Oxidative biology: New intervention opportunities in psychiatry

Acta Neuropsychiatrica

Volumn 19, Issue 4, 2007, Pages 259-260

  Berk, Michael ^a,b,c  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b THE NATIONAL CENTRE OF EXCELLENCE IN YOUTH MENTAL HEALTH   (Australia)

^c FLOREY INSTITUTE OF NEUROSCIENCE AND MENTAL HEALTH   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; ALPHA TOCOPHEROL; ANTIOXIDANT; CATALASE; DOPAMINE; GLUTATHIONE; HALOPERIDOL; LITHIUM; MOOD STABILIZER; VALPROIC ACID;

ANTIOXIDANT ACTIVITY; APOPTOSIS; AUTISM; BIPOLAR DISORDER; DRUG OVERDOSE; EXTRAPYRAMIDAL SYMPTOM; GENETIC POLYMORPHISM; HUMAN; LIPID PEROXIDATION; MAJOR DEPRESSION; MANIA; MENTAL DISEASE; OXIDATION; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PSYCHOSIS; SCHIZOPHRENIA; SHORT SURVEY; STRESS; TARDIVE DYSKINESIA;

EID: 34447640019     PISSN: 09242708     EISSN: 16015215     Source Type: Journal    
DOI: 10.1111/j.1601-5215.2007.00224.x     Document Type: Short Survey

References (16)

1. Looney JM, Childs HM. The lactic acid and glutathione content of the blood of schizophrenic patients. J Clin Invest 1934 13:963 968.
2. Yao JK, Leonard S, Reddy R. Altered glutathione redox state in schizophrenia. Dis Markers 2006 22:83 93.
3. Reddy R, Keshavan M, Yao JK. Reduced plasma antioxidants in first-episode patients with schizophrenia. Schizophr Res 2003 62:205 212.
4. Kuloglu M, Ustundag B, Atmaca M et al. Lipid peroxidation and antioxidant enzyme levels in patients with schizophrenia and bipolar disorder. Cell Biochem Funct 2002 20:171 175.
5. Ozcan ME, Gulec M, Ozerol E, Polat R, Akyol O. Antioxidant enzyme activities and oxidative stress in affective disorders. Int Clin Psychopharmacol 2004 19:89 95.
6. James SJ, Cutler P, Melnyk S et al. Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism. Am J Clin Nutr 2004 80:1611 1617.
7. Zoroglu SS, Armutcu F, Ozen S et al. Increased oxidative stress and altered activities of erythrocyte free radical scavenging enzymes in autism. Eur Arch Psychiatry Clin Neurosci 2004 254:143 147.
8. Chauhan A, Chauhan V, Brown WT, Cohen I. Oxidative stress in autism: increased lipid peroxidation and reduced serum levels of ceruloplasmin and transferring - the antioxidant proteins. Life Sci 2004 75:2539 2549.
9. Sogut S, Zoroglu SS, Ozyurt H et al. Changes in nitric oxide levels and antioxidant enzyme activities may have a role in the pathophysiological mechanisms involved in autism. Clin Chim Acta 2003 331:111 117.
10. Bilici M, Efe H, Koroglu MA et al. Antioxidative enzyme activities and lipid peroxidation in major depression: alterations by antidepressant treatments. J Affect Disord 2001 64:43 51.
11. Harada S, Tachikawa H, Kawanishi Y. Glutathione S-transferase M1 gene deletion may be associated with susceptibility to certain forms of schizophrenia. Biochem Biophys Res Commun 2001 281:267 271.
12. Parikh V, Khan MM, Mahadik SP. Differential effects of antipsychotics on expression of antioxidant enzymes and membrane lipid peroxidation in rat brain. J Psychiatr Res 2003 37:43 51.
13. Shao L, Young LT, Wang JF. Chronic treatment with mood stabilizers lithium and valproate prevents excitotoxicity by inhibiting oxidative stress in rat cerebral cortical cells. Biol Psychiatry 2005 58:879 884.
14. Do KQ, Trabensinger MK, Lauer CJ et al. Schizophrenia: glutathione deficit in cerebrospinal fluid and prefrontal cortex in vivo. Eur J Neurosci 2000 12:3721 3728.
15. Reddy RD, Yao JK. Free radical pathology in schizophrenia: a review. Prostaglandins Leukot Essent Fatty Acids 1996 55:33 43.
16. Larowe SD, Mardikian P, Malcolm R et al. Safety and tolerability of N-acetylcysteine in cocaine-dependent individuals. Am J Addict 2006 15:105 110.