P53 expression between 13-27 weeks old human male fetus gonads

Journal of Molecular Histology

Volumn 38, Issue 4, 2007, Pages 271-274

  Tosun, Murat ^a   Tosun, Emine ^b   Kalkan, Serpil ^c   Avunduk, Mustafa Cihat ^c  

^a AFYON KOCATEPE UNIVERSITY   (Turkey)

^b BASKENT UNIVERSITY   (Turkey)

^c SELCUK UNIVERSITY   (Turkey)

Author keywords

Development; Embryology; Fetus; P53; Spermatogonia

Indexed keywords

PROTEIN P53;

ARTICLE; FETUS; GONAD; HUMAN; IMMUNOHISTOCHEMISTRY; MALE; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SECOND TRIMESTER PREGNANCY; SEMINIFEROUS TUBULE; SPERMATOGONIUM; STAINING; TESTIS;

FEMALE; FETUS; HUMANS; MALE; PREGNANCY; PREGNANCY TRIMESTER, FIRST; PREGNANCY TRIMESTER, SECOND; SEMINIFEROUS TUBULES; SPERMATOGONIA; TESTIS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 34547121183     PISSN: 15672379     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10735-007-9097-2     Document Type: Article

References (16)

1. Allemand I, Anglo A, Jeantet AY et al (1999) Testicular wild type p53 expression in transgenic mice induces spermiogenesis alterations ranging from differentiation defects to apoptosis. Oncogene 18(47):6521-6530
2. Bartkova J, Falck J, Rajpert-De Meyts E et al (2001) Chk2 tumor suppressor protein in human spermatogenesis and testicular germ-cell tumors. Oncogene 20(41):5897-5902
3. Beumer TL, Roepers-Gajadien HL, Gademan IS et al (2000) Apoptosis regulation in the testis: involvement of Bcl-2 family members. Mol Reprod Dev 56(3):353-359
4. Beumer TL, Roepers-Gajadien HL, Gademan IS et al (1998) The role of the tumor suppressor p53 in spermatogenesis. Cell Death Differ 5(8):669-677
5. Boekelheide K (2005) Mechanisms of toxic damage to spermatogenesis. J Natl Cancer Inst Monogr 34:6-8
6. Cheung KJ Jr, Li G (2001) Tissue-specific regulation of Chk1 expression by p53. Exp Mol Pathol 71(2):156-160
7. Chin MY, Li G (2003) Tissue-specific regulation of checkpoint kinase 2 expression by p53. Exp Mol Pathol 75(2):131-136
8. Choi J, Nannenga B, Demidov ON et al (2002) Mice deficient for the wild-type p53-induced phosphatase gene (Wip1) exhibit defects in reproductive organs, immune function, and cell cycle control. Mol Cell Biol 22(4):1094-1105
9. Donehower LA, Harvey M, Slagle BL et al (1992) Mice deficient for p53 is developmentally normal but susceptible to spontaneous tumors. Nature 356:215-221
10. Embree-Ku M, Venturini D, Boekelheide K (2002) Fas is involved in the p53-dependent apoptotic response to ionizing radiation in mouse testis. Biol Reprod 66(5):1456-1461
11. Fujisawa M, Shirakawa T, Fujioka H et al (2001) Adenovirus-mediated p53 gene transfer to rat testis impairs spermatogenesis. Arch Androl 46(3):223-231
12. Helal MA, Mehmet H, Thomas NSB et al (2002) Ontogeny of human fetal testicular apoptosis during first, second, and third trimesters of pregnancy. J Clin Endocrinol Metab 87:1189-1193
13. Hupp TR, Sparks A, Lane DP (1995) Small peptides activate the latent sequence-specific DNA binding function of p53. Cell 83:237-245
14. Levine AJ (1997) p53, the cellular gatekeeper for growth and division. Cell 88:323-331
15. Sasagawa I, Yazawa H et al (2001) Stress and testicular germ cell apoptosis. Arch Androl 47(3):211-216
16. Yin Y, Stahl BC, DeWolf WC et al (1998) p53-mediated germ cell quality control in spermatogenesis. Dev Biol 204(1):165-171