Role of plasma DNA as a predictive marker of fatal outcome following severe head injury in males

Journal of Neurotrauma

Volumn 24, Issue 7, 2007, Pages 1172-1181

  Yurgel, Virginia Campello ^a   Ikuta, Nilo ^a,b   Da Rocha, Adriana Brondani ^a   Lunge, Vagner Ricardo ^a,b   Schneider, Rogerio Fett ^a,c   Fonseca, André Salvador Kazantzi ^b   Grivicich, Ivana ^a   Zanoni, Caroline ^a   Regner, Andrea ^a,c  

^a UNIVERSIDADE LUTERANA DO BRASIL   (Brazil)

^b Simbios Biotecnologia   (Brazil)

^c Hospital de Pronto Socorro   (Brazil)

Author keywords

Plasma DNA; Prognostic marker; Real time PCR; Traumatic brain injury

Indexed keywords

BETA GLOBIN; DNA;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DNA DETERMINATION; HEAD INJURY; HUMAN; INJURY SEVERITY; MALE; MORTALITY; PROGNOSIS; REAL TIME POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; SURVIVAL; TRAUMATIC BRAIN INJURY;

ADOLESCENT; ADULT; BIOLOGICAL MARKERS; BRAIN INJURIES; CRANIOCEREBRAL TRAUMA; DNA; GLOBINS; HUMANS; MALE; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; PROGNOSIS; SEX FACTORS; SURVIVAL RATE; UP-REGULATION;

EID: 34547120181     PISSN: 08977151     EISSN: None     Source Type: Journal    
DOI: 10.1089/neu.2006.0160     Document Type: Article

References (44)

1. BALESTRERI, M., CZOSNYKA, M., CHATFIELD, D.A., et al. (2004). Predictive value of Glasgow Coma Scale after brain trauma: change in trend over the past ten years. J. Neurol. Neurosurg. Psychiatr. 75, 161-162.
2. BASSO, A., PREVIGLIANO, I., DUARTE, J.M., and FERRARI, N. (2001). Advances in management of neurosurgical trauma in different continents. World J. Surg. 25, 1174-1178.
3. BOOM, R., SOL, C.J.A., SALIMANS, M.M.M., et al. (1990). Rapid and simple method for purification of nucleic acids. J. Clin. Microbiol. 28, 495-503.
4. CHO, D.Y., and WANG, Y.C. (1997). Comparison of the APACHE III, APACHE II and Glasgow Coma Scale in acute head injury for prediction of mortality and functional outcome. Intensive Care Med. 23, 77-84.
5. COPLIN, W. (2001). Intracranial pressure and surgical decompression for traumatic brain injury: biological rationale and protocol for a randomized clinical trial. Neurol. Res. 23, 277-290.
6. DA ROCHA, A.B., ZANONI, C., DE FREITAS, G.R., et al. (2005). Serum Hsp70 as an early predictor of fatal outcome after severe traumatic brain injury in males. J. Neurotrauma 22, 966-977.
7. DA ROCHA, A.B., SCHNEIDER, R.F., DE FREITAS, G.R., et al. (2006). Role of serum S100B as a predictive marker of fatal outcome Following isolated severe head injury or multitrauma in males. Clin. Chem. Lab. Med. 44, 1234-1242.
8. DIMOPOULOU, I., KORFIAS, S., DAFNI, U., et al. (2003). Protein S-100b serum levels in trauma-induced brain death. Neurology 60, 947-951.
9. FACKELMAYER, F.O., HESCH, R.D., JAHR, S., et al. (2001). DNA fragments in the blood plasma of cancer patients: quantitations and evidence for their origin from apoptotic and necrotic cells. Cancer Res. 61, 1659-1665.
10. FINFER, S.R., and COHEN, J. (2001). Severe traumatic brain injury. Resuscitation 48, 77-90.
11. GENNARELLI, T.A. (1993). Mechanisms of brain injury. J. Emerg. Med. 11, 5-11.
12. GHAJAR, J. (2000). Traumatic brain injury. Lancet 356, 923-929.
13. HEID, C.A., STEVENS, J., LIVAK, K.J., and WILLIAMS, P.M. (1996). Real-time quantitative PCR. Genome Res. 6, 986-994.
14. HERRMANN, M., CURIO, N., JOST, S., et al. (2001). Release of biochemical markers of damage to neuronal and glial brain tissue is associated with short and long term neuropsychological outcome after traumatic brain injury. J. Neurol. Neurosurg. Psychiatr. 70, 95-100.
15. HOLLAND, P.M., ABRAMSON, R.D., WATSON, R., and GELFAND, D.H. (1991). Detection of specific polymerase chain reaction product by utilizing the 5′-3′ exonuclease activity of Thermus aquaticus DNA polymerase. Proc. Natl. Acad. Sci. U.S.A. 88, 7276-7280.
16. JARRAR, D., WANG, P., CIOFFI, W.G., BLAND, K.I., and CHAUDRY, I.H. (2000). The female reproductive cycle is an important variable in the response to trauma-hemorrhage. Am. J. Physiol. Heart Circ. Physiol. 279, 1015-1021.
17. JENNETT, B. (1998). Epidemiology of head injury. Arch. Dis. Child. 78, 403-406.
18. JOHNSON, P.J., and LO Y.M.D. (2002). Plasma nucleic acids in the diagnosis and management of malignant disease. Clin. Chem. 48, 1186-1193.
19. LAI, Y.C., CHEN, F.G., GOH, M.H. and KOH, K.F. (1998). Predictors of long-term outcome in severe head injury. Ann. Acad. Med. Singap. 27, 326-331.
20. LAM, N.Y.L., RAINER, T.H., CHAN, L.Y.S., JOYNT, G.M. and LO, Y.M.D. (2003). Time course of early and late changes in plasma DNA in trauma patients. Clin. Chem. 49, 1286-1291.
21. LAM, N.Y.L., RAINER, T.H., CHIU, R.W.K., JOYNT, G.M., and LO, Y.M.D. (2004). Plasma mitochondrial DNA concentrations after trauma. Clin. Chem. 50, 213-216.
22. LEONE, M., ALBANESE, J., ROUSSEAU, S., et al. (2003). Pulmonary contusion in severe head trauma patient: impact on gas exchange and outcome. Chest 124, 2261-2266.
23. LO, Y.M.D., CORBETTA N., CHAMBERLAIN P.F., et al. (1997). Presence of fetal DNA in maternal plasma and serum. Lancet 350, 485-487.
24. LO, Y.M.D., RAINER, T.H., CHAN, L.Y.S., HJELM, N.M., and COCKS, R.A. (2000). Plasma DNA as a prognostic marker in trauma patients. Clin. Chem. 46, 319-323.
25. LO, Y.M.D., TEIN, M.S.C., LAU, T.K., et al. (1998a). Quantitative analysis of fetal DNA in maternal plasma and serum: implications for noninvasive prenatal diagnosis. Am. J. Hum. Genet. 62, 768-775.
26. LO, Y.M.D., TEIN, M.S.C, PANG, C.C., YEUNG, C.K., TONG, K.L., and HJELM, N.M. (1998b). Presence of donor-specific DNA in plasma of kidney and liver transplant recipients. Lancet 351, 1329-1330.
27. LO, Y.M.D., ZHANG, J., LEUNG, T.N., LAU, T.K., CHANG, A.M.Z., and HJELM, N.M. (1999). Rapid clearance of fetal DNA from maternal plasma. Am. J. Hum. Genet. 64, 218-224.
28. MARION, D.W., and CARLIER, P.M. (1994). Problems with initial Glasgow Coma Scale assessment caused by prehospital treatment of patients with head injuries: results of a national survey. J. Trauma 36, 89-95.
29. MUSSACK, T., BIBERTHALER, P., KANZ, K., et al. (2002). Serum S-100B and interleukin-8 as predictive markers for comparative neurologic outcome analysis of patients after cardiac arrest and severe traumatic brain injury. Crit. Care Med. 30, 2669-2674.
30. NAVRATIL, O., SMRCKA, M., and HANAK, P. (2006). The outcome, working ability and psychic changes after traumatic brain injury. Bratisl. Lek. Listy. 107, 110-112.
31. PETZOLD, A., GREEN, A.J.E., KEIR, G., et al. (2002). Role of serum S100B as an early predictor of high intracranial pressure and mortality in brain injury: a pilot study. Crit. Care Med. 30, 2705-2710.
32. RAABE, A., GROLMS, C., SORGE, O., ZIMMERMANN, M., and SEIFERT, V. (1999). Serum S-100B protein in severe head injury. Neurosurgery 45, 477-483.
33. RAABE, A., KOPETSCH, O., WOSZCZYK, A., LANG, J., and GERLACH, R. (2003). Serum S100B protein as a molecular marker in severe traumatic brain injury. Restor. Neurol. Neurosci. 21, 159-169.
34. RAINER, T.H., WONG, L.K.S., LAM, W., et al. (2003). Prognostic use of circulating plasma nucleic acid concentrations in patients with acute stroke. Clin. Chem. 49, 562-569.
35. REGNER, A., KAUFMAN, M., FRIEDMAN, G., and CHEMALE, I. (2001). Increased serum S100fl protein concentrations following severe head injury in humans: a biochemical marker of brain death? Neuroreport 12, 691-694.
36. ROTHOERL, R.D., WOERTGEN, C., HOLZSCHUH, M., METZ, C., and BRAWANSKI, A. (1999). Rapid evaluation of S-100 serum levels. Case report and comparison to previous results. Brain Inj. 13, 387-391.
37. ROOF, R.L., and HALL, E.D. (2000). Gender differences in acute CNS trauma and stroke: neuroprotective effects of estrogen and progesterone. J. Neurotrauma 17, 367-388.
38. SAVOLA, O., PYHTINEN, J., LEINO, T.K., SIITONEN, S., NIEMELA, O., and HILLBOM, M. (2004). Effects of head and extracranial injuries on serum protein S100B levels in trauma patients. J. Trauma 56, 1229-1234.
39. TOWNEND, W.J., GUY, M.J., PANI, M.A., MARTIN, B., and YATES, D.W. (2002). Head injury outcome prediction in the emergency department: a role for protein S-100B? J. Neurol. Neurosurg. Psychiatr. 73, 542-546.
40. WANG, B.G., HUANG, H., CHEN, Y., et al. (2003). Increased plasma DNA integrity in cancer patients. Cancer Res. 63, 3966-3968.
41. WIJERATNE, S., BUTT, A., BURNS, S., SHERWOOD, K., BOYD, O., and SWAMINATHAN, R. (2004). Cell-free plasma DNA as a prognostic marker in intensive treatment unit patients. Ann. N.Y. Acad. Sci. 1022, 323-328.
42. WILSON, J.T.L., PETTIGREW, L.E.L., and TEASDALE, G.M. (1998). Structured Interviews for the Glasgow Outcome Scale and the Extended Glasgow Outcome Scale: guidelines for their use. J. Neurotrauma 15, 573-585.
43. ZAGARA, G., SCARAVILLI, P., MASTORGIO, P., and SEVESO, M. (1992). Validation of a prognostic system in severely brain-injured patients. J. Neurosurg. Sci. 35, 77-81.
44. ZEMLAN, F.P., JAUCHB, E.C., MULCHAHEYA, J., et al. (2002). C-tau biomarker of neuronal damage in severe brain injured patients: association with elevated intracranial pressure and clinical outcome. Brain Res. 947, 131-139.