Antileishmanial activity, cytotoxicity and QSAR analysis of synthetic dihydrobenzofuran lignans and related benzofurans

Bioorganic and Medicinal Chemistry

Volumn 13, Issue 3, 2005, Pages 661-669

  Miert, Sabine Van ^a   Dyck, Stefaan Van ^a   Schmidt, Thomas J ^b   Brun, Reto ^c   Vlietinck, Arnold ^a   Lemière, Guy ^a   Pieters, Luc ^a  

^a UNIVERSITY OF ANTWERP   (Belgium)

^b HEINRICH HEINE UNIVERSITY   (Germany)

^c SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE   (Switzerland)

Author keywords

Cytotoxicity; Dihydrobenzofuran lignans; Leishmania; QSAR

Indexed keywords

ANTILEISHMANIAL AGENT; ANTINEOPLASTIC AGENT; BENZOFURAN DERIVATIVE; CAFFEIC ACID; CHLOROQUINE; DIHYDROBENZOFURAN DERIVATIVE; ESTER DERIVATIVE; LIGNAN DERIVATIVE;

ANTIPROTOZOAL ACTIVITY; ARTICLE; CELL ASSAY; CONTROLLED STUDY; CYTOTOXICITY TEST; DRUG SYNTHESIS; HUMAN; HUMAN CELL; LEISHMANIA DONOVANI; MACROPHAGE; MOLECULAR MODEL; NONHUMAN; PLASMODIUM FALCIPARUM; QUANTITATIVE STRUCTURE ACTIVITY RELATION; TRYPANOSOMA CRUZI; TRYPANOSOMA RHODESIENSE; TUMOR CELL LINE;

ANIMALS; ANTIPROTOZOAL AGENTS; BENZOFURANS; CELL LINE, TUMOR; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; LEISHMANIA; LIGNANS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;

PLASMODIUM FALCIPARUM; TRYPANOSOMA; TRYPANOSOMA BRUCEI RHODESIENSE; TRYPANOSOMA CRUZI;

EID: 11844287538     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2004.10.058     Document Type: Article

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