Urukthapelstatin A, a novel cytotoxic substance from marine-derived Mechercharimyces asporophorigenens YM11-542: I. Fermentation, isolation and biological activities

Journal of Antibiotics

Volumn 60, Issue 4, 2007, Pages 251-255

  Matsuo, Yoshihide ^a   Kanoh, Kaneo ^a   Yamori, Takao ^b   Kasai, Hiroaki ^a   Katsuta, Atsuko ^a   Adachi, Kyoko ^a   Shin ya, Kazuo ^c   Shizuri, Yoshikazu ^a  

^a MARINE BIOTECHNOLOGY INSTITUTE   (Japan)

^b CANCER CHEMOTHERAPY CENTER   (Japan)

^c NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

Author keywords

Cyclic peptide; Cytotoxic; Thermoactinomyces; Urukthapelstatin A

Indexed keywords

ANTINEOPLASTIC AGENT; CYTOTOXIC AGENT; MECHERCHARSTATIN; TELOMERASE; UNCLASSIFIED DRUG; URUKTHAPELSTATIN A; YM 11 542; YM 216391; ANTINEOPLASTIC ANTIBIOTIC; DRUG DERIVATIVE; LEUCINE; THIAZOLE DERIVATIVE;

ANTIMICROBIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; BACTERIAL STRAIN; BIOLOGICAL ACTIVITY; CANCER CELL CULTURE; CHROMATOGRAPHY; CONTROLLED STUDY; CYTOTOXICITY; DRUG DECOMPOSITION; DRUG ISOLATION; DRUG STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; MECHERCHARIMYCES ASPOROPHORIGENENS; PRIORITY JOURNAL; SOLVENT EXTRACTION; THERMOACTINOMYCES; BIOSYNTHESIS; FERMENTATION; GRAM POSITIVE BACTERIUM; ISOLATION AND PURIFICATION; METABOLISM; MICROBIOLOGY; TUMOR CELL LINE;

BACTERIA (MICROORGANISMS); THERMOACTINOMYCES; THERMOACTINOMYCETACEAE;

ANTIBIOTICS, ANTINEOPLASTIC; CELL LINE, TUMOR; FERMENTATION; GRAM-POSITIVE ENDOSPORE-FORMING BACTERIA; HUMANS; LEUCINE; THIAZOLES; WATER MICROBIOLOGY;

EID: 34547184566     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.1038/ja.2007.30     Document Type: Article

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