Antiviral effects of quinine sulfate on HSV-1 HaCat cells infected: Analysis of the molecular mechanisms involved

Journal of Dermatological Science

Volumn 47, Issue 3, 2007, Pages 253-255

  Baroni, A ^a   Paoletti, I ^b   Ruocco, E ^a   Ayala, F ^b   Corrado, F ^b   Wolf, R ^c   Tufano, M A ^b   Donnarumma, G ^b  

^a SECOND UNIVERSITY OF NAPLES   (Italy)

^b Faculty of Medicine and Surgery   (Italy)

^c KAPLAN MEDICAL CENTER   (Israel)

Author keywords

HaCat; Hsp70; HSV 1; Quinine sulfate

Indexed keywords

HEAT SHOCK PROTEIN 70; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN VP16; QUININE SULFATE;

ANTIVIRAL ACTIVITY; DRUG MECHANISM; ENZYME LINKED IMMUNOSORBENT ASSAY; HERPES SIMPLEX VIRUS 1; HUMAN; LETTER; MONOLAYER CULTURE; PRIORITY JOURNAL; VERO CELL; VIRUS PLAQUE; VIRUS REPLICATION; VIRUS RESISTANCE; VIRUS STRAIN; WESTERN BLOTTING;

ANIMALS; ANTIMALARIALS; ANTIVIRAL AGENTS; CELL LINE, TUMOR; CERCOPITHECUS AETHIOPS; HERPES SIMPLEX VIRUS PROTEIN VMW65; HERPESVIRUS 1, HUMAN; HSP70 HEAT-SHOCK PROTEINS; HUMANS; IMMEDIATE-EARLY PROTEINS; NF-KAPPA B; QUININE; VERO CELLS; VIRUS REPLICATION;

EID: 34447529044     PISSN: 09231811     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jdermsci.2007.05.009     Document Type: Letter

References (10)

1. Wolf R., Wolf D., and Ruocco V. Antimalarials: unapproved uses or indications. Clin Dermatol 18 (2000) 17-35
2. Paton N.I., and Aboulhab J. Hydroxychloroquine, hydroxyurea and didanosine as initial therapy for HIV-infected patients with low viral load: safety, efficacy and resistance profile after 144 weeks. HIV Med. 6 1 (2005) 13-20
3. Shlesinger M.J. Heat shock proteins. J Biol Chem 265 (1990) 12111-12114
4. 1: a translational block associated with HSP70 synthesis. J Virol 68 (1994) 6890-6899
5. Barnes P.J., and Karin M. Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases. N Engl J Med 336 (1997) 1066-1071
6. Amici C., Rossi A., Costanzo A., Cifre S., Marinari B., Balsamo M., et al. Herpes simplex virus disrupts NF-{kappa}B regulation by blocking its recruitment on the I{kappa}B{alpha} promoter and directing the factor on viral genes. J Biol Chem 281 11 (2006) 7110-7117
7. Gregory D., Hagett D., Holmes D., Money E., and Bachenheimer S.L. Efficient replication by herpes simplex virus type 1 involves activation of the IkappaB kinase-IkappaB-p65 pathway. J Virol 78 (2004) 13582-13590
8. Wolf R., Baroni A., Greco R., Corrado F., Ruocco E., Tufano M.A., et al. Quinine sulfate and HSV replication. Dermatol Online J 9 3 (2003) 3
9. Andrews N.C., and Faller D.V. A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells. Nucleic Acids Res 19 (1991) 2499-2506
10. Baroni A., Paoletti I., Greco R., Satriano R.A., Ruocco E., Tufano M.A., et al. Immunomodulatory effects of a set of amygdalin analogues on human keratinocytes cells. Exp Dermatol 14 11 (2005) 854-859