TORC2 regulates germinal center repression of the TCL1 oncoprotein to promote B cell development and inhibit transformation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 24, 2007, Pages 10175-10180

  Kuraishy, Ali I ^a   French, Samuel W ^a   Sherman, Mara ^a   Herling, Marco ^b   Jones, Dan ^b   Wall, Randolph ^a   Teitell, Michael A ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Gene regulation; Lymphomagenesis; Signal transduction

Indexed keywords

B LYMPHOCYTE RECEPTOR; BUCLADESINE; COMPLEMENTARY DNA; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; IMMUNOGLOBULIN M ANTIBODY; MESSENGER RNA; MUTANT PROTEIN; ONCOPROTEIN; SMALL INTERFERING RNA; TCL1 ONCOPROTEIN; TORC2 PROTEIN; TRANSDUCER OF REGULATED CREB PROTEIN; UNCLASSIFIED DRUG; CRTC2 PROTEIN, HUMAN; TCL1A PROTEIN, HUMAN; TRANSCRIPTION FACTOR;

APOPTOSIS; ARTICLE; B CELL LYMPHOMA; B LYMPHOCYTE; CARCINOGENESIS; CELL STRAIN HEK293; CELL TRANSFORMATION; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; GENE EXPRESSION REGULATION; GENE REPRESSION; GENE SILENCING; GERMINAL CENTER; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOHISTOCHEMISTRY; LEUKEMIA CELL LINE; NORTHERN BLOTTING; PRIORITY JOURNAL; REPORTER GENE; RETROVIRUS; RNA ANALYSIS; SIGNAL TRANSDUCTION; BIOLOGICAL MODEL; CELL LINE; GENE VECTOR; GENETICS; IMMUNOLOGY; METABOLISM; PATHOLOGY; PLASMID; TUMOR CELL LINE;

APOPTOSIS; B-LYMPHOCYTES; CELL LINE; CELL LINE, TUMOR; CELL TRANSFORMATION, NEOPLASTIC; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC VECTORS; GERMINAL CENTER; HUMANS; JURKAT CELLS; MODELS, BIOLOGICAL; PLASMIDS; PROTO-ONCOGENE PROTEINS; RETROVIRIDAE; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

EID: 34547145931     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0704170104     Document Type: Article

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