Montelukast as add-on therapy to β-agonists and late airway response

European Respiratory Journal

Volumn 30, Issue 1, 2007, Pages 56-61

  Rosewich, Martin ^a   Rose, M A ^a   Eickmeier, O ^a   Travaci, M ^a   Kitz, R ^a   Zielen, S ^a  

^a GOETHE UNIVERSITY   (Germany)

Author keywords

Asthma; Bronchial allergen challenge; Early asthmatic response; Exhaled nitric oxide fraction; Late asthmatic response; Montelukast

Indexed keywords

HOUSE DUST ALLERGEN; MONTELUKAST; NITRIC OXIDE; PLACEBO; SALBUTAMOL;

ADD ON THERAPY; ADULT; AIRWAY CONDUCTANCE; ALLERGIC ASTHMA; ALLERGIC REACTION; ALLERGY TEST; ARTICLE; BRONCHODILATATION; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; EXPIRED AIR; FEMALE; FORCED EXPIRATORY VOLUME; HOUSE DUST ALLERGY; HUMAN; MALE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SINGLE DRUG DOSE;

ACETATES; ADMINISTRATION, ORAL; ADRENERGIC BETA-AGONISTS; ADULT; ANTI-ASTHMATIC AGENTS; ASTHMA; BRONCHI; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; FEMALE; HUMANS; LEUKOTRIENE ANTAGONISTS; MALE; PLACEBOS; QUINOLINES; TIME FACTORS;

EID: 34447553396     PISSN: 09031936     EISSN: None     Source Type: Journal    
DOI: 10.1183/09031936.00063106     Document Type: Article

References (34)

1. Jatakanon A, Lim S, Kharitonov SA, Chung KF, Barnes PJ. Correlation between exhaled nitric oxide, sputum eosinophils, and methacholine responsiveness in patients with mild asthma. Thorax 1998; 53: 91-95.
2. Jatakanon A, Lim S, Chung KF, Barnes PJ. An inhaled steroid improves markers of airway inflammation in patients with mild asthma. Eur Respir J 1998; 12: 1084-1088.
3. Kharitonov SA, Yates D, Robbins RA, Logan-Sinclair R, Shinebourne EA, Barnes PJ. Increased nitric oxide in exhaled air of asthmatic patients. Lancet 1994; 343: 133-135.
4. Befus D. The role of the mast cell in allergic bronchospasm. Can J Physiol Pharmacol 1987; 65: 435-441.
5. Cockcroft DW. Mechanism of perennial allergic asthma. Lancet 1983; 2: 253-256.
6. Sears MR. Asthma treatment: inhaled beta-agonists. Can Respir J 1998; 5: Suppl. A, 54A-59A.
7. Robertson DG, Kerigan AT, Hargreave FE, Dolovich J. Late asthmatic responses induced by ragweed pollen allergen. J Allergy Clin Immunol 1974; 54: 244-254.
8. Pelikan Z, Pelikan-Filipek M. The late asthmatic response to allergen challenge - Part I. Ann Allergy 1986; 56: 414-420.
9. Pelikan Z, Pelikan-Filipek M. The late asthmatic response to allergen challenge - Part II. Ann Allergy 1986; 56: 421-435.
10. Dolovich J, Hargreave FE, Jordana M, Denburg J. Late-phase airway reaction and inflammation. J Allergy Clin Immunol 1989; 83: 521-524.
11. Henderson WR Jr. Role of leukotrienes in asthma. Ann Allergy 1994; 72: 272-278.
12. Perry TT, Corren J, Philip G, et al. Protective effect of montelukast on lower and upper respiratory tract responses to short-term cat allergen exposure. Ann Allergy Asthma Immunol 2004; 93: 431-438.
13. 2-agonists, leukotriene receptor antagonists, and a 5-lipoxygenase inhibitor on exercise-induced asthma. J Allergy Clin Immunol 2000; 106: 500-506.
14. Dahlen SE, Malmstrom K, Nizankowska E, et al. Improvement of aspirin-intolerant asthma by montelukast, a leukotriene antagonist: a randomised, double-blind, placebo-controlled trial. Am J Respir Crit Care Med 2002; 165: 9-14.
15. Leff JA, Busse WW, Pearlman D, et al. Montelukast, a leukotriene-receptor antagonist, for the treatment of mild asthma and exercise-induced bronchoconstriction. N Engl J Med 1998; 339: 147-152.
16. Diamant Z, Grootendorst DC, Veselic-Charvat M, et al. The effect of montelukast (MK-0476), a cysteinyl leukotriene receptor antagonist, on allergen-induced airway responses and sputum cell counts in asthma. Clin Exp Allergy 1999; 29: 42-51.
17. Phipatanakul W, Nowak-Wegrzyn A, Eggleston PA, et al. The efficacy of montelukast in the treatment of cat allergen-induced asthma in children. J Allergy Clin Immunol 2002; 109: 794-799.
18. Cylly A, Kara A, Ozdemir T, Ogus C, Gulkesen KH. Effects of oral montelukast on airway function in acute asthma. Respir Med 2003; 97: 533-536.
19. Dockhorn RJ, Baumgartner RA, Leff JA, et al. Comparison of the effects of intravenous and oral montelukast on airway function: a double blind, placebo controlled, three period, crossover study in asthmatic patients. Thorax 2000; 55: 260-265.
20. Recommendations for standardized procedures for the online and off-line measurement of exhaled lower nitric oxide and nasal nitric oxide in adults and children - 1999. The official statement of the American Thoracic Society was adopted by the ATS Board of Directors, July 1999. Am J Respir Crit Care Med 1999; 160: 2104-2117.
21. Wonne R, Hofmann D, Posselt HG, Stover B, Bender SW. Bronchial allergy in cystic fibrosis. Clin Allergy 1985; 15: 455-463.
22. O'Driscoll BR, Kay AB. Leukotrienes and lung disease. Thorax 1982; 37: 241-245.
23. De Sanctis GT, MacLean JA, Hamada K, et al. Contribution of nitric oxide synthases 1, 2, and 3 to airway hyperresponsiveness and inflammation in a murine model of asthma. J Exp Med 1999; 189: 1621-1630.
24. 4: potentiation of inflammation. Am J Respir Cell Mol Biol 2000; 23: 572-577.
25. Walch L, Norel X, Gascard JP, Brink C. Functional studies of leukotriene receptors in vascular tissues. Am J Respir Crit Care Med 2000; 161: S107-S111.
26. Palmqvist M, Bruce C, Sjostrand M, Arvidsson P, Lotvall J. Differential effects of fluticasone and montelukast on allergen-induced asthma. Allergy 2005; 60: 65-70.
27. Leigh R, Vethanayagam D, Yoshida M, et al. Effects of montelukast and budesonide on airway responses and airway inflammation in asthma. Am J Respir Crit Care Med 2002; 166: 1212-1217.
28. Paggiaro PL, Dente FL, Morelli MC, et al. Postallergen induced budesonide reduces late asthmatic response and inhibits the associated increase of airway responsiveness to methacholine in asthmatics. Am J Respir Crit Care Med 1994; 149: 1447-1451.
29. Kharitonov SA, O'Connor BJ, Evans DJ, Barnes PJ. Allergen-induced late asthmatic reactions are associated with elevation of exhaled nitric oxide. Am J Respir Crit Care Med 1995; 151: 1894-1899.
30. Szefler SJ, Phillips BR, Martinez FD, et al. Characterization of within-subject responses to fluticasone and montelukast in childhood asthma. J Allergy Clin Immunol 2005; 115: 233-242.
31. Singh SD, Allen DJ. Intravenous montelukast. Thorax 2000; 55: 1070.
32. Camargo CA Jr, Smithline HA, Malice MP, Green SA, Reiss TF. A randomized controlled trial of intravenous montelukast in acute asthma. Am J Respir Crit Care Med 2003; 167: 528-533.
33. Melo RE, Sole D, Naspitz CK. Exercise-induced bronchoconstriction in children: montelukast attenuates the immediate-phase and late-phase responses. J Allergy Clin Immunol 2003; 111: 301-307.
34. Norris V, Choong L, Tran D, et al. Effect of IVL745, a VLA-4 antagonist, on allergen-induced bronchoconstriction in patients with asthma. J Allergy Clin Immunol 2005; 116: 761-767.