Platelet activating factor receptors drive CXC chemokine production, neutrophil influx and edema formation in the lungs of mice injected with Tityus serrulatus venom

Toxicon

Volumn 50, Issue 3, 2007, Pages 420-427

  Coelho, Fernanda Matos ^a   Pessini, Andréa C ^a,b   Coelho, Amanda M ^a   Pinho, Vanessa S ^a   Souza, Danielle G ^a   Arantes, Eliane C ^b   Teixeira, Mauro M ^a   Teixeira, Antônio L ^a  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

CXCR2 inhibitor; Lung edema; PAF receptor antagonist; Tityus serrulatus

Indexed keywords

ALPHA CHEMOKINE; CHEMOKINE RECEPTOR ANTAGONIST; CHEMOKINE RECEPTOR CXCR2; DYE; EVANS BLUE; MODIPAFANT; MYELOPEROXIDASE; REPERTAXIN; SCORPION VENOM; THROMBOCYTE ACTIVATING FACTOR; THROMBOCYTE ACTIVATING FACTOR ANTAGONIST; THROMBOCYTE ACTIVATING FACTOR RECEPTOR; TITYUS TOXIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL PERMEABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENVENOMATION; ENZYME ACTIVITY; EXTRAVASATION; LETHALITY; LUNG EDEMA; LUNG INJURY; MALE; MOUSE; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; SCORPION; TITYUS SERRULATUS;

ANIMALS; CHEMOKINES, CXC; DIHYDROPYRIDINES; DOSE-RESPONSE RELATIONSHIP, DRUG; EDEMA; GRANULOCYTE COLONY STIMULATING FACTOR, RECOMBINANT; IMIDAZOLES; INTERLEUKIN-3; LUNG DISEASES; MALE; MICE; NEUTROPHILS; PLATELET MEMBRANE GLYCOPROTEINS; RECEPTORS, G-PROTEIN-COUPLED; RECOMBINANT FUSION PROTEINS; SCORPION VENOMS; SCORPIONS; SULFONAMIDES; TIME FACTORS;

MUS; SCORPIONES; TITYUS SERRULATUS;

EID: 34547130828     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2007.04.009     Document Type: Article

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