The effect of streptozotocin-induced diabetes on the rat seminal vesicle: A possible pathophysiological basis for disorders of ejaculation

Annals of the New York Academy of Sciences

Volumn 1084, Issue , 2006, Pages 267-279

  Morrison, John F B ^a   Dhanasekaran, S ^a   Sheen, Rajan ^a   Frampton, C M ^b   Mensah Brown, Eric ^a  

^a UNITED ARAB EMIRATES UNIVERSITY   (United Arab Emirates)

^b UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

Catecholamines; Male reproductive dysfunction; Noradrenaline; Seminal vesicle

Indexed keywords

5 HYDROXYINDOLEACETIC ACID; ADRENALIN; CALCIUM; DOPAMINE; GLUCOSE; NEUROTRANSMITTER; NORADRENALIN; POTASSIUM; SEROTONIN; STREPTOZOCIN; TRITIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CONFERENCE PAPER; CONTROLLED STUDY; EJACULATION DISORDER; ELECTROSTIMULATION; HYPERGLYCEMIA; MALE; NEUROTRANSMITTER RELEASE; NEUROTRANSMITTER UPTAKE; NONHUMAN; PATHOPHYSIOLOGY; RAT; SEMINAL VESICLE; STATISTICAL SIGNIFICANCE; STREPTOZOCIN DIABETES; SYMPATHETIC INNERVATION; SYMPATHETIC NERVE; WISTAR RAT; ANIMAL; ARTICLE; BLOOD; EJACULATION; EXPERIMENTAL DIABETES MELLITUS; GLUCOSE BLOOD LEVEL; IMPOTENCE; METABOLISM; PHYSIOLOGY;

RATTUS;

ANIMALS; BLOOD GLUCOSE; DIABETES MELLITUS, EXPERIMENTAL; DOPAMINE; EJACULATION; HYPERGLYCEMIA; IMPOTENCE; MALE; NOREPINEPHRINE; RATS; RATS, WISTAR; SEMINAL VESICLES;

EID: 34447630991     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1196/annals.1372.013     Document Type: Conference Paper

References (30)

1. EL SAKKA, A.I. 2003. Premature ejaculation in non-insulin-dependent diabetic patients. Int. J. Androl. 26: 329-334.
2. DUNSMUIR, W.D. & S.A. HOLMES. 1996. The aetiology and management of erectile, ejaculatory, and fertility problems in men with diabetes mellitus. Diabet. Med. 13: 700-708.
3. IBRAGIMOV, A.Z., T.A. ALIEV, K.I. ABDULLAEV & V.A. MIRZA-ZADE. 1990. The function of the closure apparatus of the bladder in retrograde ejaculation in diabetics. Urol. Nefrol. (Mosk.) 3: 65-68.
4. GOSLING, J.A. 1986. The distribution of noradrenergic nerves in the human lower urinary tract. Clin. Sci. (Lond.) 70 (Suppl 14): 3s-6s.
5. DANUSER, H., J.P. SPRINGER, M.A. KATOFIASC & K.B. THOR. 1997. Extrinsic innervation of the cat prostate gland: a combined tracing and immunohistochemical study J. Urol. 157: 1018-1024.
6. PAUL, A. & F. HABIB. 1998. Low-affinity nerve growth factor receptors (p75LNGFR) in human prostate tissue: stromal localisation. Urol. Res. 26: 111-116.
7. MACGROGAN, D., G. DESPRES, R. ROMAND & E. DICOU. 1991. Expression of the beta-nerve growth factor gene in male sex organs of the mouse, rat, and guinea pig. J. Neurosci. Res. 28: 567-573.
8. HELLWEG, R. & H.D. HARTUNG.1990. Endogenous levels of nerve growth factor (NGF) are altered in experimental diabetes mellitus: a possible role for NGF in the pathogenesis of diabetic neuropathy. J. Neurosci. Res. 26: 258-267.
9. MORRISON, J.F., S. DHANASEKARAN & R. SHEEN. 2004. Effects of age and streptozotocin-induced diabetes on biogenic amines in rat tail artery. Mol. Cell. Biochem. 261: 77-82.
10. MORRISON, J., F. HOWARTH & R. SHEEN. 2001. Catecholamines in the heart and adrenal gland of streptozotocin-treated (STZ) diabetic rats. Arch. Physiol. Biochem. 109: 206-208.
11. SCHMIDT, R.E., S.B. PLURAD, C.A. PARVIN & K.A. ROTH. 1993. Effect of diabetes and aging on human sympathetic autonomic ganglia. Am. J. Pathol. 143: 143-153.
12. SCHROER, J.A., S.B. PLURAD & R.E. SCHMIDT. 1992. Fine structure of presynaptic axonal terminals in sympathetic autonomic ganglia of aging and diabetic human subjects. Synapse 12: 1-13.
13. SCHMIDT, R.E. 2002. Neuropathology and pathogenesis of diabetic autonomic neuropathy. Int. Rev. Neurobiol. 50: 257-292.
14. TOMLINSON, D.R. & A.P. YUSOF. 1983. Autonomic neuropathy in the alloxan-diabetic rat. J. Auton. Pharmacol. 3: 257-263.
15. BRITLAND, S.T., R.J. YOUNG, A.K. SHARMA & B.F. CLARKE. 1992. Acute and remitting painful diabetic polyneuropathy: a comparison of peripheral nerve fibre pathology Pain 48: 361-370.
16. BEGGS, J., P.C. JOHNSON, A. OLAFSEN & C.J. WATKINS. 1992. Innervation of the vasa nervorum: changes in human diabetics. J. Neuropathol. Exp. Neurol. 51: 612-629.
17. LANGE, W. & J. UNGER. 1990. Peptidergic innervation within the prostate gland and seminal vesicle. Urol. Res. 18: 337-340.
18. AUMULLER, G. & A. RIVA. 1992. Morphology and functions of the human seminal vesicle. Andrologia 24: 183-196.
19. MENSAH-BROWN E., A. ADEM, J.M. CONLON & J.F.B. MORRISON. 2005. Changes in neuropeptide Y (NPY) - nerves and in NPY binding in the seminal vesicles and prostate gland of the streptozotocin diabetic rat. Emirates Med. J. 23: 221-227.
20. ZACHARKO, A., M.B. ARCISZEWSKI & K. WASOWICZ. 2004. Origin of the primary efferent neurons projecting to the prostate of the dog. Ann. Anat. 186: 349-356.
21. KALECZYC, J., J.P. TIMMERMANS, M. MAJEWSKI, et al. 1995. Distribution and immunohistochemical characteristics of neurons in the porcine caudal mesenteric ganglion projecting to the vas deferens and seminal vesicle. Cell Tissue Res. 282: 59-68.
22. OHKAWA, H. 1981. Evidence for adrenergic transmission in the circular smooth muscle of the guinea-pig seminal vesicle. Tohoku. J. Exp. Med. 134: 141-158.
23. KUBOTA, Y., H. HASHITANI, H. FUKUTA, et al. 2003. Mechanisms of excitatory transmission in circular smooth muscles of the guinea pig seminal vesicle. J. Urol. 169: 390-395.
24. SJOSTRAND, N.O. & M. HAMMARSTROM. 1995. Sympathetic regulation of fructose secretion in the seminal vesicle of the guinea-pig. Acta Physiol. Scand. 153: 189-202.
25. (2+)-dependent enhancement of [3H]noradrenaline uptake in PC12 cells through calmodulin-dependent kinases. Brain Res. 809: 155-164.
26. CASTELLI, M., T. ROSSI, G. BAGGIO, et al. 1985. Characterization of the contractile activity of dopamine on the rat isolated seminal vesicle. Pharmacol. Res. Commun. 17: 351-359.
27. DONG, Q., R.M. LAZARUS, L.S. WONG, et al. 1991. Pulsatile LH secretion in streptozotocin-induced diabetes in the rat. J. Endocrinol. 131: 49-55.
28. KEAST, J.R. & R.J. SAUNDERS. 1998. Testosterone has potent, selective effects on the morphology of pelvic autonomic neurons which control the bladder, lower bowel and internal reproductive organs of the male rat. Neuroscience 85: 543-556.
29. KEPPER, M. & J. KEAST. 1995. Immunohistochemical properties and spinal connections of pelvic autonomic neurons that innervate the rat prostate gland. Cell Tissue Res. 281: 533-542.
30. WANIGASEKARA, Y., M.E. KEPPER & J.R. KEAST. 2003. Immunohistochemical characterisation of pelvic autonomic ganglia in male mice. Cell Tissue Res. 311: 175-185.