Synthesis of ferulic ester dimers, functionalisation and biological evaluation as potential antiatherogenic and antiplasmodial agents

Bioorganic and Medicinal Chemistry

Volumn 15, Issue 18, 2007, Pages 6018-6026

  Rakotondramanana, D L A ^a   Delomenède, Mélanie ^a   Baltas, Michel ^a   Duran, Hubert ^a   Bedos Belval, Florence ^a   Rasoanaivo, Philippe ^b   Negre Salvayre, Anne ^c   Gornitzka, Heinz ^d  

^a Universite Toulouse III Paul Sabatier   (France)

^b INSTITUT MALGACHE DE RECHERCHES APPLIQUÉES   (Madagascar)

^c INSERM   (France)

^d Université Paul Sabatier   (France)

Author keywords

Antiatherogenic; Antioxidants; Antiplasmodial; Dihydrobenzofuran; Ferulic acid dimers

Indexed keywords

ANTIMALARIAL AGENT; CAMPTOTHECIN; CHLOROQUINE; DIHYDROBENZOFURAN DERIVATIVE; FERULIC ACID; FERULIC ACID METHYL ESTER; GALLIC ACID DERIVATIVE; LOW DENSITY LIPOPROTEIN; METHYL 3 (4 HYDROXY 3 METHOXYPHENYL) 2 [2 METHOXY 4 (3 METHOXY 3 OXOPROP 1 ENYL)PHENOXY]PROP 2 ENOATE; METHYL 3 [2 (4 HYDROXY 3 METHOXYPHENYL) 3 (3,4,5 TRIHYDROXYPHENYLCARBONYLOXYMETHYL) 7 METHOXY 2,3 DIHYDRO 1 BENZOFURAN 5 YL]PROP 2 ENOATE; METHYL 3 [2 (4 HYDROXY 3 METHOXYPHENYL) 3 HYDROXYMETHYL 7 METHOXY 2,3 DIHYDRO 1 BENZOFURAN 5 YL]PROP 2 ENOATE; METHYL 3 [2 (4 HYDROXY 3 METHOXYPHENYL) 7 METHOXY 3 METHOXYCARBONYL 2,3 DIHYDRO 1 BENZOFURAN 5 YL]PROP 2 ENOATE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIMALARIAL ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; CARBON NUCLEAR MAGNETIC RESONANCE; CELL VIABILITY; CONTROLLED STUDY; DIMERIZATION; DRUG CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; ERYTHROCYTE; HUMAN; HUMAN CELL; LEUKEMIA CELL; MALARIA; NONHUMAN; PLASMODIUM FALCIPARUM; PROTON NUCLEAR MAGNETIC RESONANCE; X RAY CRYSTALLOGRAPHY;

ANIMALS; ANTIOXIDANTS; ATHEROSCLEROSIS; CELL SURVIVAL; COUMARIC ACIDS; DIMERIZATION; ENDOTHELIUM, VASCULAR; ESTERS; HUMANS; LEUKEMIA P388; LIPOPROTEINS, LDL; MICE; MOLECULAR STRUCTURE; PARASITIC SENSITIVITY TESTS; PLASMODIUM FALCIPARUM; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

EID: 34447627517     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2007.06.047     Document Type: Article

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