Potent and specific action of the mGlu1 antagonists YM-298198 and JNJ16259685 on synaptic transmission in rat cerebellar slices

British Journal of Pharmacology

Volumn 151, Issue 6, 2007, Pages 870-876

  Fukunaga, I ^a   Yeo, C H ^a   Batchelor, A M ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Cerebellum; Metabotropic glutamate receptors; Purkinje cell

Indexed keywords

3,4 DIHYDRO 2H PYRANO[2,3 B]QUINOLIN 7 YL 4 METHOXYCYCLOHEXYLMETHANONE; 6 AMINO N CYCLOHEXYL N,3 DIMETHYLTHIAZOLO[3,2 A]BENZIMIDAZOLE 2 CARBOXAMIDE; JNJ 16259685; METABOTROPIC RECEPTOR 1; METABOTROPIC RECEPTOR ANTAGONIST; UNCLASSIFIED DRUG; YM 298198;

ANIMAL EXPERIMENT; ARTICLE; BRAIN SLICE; CEREBELLUM; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFICACY; DRUG POTENCY; DRUG SPECIFICITY; EXCITATORY POSTSYNAPTIC POTENTIAL; IC 50; INHIBITION KINETICS; LIPOPHILICITY; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; PURKINJE CELL; RAT; SENSITIVITY AND SPECIFICITY; SYNAPTIC TRANSMISSION;

ANIMALS; BENZIMIDAZOLES; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHYSIOLOGY; EXCITATORY POSTSYNAPTIC POTENTIALS; HYDROPHOBICITY; INHIBITORY CONCENTRATION 50; PURKINJE CELLS; QUINOLINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, AMPA; RECEPTORS, METABOTROPIC GLUTAMATE; SYNAPTIC TRANSMISSION; THIAZOLES;

EID: 34447562706     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0707286     Document Type: Article

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