Genetic relationship of a Mexican Afromestizo population through the analysis of the 3′ haplotype of the β globin gene in βA chromosomes

Blood Cells, Molecules, and Diseases

Volumn 39, Issue 2, 2007, Pages 169-177

  Magaña, María Teresa ^a   Perea, F Javier ^a   González, Juan Ramón ^a   Ibarra, Bertha ^a  

^a UNIVERSITY OF GUADALAJARA   (Mexico)

Author keywords

A globin gene haplotypes; (AT)xTy repeats; 3 haplotypes; Mexican Afromestizos; Neutrality tests

Indexed keywords

BETA GLOBIN;

ARTICLE; CENTRAL AFRICAN REPUBLIC; CHROMOSOME ANALYSIS; COMPUTER PROGRAM; GAMBIA; GENETIC DISTANCE; GENETIC VARIABILITY; HAPLOTYPE; HISPANIC; HUMAN; MAJOR CLINICAL STUDY; MEXICO; NEGRO; NUCLEOTIDE SEQUENCE; POPULATION GENETICS; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; VANUATU;

AFRICAN CONTINENTAL ANCESTRY GROUP; ASIAN CONTINENTAL ANCESTRY GROUP; CHROMOSOMES, HUMAN; DNA MUTATIONAL ANALYSIS; EPIDEMIOLOGY, MOLECULAR; GLOBINS; HAPLOTYPES; HUMANS; MEXICO; POLYMORPHISM, GENETIC; POPULATION GROUPS; VARIATION (GENETICS);

EID: 34547206084     PISSN: 10799796     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcmd.2007.03.004     Document Type: Article

References (20)

1. Chakravarti A., Buetow K.H., Antonarakis S.E., et al. Nonuniform recombination within the human beta-globin gene cluster. Am. J. Hum. Genet. 36 (1984) 1239-1258
2. Antonarakis S.E., Boehm C.D., Giardina P.J., and Kazazian H.H.J. Nonrandom association of polymorphic restriction sites in the beta globin gene cluster. Proc. Natl. Acad. Sci. U. S. A. 79 (1982) 137-141
3. Fullerton S.M., Harding R.M., Boyce A.J., et al. Molecular and population genetic analysis of allelic sequence diversity at the human b-globin locus. Proc. Natl. Acad. Sci. U. S. A. 91 (1994) 1805-1809
4. Harding R.M., Fullerton S.M., Griffiths R.C., and Clegg J.B. Archaic African and Asian lineages in the genetic ancestry of modern humans. Am. J. Hum. Genet. 60 (1997) 772-789
5. Chebloune Y., Pagnier J., Trabuchet G., et al. Structural analysis of the 5′ flanking region of the beta-globin gene in African sickle cell anemia patients: further evidence for three origins of the sickle cell mutation in Africa. Proc. Natl. Acad. Sci. U. S. A. 85 (1988) 4431-4435
6. Tadmouri G.O., Garguier N., Demont J., et al. History and origin of beta-thalassemia in Turkey: sequence haplotype diversity of beta-globin genes. Hum. Biol. 73 (2001) 661-674
7. Magaña M.T., Perea F.J., Ongay Z., and Ibarra B. 3′ haplotypes of the beta-globin gene in beta(S)-chromosomes of Mexican individuals. Blood Cells Mol. Dis. 34 (2005) 48-52
8. Varawalla N.Y., Fitches A.C., and Old J.M. Analysis of β-globin gene haplotypes in Asian Indians: origin and spread of β-thalassaemia on the Indian subcontinent. Hum. Genet. 90 (1992) 443-449
9. Watterson G.A. The homozygosity test of neutrality. Genetics 88 (1978) 405-417
10. Chakraborty R. Mitochondrial DNA polymorphism reveals hidden heterogeneity within some Asian populations. Am. J. Hum. Genet. 47 (1990) 87-94
11. Tajima F. Statistical method for testing the neutral mutation hypothesis by DNA polymorphism. Genetics 123 (1989) 585-595
12. Fu Y.X. Statistical tests of neutrality of mutations against population growth, hitchhiking and background selection. Genetics 147 (1997) 915-925
13. Excoffier L., Laval G., and Schneider S. Arlequin ver. 3.0: an integrated software package for population genetics data analysis. Evolutionary Bioinform. Online (2005)
14. Smith R.A., Ho P.J., Clegg J.B., et al. Recombination breakpoints in the human beta globin gene cluster. Blood 92 (1998) 4415-4421
15. A genes in a Mexican population with African roots. Blood Cells Mol. Dis. 28 (2002) 121-126
16. Flint J., Harding R.M., Boyce A.J., et al. The population genetics of the haemoglobinopathies. In: Rodgers C.P. (Ed). Sickle Cell Disease and Thalassaemia (1998), Baillière Tindall, London 1-51
17. Wall J.D., and Przeworski M. When did the Human population size start increasing?. Genetics 155 (2000) 1865-1874
18. B. Grunberg, El universo de los conquistadores: resultado de una Investigación prosopográfica. Signos Históricos, Julio-diciembre, número 012. Universidad Autónoma Metropolitana-Iztapalapa. Distrito Federal, México. pp. 94-118.
19. Aguirre G. La población negra de México vol. II (1989), Fondo de cultura económica, SA de CV, México
20. J.D. Fage, A History of Africa, fourth ed, Routledge, 2001, http://www.atlapedia.com/online/countries/vanuatu.htm, http://condor.depaul.edu/dialogo/back_issues/issue_5/mexico_slave_trade.htm.