Inhibition of phosphatidylinositol 3-kinase does not alter forskolin- stimulated Cl- secretion by T84 cells

American Journal of Physiology - Cell Physiology

Volumn 278, Issue 5 47-5, 2000, Pages

  Dickson, Jeffrey L ^a   Conner, Tracy D ^a   Ecay, Tom W ^a,b  

^a East Tennessee State University   (United States)

^b EAST TENNESSEE STATE UNIVERSITY   (United States)

Author keywords

Cystic fibrosis transmembrane conductance regulator; Endocytosis; Epithelia; Short circuit current; Wortmannin

Indexed keywords

CHLORIDE ION; CYCLIC AMP; FORSKOLIN; HORSERADISH PEROXIDASE; PHOSPHATIDYLINOSITOL 3 KINASE; TRANSMEMBRANE CONDUCTANCE REGULATOR; WORTMANNIN;

APICAL MEMBRANE; ARTICLE; CANCER CELL; CHLORIDE TRANSPORT; COLON CANCER; CONTROLLED STUDY; ENDOCYTOSIS; ENZYME INHIBITION; HUMAN; HUMAN CELL; MEMBRANE TRANSPORT; PRIORITY JOURNAL;

ARMORACIA RUSTICANA;

EID: 0034040567     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.2000.278.5.c865     Document Type: Article

References (12)

1. Anderson MP and Welsh MJ. Calcium and cAMP activate different chloride channels in the apical membrane of normal and cystic fibrosis epithelia. Proc Natl Acad Sci USA 88: 6003-6007, 1991.
2. Barrett KE. Integrated regulation of intestinal epithelial transport: intercellular and intracellular pathways. Am J Physiol Cell Physiol 272: C1069-C1076, 1997.
3. - secretion in T84 cells: membrane target(s) of inhibition is agonist specific. Am J Physiol Cell Physiol 274: C958-C965, 1998.
4. Bell CL and Quinton PM. Asymmetric permeabilization of an epithelium: a tool to study a single membrane in isolation. J Tissue Cult Methods 14: 165-171, 1992.
5. Biwersi J and Verkman AS. Functional CFTR in the endosomal compartment of CFTR-expressing fibroblasts and T84 cells. Am J Physiol Cell Physiol 266: C149-C156, 1994.
6. Bradbury NA. Intracellular CFTR: localization and function. Physiol Rev 79: S175-S191, 1999.
7. Bradbury NA and Bridges RJ. Role of membrane trafficking in plasma membrane solute transport. Am J Physiol Cell Physiol 267: C1-C24, 1994.
8. Bradbury NA, Clark JA, Watkins SC, Widnell CC, Smith HSIV, and Bridges RJ. Characterization of the internalization pathways for the cystic fibrosis transmembrane conductance regulator. Am J Physiol Lung Cell Mol Physiol 276: L659-L668, 1999.
9. Bradbury NA, Cohn JA, Venglarik CJ, and Bridges RJ. Biochemical and biophysical identification of cystic fibrosis transmembrane conductance regulator chloride channels as components of endocytic clathrin-coated vesicles. J Biol Chem 269: 8296-8302, 1994.
10. Bradbury NA, Jilling T, Berta G, Sorcher EJ, Bridges RJ, and Kirk KL. Regulation of plasma membrane recycling by CFTR. Science 256: 530-532, 1992.
11. Bradbury NA, Jilling T, Kirk KL, and Bridges RJ. Regulated endocytosis in a chloride secretory epithelial cell line. Am J Physiol Cell Physiol 262: C752-C759, 1992.
12. +-ATPase a subunit in response to dopamine. Mol Biol Cell 9: 1209-1220, 1998.