A model for the induction of DNA damages by fast neutrons and their evolution into cell clonogenic inactivation

Journal of Radiation Research

Volumn 48, Issue 4, 2007, Pages 289-303

  Yamaguchi, Hiroshi ^a   Waker, Anthony J ^b  

^a NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

^b UNIVERSITY OF ONTARIO INSTITUTE OF TECHNOLOGY   (Canada)

Author keywords

DNA damage; Inactivation cross section; Model; Neutron; Radiation mechanism

Indexed keywords

ATOMS; CHARGED PARTICLES; DNA; NEUTRON IRRADIATION; SPECTROSCOPY;

CELLULARS; CLONOGENICS; DNA DAMAGES; DNA MOLECULES; ENERGY DEPOSITIONS; ENERGY SPECTRUM; FAST NEUTRONS; INACTIVATION CROSS SECTION; RADIATION MECHANISM; RADIATION QUALITY;

NEUTRONS;

EID: 34547114737     PISSN: 04493060     EISSN: 13499157     Source Type: Journal    
DOI: 10.1269/jrr.06107     Document Type: Article

References (34)

1. Leenhouts, H. P. and Chadwick, K. H. (1974) A theoretical analysis of radiation sensitivity of in cells following neutron irradiation, Proceedings of a Symposium "Biological Effects of Neutron Irradiation", pp.151-161, International Atomic Energy Agency, Vienna, STI/PUB/352.
2. Lea, D, F. (1955) Action of Radiations in Living Cells, Cambridge University Press.
3. Dertinger, H. and Jung, H. (1969) Molecular Radiation Biology, Springer-Verlag, Berlin.
4. Bewley, D. K., McNally, N. J. and Page, B. C. (1974) The biological effect of fast neutrons not in charged-particle equilibrium, Proceedings of a Symposium "Biological Effects of Neutron Irradiation", pp.97-106, International Atomic Energy Agency, Vienna, STI/PUB/352.
5. Broerse, J. J., Barendsen, G. W. and van Kersen, G. R. (1968) Survival of cultured human cells after irradiation with fast neutrons of different energies in hypoxic and oxygenated conditions, Int. J. Radiat. Biol. 13: 559-572.
6. Todd, P. W. (1967) Heavy-ion irradiation of cultured human cells. Radiat. Res. Suppl. 7: 196-207.
7. Barendsen, G. W. (1968) Responses of cultured cells, tumors and normal tissues to radiation of different linear energy transfer. In Current Topics in Radiation Research, vol.4 (Eds. M. Ebert and A. Howard Eds.) , pp.295-356.
8. Munson, R. J., Bance, D. A., Stretch, A. and Goodhead, D. T. (1979) Mutation and inactivation of cultured mammalian cells exposed to beams of accelerated heavy ions. Int. J. Radiat. Biol. 36: 127-136.
9. Blakely, E. Tobias, C. A., Yang, T. C. H., Smith, K. C. and Lyman, J. T. (1979) Inactivation of human kidney cells by high-energy monoenergetic heavy-ion beams. Radiat. Res. 80: 122-160.
10. Goodhead, D. T., Munson, R. J., Thacker, J. and Cox, R. (1980) Mutation and inactivation of cultured mammalian cells exposed to beams of accelerated heavy ions IV. Biophysical interpretation. Int. J. Radiat. Biol. 37: 135-167.
11. Tobias, C. A., Blakely, L. A., Chang, P. Y., Lommel L. and Roots, R. (1984) Response of sensitive human ataxia and resistant T-1 cell lines to accelerated heavy ions. Br J Cancer Suppl. 6: 175-185.
12. Chadwick, K. H., Moschini, G. and Varma M. N. Eds. (1992) Biophysical Modeling of Radiation Effects. IOP Publishing Ltd, Bristol UK.
13. Goodhead, D. T. (1987) Relationship of microdosimetric techniques to applications in biological systems. In The dosimetry of ionizing radiation vol. II. Eds., K. R. Kase, B. E. Biarnard and F. H. Attix Eds.), pp.1-89, Academic Press New York.
14. Yamaguchi, H., Ohara, H. and Waker, A. J. (2006) A Model for the Induction of DNA damages and their Evolution into Cell Clonogenic Inactivation, J. Radiat. Res., 47: 197-211.
15. Goodhead, D. T., Belli, M., Mill, A. J., Bance, D. A., Allen, L. A., Hall, S. C., Ianzani, F., Simone, G., Stevens, D. L. Stretch, A., Tobacchini, M. A. and Wilkinson, R. E. (1992) Direct comparison between protons and alpha-particles of the same LET: I. Irradiation methods and inactivation of asynchronous V79, HeLa and C3H 101/2 cells, Int. J. Radiat. Biol. 61: 611-624.
16. Watson, J. D., Hopkins, N. H., Roberts, J. W., Steitz, J. A. and Weiner, A. M. (1987) Molecular Biology of the Gene, Forth edition, The Benjamin/Cummings Publishing Company, Inc.
17. LaVerne, J. and Pimblott, S. M. (1993) Yields of hydroxyl radical and hydrated electron scavenging reactions in aqueous solutions of biological interest, Radiat. Res., 135: 16-23.
18. Hughes, D. J. and Schwartz, H. B, (1958) Neutron cross section, BNL 325, Brookhaven National Laboratory, Upton, New York.
19. Watt, D. E. (1996) Quantities for Dosimetry of Ionizing Radiations in Liquid Water, Taylor & Francis.
20. Morikawa, K., Matsumoto, O., Tsujimoto, M., Katayanagi, K., Ariyoshi, M., Doi, T., Inaoka, T. and Ohtsuka, E. (1992) X-ray structure of T4 endonuclease V: an excision repair enzyme specific for a pyrimidine dimmer, Science, 256 (5056): 523-526.
21. Houldsworth, J., Cohen, D., Singh, S. and Lavin, M. F. (1991) The Response of Ataxia-Telangiectasia Lymphoblastoid Cells to Neutron irradiation, Radiat. Res. 125: 277-282.
22. 1/2 Mouse Cells, Radiat. Res. 117: 114-127.
23. Nias, A. H. W., Greene, D., Fox, M. and Thomas, R. L. (1967) Effect of 14 MeV monoenergetic neutrons on HeLa and P388F cells in vitro, Int. J. Radiat. Biol. 13: 449-456.
24. Berry, R. J. (1971) Hypoxic protection against of fast neutrons of different energies, A review, Er. J. Cancer 7: 145-152.
25. 2+, Radiat. Res. 93: 40-50.
26. Yamaguchi, H., Uchihori, Y., Yasuda, N., Takada, M. and Kitamura, H. (2005) Estimation of yields of OH radicals in water irradiated by ionizing radiation, J. Radiat. Res. 46: 333-341.
27. Richmond, T. J. and Davey, C. A. (2003) The structure of DNA in the nucleosome core, Nature, 423: 145-147.
28. ICRU report 26 (1972) Neutron Dosimetry for Biological and Medicine, Washington, D. C. USA.
29. Berry, R. J. (1974) Modification effects upon cells by repair, and by physical and chemical means, Proceedings of a Symposium "Biological Effects of Neutron Irradiation", pp. 257-271, International Atomic Energy Agency, Vienna, STI/PUB/352.
30. Hall, E. J., Novak, J. K., Kellerer, A. M., Rossi, H. H., Marino, S. and Goodman, L. J., (1973) RBE as a function of neutron energy, 1. Experimental observations, Radiat. Res. 64: 245-255.
31. Hall, E. J., Rossi, H. H., Kellerer, A. M., Goodman, L. J. and Marino, S. (1973) Radiobiological studies with monoenergetic neutron, Radiat. Res. 54: 431-443.
32. Hall, E. J., Roizin-Towle, L., Theus, R. B. and August, L. S. (1975) Radiobiological properties of high-energy cyclotron-produced neutrons used for radiotherapy, Radiology 117: 173-178.
33. ICRP 60 (1991) Recommendation of the International Commission on Radiological Protection, Annals of the ICRP, 21: Nos 1-3.
34. Luger, K. and Richmond, T. J. (1998) DNA binding within the nucleosome core, Curr. Opin. Struct. Biol. 8: 33-40.