메뉴 건너뛰기




Volumn 189, Issue 1-2, 2007, Pages 111-117

Isolation and functional characterization of anti-acetylcholine receptor subunit-specific autoantibodies from myasthenic patients: Receptor loss in cell culture

Author keywords

Acetylcholine receptor; Antigenic modulation; Autoantibodies; Extracellular domains; Myasthenia gravis

Indexed keywords

AUTOANTIBODY; CHOLINERGIC RECEPTOR ANTIBODY; COMPLEMENT; IMMOBILIZED ANTIBODY; NICOTINIC RECEPTOR ALPHA; NICOTINIC RECEPTOR BETA; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

EID: 34447633501     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2007.06.014     Document Type: Article
Times cited : (18)

References (30)
  • 1
    • 0028951314 scopus 로고
    • Myasthenia gravis, a model of organ-specific autoimmune disease
    • Berrih-Aknin S. Myasthenia gravis, a model of organ-specific autoimmune disease. J. Autoimmun. 8 (1995) 139-143
    • (1995) J. Autoimmun. , vol.8 , pp. 139-143
    • Berrih-Aknin, S.1
  • 2
    • 0029874077 scopus 로고    scopus 로고
    • Stable functional expression of the adult subtype of human muscle acetylcholine receptor following transfection of the human rhabdomyosarcoma cell line TE671 with cDNA encoding the epsilon subunit
    • Beeson D., Amar M., Bermudez I., Vincent A., and Newsom-Davis J. Stable functional expression of the adult subtype of human muscle acetylcholine receptor following transfection of the human rhabdomyosarcoma cell line TE671 with cDNA encoding the epsilon subunit. Neurosci. Lett. 207 (1996) 57-60
    • (1996) Neurosci. Lett. , vol.207 , pp. 57-60
    • Beeson, D.1    Amar, M.2    Bermudez, I.3    Vincent, A.4    Newsom-Davis, J.5
  • 3
    • 0024315565 scopus 로고
    • Viability measurements in mammalian cell systems
    • Cook J.A., and Mitchell J.B. Viability measurements in mammalian cell systems. Anal. Biochem. 179 (1989) 1-7
    • (1989) Anal. Biochem. , vol.179 , pp. 1-7
    • Cook, J.A.1    Mitchell, J.B.2
  • 4
    • 0037110423 scopus 로고    scopus 로고
    • The role of antibodies in myasthenia gravis
    • De Baets M., and Stassen M.H. The role of antibodies in myasthenia gravis. J. Neurol. Sci. 202 (2002) 5-11
    • (2002) J. Neurol. Sci. , vol.202 , pp. 5-11
    • De Baets, M.1    Stassen, M.H.2
  • 5
    • 0028779203 scopus 로고
    • Myasthenia gravis
    • Drachman D.B. Myasthenia gravis. N. Engl. J. Med. 330 (1994) 1797-1810
    • (1994) N. Engl. J. Med. , vol.330 , pp. 1797-1810
    • Drachman, D.B.1
  • 7
    • 34548510504 scopus 로고    scopus 로고
    • Recent advances in the understanding and therapy of myasthenia gravis
    • Fostieri E., Kostelidou K., Poulas K., and Tzartos S. Recent advances in the understanding and therapy of myasthenia gravis. Future Neurol. 1 (2006) 799-817
    • (2006) Future Neurol. , vol.1 , pp. 799-817
    • Fostieri, E.1    Kostelidou, K.2    Poulas, K.3    Tzartos, S.4
  • 8
    • 0032128319 scopus 로고    scopus 로고
    • Regulation of acetylcholine receptor gene expression in human myasthenia gravis muscles. Evidence for a compensatory mechanism triggered by receptor loss
    • Guyon T., Wakkach A., Poea S., Mouly V., Klingel-Schmitt I., Levasseur P., Beeson D., Asher O., Tzartos S., and Berrih-Aknin S. Regulation of acetylcholine receptor gene expression in human myasthenia gravis muscles. Evidence for a compensatory mechanism triggered by receptor loss. J. Clin. Invest. 102 (1998) 249-263
    • (1998) J. Clin. Invest. , vol.102 , pp. 249-263
    • Guyon, T.1    Wakkach, A.2    Poea, S.3    Mouly, V.4    Klingel-Schmitt, I.5    Levasseur, P.6    Beeson, D.7    Asher, O.8    Tzartos, S.9    Berrih-Aknin, S.10
  • 9
    • 0023741027 scopus 로고
    • Epitopes on human acetylcholine receptor defined by monoclonal antibodies and myasthenia gravis sera
    • Heidenreich F., Vincent A., Roberts A., and Newson-Davis J. Epitopes on human acetylcholine receptor defined by monoclonal antibodies and myasthenia gravis sera. Autoimmunity 1 (1988) 285-297
    • (1988) Autoimmunity , vol.1 , pp. 285-297
    • Heidenreich, F.1    Vincent, A.2    Roberts, A.3    Newson-Davis, J.4
  • 10
    • 0035105784 scopus 로고    scopus 로고
    • Autoantibodies to the receptor tyrosine kinase MuSK in patients with myasthenia gravis without acetylcholine receptor antibodies
    • Hoch W., Mc Conville J., and Helms S. Autoantibodies to the receptor tyrosine kinase MuSK in patients with myasthenia gravis without acetylcholine receptor antibodies. Nat. Med. 7 (2001) 365-368
    • (2001) Nat. Med. , vol.7 , pp. 365-368
    • Hoch, W.1    Mc Conville, J.2    Helms, S.3
  • 11
    • 0033052980 scopus 로고    scopus 로고
    • Monoclonal antibodies raised against human acetylcholine receptor bind to all five subunits of the fetal isoform
    • Jacobson L., Beeson D., Tzartos S., and Vincent A. Monoclonal antibodies raised against human acetylcholine receptor bind to all five subunits of the fetal isoform. J. Neuroimmunol. 98 (1999) 112-120
    • (1999) J. Neuroimmunol. , vol.98 , pp. 112-120
    • Jacobson, L.1    Beeson, D.2    Tzartos, S.3    Vincent, A.4
  • 12
    • 0027182846 scopus 로고
    • Structure of nicotinic acetylcholine receptors
    • Karlin A. Structure of nicotinic acetylcholine receptors. Curr. Opin. Neurobiol. 3 (1993) 299-309
    • (1993) Curr. Opin. Neurobiol. , vol.3 , pp. 299-309
    • Karlin, A.1
  • 13
    • 33746119902 scopus 로고    scopus 로고
    • Expression and characterization of soluble forms of the extracellular domains of the beta, gamma, and epsilon subunits of the human muscle acetylcholine receptor
    • Kostelidou K., Trakas N., Zouridakis M., Bitzopoulou K., Sotiriadis A., Gavra I., and Tzartos S.J. Expression and characterization of soluble forms of the extracellular domains of the beta, gamma, and epsilon subunits of the human muscle acetylcholine receptor. FEBS J. 273 (2006) 3557-3568
    • (2006) FEBS J. , vol.273 , pp. 3557-3568
    • Kostelidou, K.1    Trakas, N.2    Zouridakis, M.3    Bitzopoulou, K.4    Sotiriadis, A.5    Gavra, I.6    Tzartos, S.J.7
  • 14
    • 0034065330 scopus 로고    scopus 로고
    • Acetylcholine receptors and myasthenia
    • Lindstrom J.M. Acetylcholine receptors and myasthenia. Muscle Nerve 23 (2000) 453-477
    • (2000) Muscle Nerve , vol.23 , pp. 453-477
    • Lindstrom, J.M.1
  • 15
    • 0019761904 scopus 로고
    • Production and assay of antibodies to acetylcholine receptors
    • Lindstrom J., Einarson B., and Tzartos S. Production and assay of antibodies to acetylcholine receptors. Methods Enzymol. 74 (1981) 432
    • (1981) Methods Enzymol. , vol.74 , pp. 432
    • Lindstrom, J.1    Einarson, B.2    Tzartos, S.3
  • 17
    • 0023860441 scopus 로고
    • Passive transfer of myasthenia gravis by immunoglobulins: lack of correlation between AChR with antibody bound, acetylcholine receptor loss and transmission defect
    • Mossman S., Vincent A., and Newsom-Davis J. Passive transfer of myasthenia gravis by immunoglobulins: lack of correlation between AChR with antibody bound, acetylcholine receptor loss and transmission defect. J. Neurol. Sci. 84 (1988) 15-28
    • (1988) J. Neurol. Sci. , vol.84 , pp. 15-28
    • Mossman, S.1    Vincent, A.2    Newsom-Davis, J.3
  • 18
    • 0017873317 scopus 로고
    • Function of circulating antibody to acetylcholine receptor in myasthenia gravis: investigation by plasma exchange
    • Newsom-Davis J., Pinching A.J., Vincent A., and Wilson S.G. Function of circulating antibody to acetylcholine receptor in myasthenia gravis: investigation by plasma exchange. Neurology 28 (1978) 266-272
    • (1978) Neurology , vol.28 , pp. 266-272
    • Newsom-Davis, J.1    Pinching, A.J.2    Vincent, A.3    Wilson, S.G.4
  • 19
    • 0037178803 scopus 로고    scopus 로고
    • Expression of soluble ligand- and antibody-binding extracellular domain of human muscle acetylcholine receptor α subunit in yeast Pichia pastoris. Role of glycosylation in α-bungarotoxin binding
    • Psaridi-Linardaki L., Mamalaki A., Remoundos M., and Tzartos S.J. Expression of soluble ligand- and antibody-binding extracellular domain of human muscle acetylcholine receptor α subunit in yeast Pichia pastoris. Role of glycosylation in α-bungarotoxin binding. J. Biol. Chem. 277 (2002) 26980-26986
    • (2002) J. Biol. Chem. , vol.277 , pp. 26980-26986
    • Psaridi-Linardaki, L.1    Mamalaki, A.2    Remoundos, M.3    Tzartos, S.J.4
  • 20
    • 12344291863 scopus 로고    scopus 로고
    • Specific immunoadsorption of the autoantibodies from myasthenic patients using the extracellular domain of the human muscle acetylcholine receptor α-subunit. Development of an antigen-specific therapeutic strategy
    • Psaridi-Linardaki L., Trakas N., Mamalaki A., and Tzartos S.J. Specific immunoadsorption of the autoantibodies from myasthenic patients using the extracellular domain of the human muscle acetylcholine receptor α-subunit. Development of an antigen-specific therapeutic strategy. J. Neuroimmunol. 159 (2005) 183-191
    • (2005) J. Neuroimmunol. , vol.159 , pp. 183-191
    • Psaridi-Linardaki, L.1    Trakas, N.2    Mamalaki, A.3    Tzartos, S.J.4
  • 21
    • 12344334808 scopus 로고    scopus 로고
    • Myasthenia gravis patients, but not healthy subjects, recognize epitopes that are unique to the epsilon-subunit of the acetylcholine receptor
    • Ragheb S., Mohamed M., and Lisak R.P. Myasthenia gravis patients, but not healthy subjects, recognize epitopes that are unique to the epsilon-subunit of the acetylcholine receptor. J. Neuroimmunol. 159 (2005) 137-145
    • (2005) J. Neuroimmunol. , vol.159 , pp. 137-145
    • Ragheb, S.1    Mohamed, M.2    Lisak, R.P.3
  • 22
    • 0016755254 scopus 로고
    • Myasthenia gravis: passive transfer from man to mouse
    • Toyka K.V., Brachman D.B., Pestronk A., and Kao I. Myasthenia gravis: passive transfer from man to mouse. Science 190 (1975) 397-399
    • (1975) Science , vol.190 , pp. 397-399
    • Toyka, K.V.1    Brachman, D.B.2    Pestronk, A.3    Kao, I.4
  • 24
    • 0345436983 scopus 로고
    • Monoclonal antibodies used to probe acetylcholine receptor structure: localization of the main immunogenic region and detection of similarities between subunits
    • Tzartos S.J., and Lindstrom J.M. Monoclonal antibodies used to probe acetylcholine receptor structure: localization of the main immunogenic region and detection of similarities between subunits. Proc. Natl. Acad. Sci. 77 (1980) 755-759
    • (1980) Proc. Natl. Acad. Sci. , vol.77 , pp. 755-759
    • Tzartos, S.J.1    Lindstrom, J.M.2
  • 25
    • 0013573650 scopus 로고
    • Specificities of antibodies to acetylcholine receptors in sera from myasthenia gravis patients measured by monoclonal antibodies
    • Tzartos S.J., Seybold M.E., and Lindstrom J.M. Specificities of antibodies to acetylcholine receptors in sera from myasthenia gravis patients measured by monoclonal antibodies. Proc. Natl. Acad. Sci. 79 (1982) 188-192
    • (1982) Proc. Natl. Acad. Sci. , vol.79 , pp. 188-192
    • Tzartos, S.J.1    Seybold, M.E.2    Lindstrom, J.M.3
  • 26
    • 0023220157 scopus 로고
    • Passive transfer of experimental autoimmune myasthenia gravis by monoclonal antibodies to the main immunogenic region of the acetylcholine receptor
    • Tzartos S., Hochschwender S., Vasquez P., and Lindstrom J. Passive transfer of experimental autoimmune myasthenia gravis by monoclonal antibodies to the main immunogenic region of the acetylcholine receptor. J. Neuroimmunol. 15 (1987) 185-194
    • (1987) J. Neuroimmunol. , vol.15 , pp. 185-194
    • Tzartos, S.1    Hochschwender, S.2    Vasquez, P.3    Lindstrom, J.4
  • 28
  • 29
    • 0043013332 scopus 로고    scopus 로고
    • Seronegative generalized myasthenia gravis: clinical features, antibodies, and their targets
    • Vincent A., Bowen J., Newsom-Davis J., and McConville J. Seronegative generalized myasthenia gravis: clinical features, antibodies, and their targets. Lancet Neurol. 2 (2003) 99-106
    • (2003) Lancet Neurol. , vol.2 , pp. 99-106
    • Vincent, A.1    Bowen, J.2    Newsom-Davis, J.3    McConville, J.4
  • 30
    • 0031923077 scopus 로고    scopus 로고
    • T-cell recognition of muscle acetylcholine receptor subunits in generalized and ocular myasthenia gravis
    • Wang Z.Y., Okita D.K., Howard Jr. J., and Conti-Fine B.M. T-cell recognition of muscle acetylcholine receptor subunits in generalized and ocular myasthenia gravis. Neurology 50 (1998) 1045-1054
    • (1998) Neurology , vol.50 , pp. 1045-1054
    • Wang, Z.Y.1    Okita, D.K.2    Howard Jr., J.3    Conti-Fine, B.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.