercising women. J Appl Physiol 84 1 (1998) 37-46
36. NIH Consensus conference. Optimal calcium intake. NIH Consensus Development Panel on optimal calcium intake. JAMA 272 24 (1994) 1942-1948
37. Weaver C.M., Teegarden D., Lyle R.M., et al. Impact of exercise on bone health and contraindication of oral contraceptive use in young women. Med Sci Sports Exerc 33 6 (2001) 873-880
38. NIH News Release. "Calcium crisis" affects. American youth. expanded web site seeks to inform children of dangers of low calcium intake. 2001. Available at: http://www.nih.gov/news/pr/dec2001/nichd-10.htm. Accessed June 25, 2006.
39. IOC Medical Commission Working Group Women in Sport. Position stand on the female athlete triad. Available at: www.olympic.org/common/asp/download_report.asp?file=en_report_917.pdf&;id=917. Accessed December 2, 2006.
40. World Health Organization. Assessment of risk fracture and its application to screening for postmenopausal osteoporosis. World Health Organ Tech Rep Ser 843 (1994) 1-129
41. Leib E.S., Lewiecki E.M., Binkley N., et al. Official positions of the International Society for Clinical Densitometry. J Clin Densitom 7 1 (2004) 1-6
42. Torstveit M.K., and Sundgot-Borgen J. Low bone mineral density is two to three times more prevalent in non-athletic premenopausal women than in elite athletes: a comprehensive controlled study. Br J Sports Med 39 5 (2005) 282-287
43. Barrett-Connor E., and Bush T.L. Estrogen and coronary heart disease in women. JAMA 265 14 (1991) 1861-1867
44. Walsh B.W., Schiff I., Rosner B., et al. Effects of postmenopausal estrogen replacement on the concentrations and metabolism of plasma lipoproteins. N Engl J Med 325 17 (1991) 1196-1204
45. Bush T.L., Barrett-Connor E., Cowan L.D., et al. Cardiovascular mortality and noncontraceptive use of estrogen in women: results from the Lipid Research Clinics Program Follow-up Study. Circulation 75 6 (1987) 1102-1109
46. Dusting G.J., Fennessy P., Yin Z.L., et al. Nitric oxide in atherosclerosis: vascular protector or villain?. Clin Exp Pharmacol Physiol Suppl 25 (1998) S34-S41
47. Moncada S., and Higgs A. The L-arginine-nitric oxide pathway. N Engl J Med 329 (1993) 2002-2012
48. Celermajer D.S. Endothelial dysfunction: does it matter? Is it reversible?. J Am Coll Cardiol 30 (1997) 325-333
49. Anderson T.J., Uehata A., Gerhard M.D., et al. Close relation of endothelial function in the human coronary and peripheral circulations. J Am Coll Cardiol 26 (1995) 1235-1241
50. Schachinger V., Britten M.B., and Zeiher A.M. Prognostic impact of coronary vasodilator dysfunction on adverse long- term outcome of coronary heart disease. Circulation 101 16 (2000) 1899-1906
51. Perregaux D., Chaudhuri A., Mohanty P., et al. Effect of gender differences and estrogen replacement therapy on vascular reactivity. Metabolism 48 2 (1999) 227-232
52. Lieberman E.H., Gerhard M.D., Uehata A., et al. Estrogen improves endothelium-dependent, flow-mediated vasodilation in postmenopausal women. Ann Intern Med 121 (1994) 936-941
53. Rossouw J.E., Anderson G.L., Prentice R.L., et al. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial. JAMA 288 3 (2002) 321-333
54. Celermajer D.S. Testing endothelial function using ultrasound. J Cardiovasc Pharmacol 32 Suppl 3 (1998) S29-S32
55. Celermajer D.S., Sorensen K.E., Gooch V.M., et al. Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis. Lancet 340 8828 (1992) 1111-1115
56. Hashimoto M., Akishita M., Eto M., et al. Modulation of endothelium-dependent flow-mediated dilatation of the brachial artery by sex and menstrual cycle. Circulation 92 12 (1995) 3431-3435
57. Hoch A.Z., Dempsey R.L., Carrera G.F., et al. Is there an association between athletic amenorrhea and endothelial cell dysfunction?. Med Sci Sports Exerc 35 3 (2003) 377-383
58. Rickenlund A., Eriksson M.J., Schenck-Gustafsson K., et al. Amenorrhea in female athletes is associated with endothelial dysfunction and unfavorable lipid profile. J Clin Endocrinol Metab 90 3 (2005) 1354-1359
59. Rickenlund A., Eriksson M.J., Schenck-Gustafsson K., et al. Oral contraceptives improve endothelial function in amenorrheic athletes. J Clin Endocrinol Metab 90 6 (2005) 3162-3167
60. Verhaar M.C., Wever R.M., Kastelein J.J., et al. Effects of oral folic acid supplementation on endothelial function in familial hypercholesterolemia: a randomized placebo-controlled trial. [in process citation]. Circulation 100 (1999) 335-338
61. Stroes E.S., van Faassen E.E., Yo M., et al. Folic acid reverts dysfunction of endothelial nitric oxide synthase. Circ Res 86 (2000) 1129-1134
62. Hoch A.Z., Adams B., Syed A.Q., et al. Folic acid supplementation improves endothelial function in eumenorrheic runners. Med Sci Sports Exerc 37 5 (2005) S52