Isosteric probes provide structural requirements essential for detoxification of the phytoalexin brassinin by the fungal pathogen Leptosphaeria maculans

Bioorganic and Medicinal Chemistry

Volumn 15, Issue 18, 2007, Pages 6054-6061

  Pedras, M Soledade C ^a   Jha, Mukund ^a   Minic, Zoran ^a   Okeola, Oladapo G ^a  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

Author keywords

Brassinin; Brassinin oxidase; Leptosphaeria maculans; Paldoxin; Phoma lingam; Phytoalexin; Phytoalexin detoxification inhibitor

Indexed keywords

ANTIFUNGAL AGENT; BRASSININ; CARBAMIC ACID; CROP PROTECTION AGENT; DITHIOCARBAMIC ACID DERIVATIVE; ETHYL N' (3 INDOLYLMETHYL)DITHIOCARBAMATE; N' METHYLBRASSININ; OXIDOREDUCTASE; PALDOXIN; PHYTOALEXIN; PHYTOALEXIN DETOXIFICATION INHIBITOR; PROPYL N' (3 INDOLYLMETHYL)DITHIOCARBAMATE; THIOUREA; UNCLASSIFIED DRUG; UREA;

ANTIFUNGAL ACTIVITY; ARTICLE; BIOASSAY; BRASSICA; CHEMICAL STRUCTURE; CROP PROTECTION; DETOXIFICATION; ENZYME ACTIVITY; ENZYME SPECIFICITY; ENZYME SUBSTRATE; FUNGUS; FUNGUS CULTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LEPTOSPHAERIA MACULANS; METABOLITE; NONHUMAN; PLANT DEFENSE; PLANT FUNGUS INTERACTION; PLANT PATHOGEN INTERACTION;

ANTIFUNGAL AGENTS; ASCOMYCOTA; BRASSICACEAE; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; INDOLES; METABOLIC DETOXICATION, DRUG; PLANT DISEASES; PLANT EXTRACTS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; THIOCARBAMATES;

BRASSICA; FUNGI; LEPTOSPHAERIA MACULANS;

EID: 34447635080     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2007.06.040     Document Type: Article

References (19)

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2. Pedras M.S.C., Zheng Q.A., and Sarma-Mamillapalle V.K. Nat. Prod. Comm. 2 (2007) 319
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18. Pedras, M. S. C.; Minic, Z., in preparation.
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