Deltamethrin induces mitochondrial membrane permeability and altered expression of cytochrome C in rat brain

Journal of Applied Toxicology

Volumn 27, Issue 4, 2007, Pages 368-372

  Chen, Dan ^a   Huang, Xiaowei ^a   Liu, Linlin ^a   Shi, Nian ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Cytochrome C; Membrane potential; Mitochondria; Permeability transition

Indexed keywords

CYTOCHROME C; CYTOCHROME C OXIDASE; DELTAMETHRIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; ENZYME ACTIVITY; HIPPOCAMPUS; MEMBRANE PERMEABILITY; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; NERVE CELL; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPRAGUE DAWLEY RAT;

ANALYSIS OF VARIANCE; ANIMALS; BLOTTING, WESTERN; BRAIN; CEREBRAL CORTEX; CYTOCHROMES C; ELECTRON TRANSPORT COMPLEX IV; HIPPOCAMPUS; INJECTIONS, INTRAPERITONEAL; INSECTICIDES; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MITOCHONDRIAL MEMBRANES; NITRILES; PERMEABILITY; PYRETHRINS; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS;

RATTUS;

EID: 34447520016     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.1215     Document Type: Article

References (33)

1. Abalis IM, Eldefrawi EM, Eldefrawi AT. 1986. Effects of insecticide on GABA-induced chloride flux into rat brain microsacs. J. Toxicol. Environ. Health 18: 13-23.
2. Andreyev AY, Fahy B, Fiskum G. 1998. Cytochrome c release from brain mitochondria is independent of the mitochondrial permeability transition. FEBS Lett. 439: 373-376.
3. Araragi S, Kondoh M, Kawase M, Saito S. 2003. Mercuric chloride induces apoptosis via a mitochondrial-dependent pathway in human leukemia cells. Toxicology 184: 1-9.
4. Berman SB, Watkins SC, Hastings TG. 2000. Quantitative biochemical and ultrastructural comparison of mitochondrial permeability transition in isolated brain and liver mitochondria: evidence for reduced sensitivity of brain mitochondria. Exp. Neurol. 164: 415-425.
5. Bernardi P. 1999. Mitochondrial transport of cations: channels, exchangers, and permeability transition. Physiol. Rev. 79: 1127-1155.
6. Bloomquist JR, Barlow RL, Gillette JS, Li W, Kirby ML. 2002. Selective effects of insecticides on nigrostriatal dopaminergic nerve pathways. Neurotoxicology 23: 537-544.
7. Bradford MM. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72: 248-254.
8. Clark JM, Matsumura F. 1982. Two different types of inhibitory effects of pyrethroids on nerve Ca and Ca-Mg-ATPase activity in the squid Loligo pealei. Pestic. Biochem. Physiol. 18: 180-190.
9. Deng XL, Cai NS, McCoy MT, Chen WG, Trush MA, Cadet JL. 2002. Methamphetamine induces apoptosis in an immortalized rat striatal cell line by activating the mitochondrial cell death pathway. Neuropharmacology 42: 837-845.
10. 2+ in dissociated brain cells. Brain Res. 499: 383-387.
11. Dodd PR, Hardy JA, Oakley AE, Edwardson JA, Perry EK, Delaunoy JP. 1981. A rapid method for preparing synaptosomes: comparison, with alternative procedures. Brain Res. 226: 107-118.
12. Green DR, Reed JC. 1998. Mitochondria and apoptosis. Sci. 281: 1309-1312.
13. Hevner RF, Liu S, Wong-Riley MTT. 1993. An optimized method for determining cytochrome oxidase activity in brain tissue homogenates. J. Neurol. Methods 50: 309-319.
14. Karen DJ, Li W, Harp PR, Gillette JS, Bloomquist JR. 2001. Striatal dopaminergic pathways as a target for the insecticides permethrin and chlorpyrifos. NeuroToxicology 22: 811-817.
15. Kirby ML, Castagnoli K, Bloomquist JR. 1999. In vivo effects of deltamethrin on dopamine neurochemistry and the role of augmented neurotransmitter release. Pestic. Biochem. Physiol. 65: 160-168.
16. Maaser K, Sutter AP, Scherubl H. 2005. Mechanisms of mitochondria apoptosis induced by peripheral benzodiazepine receptor ligands in human colorectal cells. Biochem. Biophys. Res. Commun. 332: 646-652.
17. Malatesta F, Antonini G, Sarti P, Brunori M. 1995. Structure and function of a molecular machine: cytochrome c oxidase. Biophys. Chem. 54: 1-33.
18. Marban E, Yamagishi T, Tomaselli GF. 1998. Structure and function of voltage-gated sodium channels. J. Physiol. 508: 647-657.
19. Meeusen S, McCaffery JM, Nunnari J. 2004. Mitochondrial fusion intermediates revealed in vitro. Science 305(5691): 1747-1752.
20. Morais CS, Swerdlow RH, Oliveira CR. 2002. Induction of cytochrome c-mediated apoptosis by amyloid beta 25-35 requires functional mitochondria. Brain Res. 931: 117-125.
21. Narahashi T. 1982. Cellular and molecular mechanisms of action of insecticides: neurophysiological approach. Neurobehav. Toxicol. Teratol. 4: 753-758.
22. Panov AV, Andreeva L, Greenamyre JL. 2004. Quantitative evaluation of the effects of mitochondrial permeability transition pore modifiers on accumulation of calcium phosphate: comparison of rat liver and brain mitochondria. Arch. Biochem. Biophys. 424: 44-52.
23. Ravagnan L, Roumier T, Kroemer G. 2002. Mitochondria, the killer organelles and their weapons. J. Cell. Physiol. 192: 131-137.
24. Reers M, Smith TW, Chen LB. 1991. J-aggregate formation of a carbocyanine as a quantitative fluorescent indicator of membrane potential. Biochemistry 30: 4480-4486.
25. 6(3) or rhodamine 123, is a reliable fluorescent probe to assess ΔΨ changes in intact cells: implications for studies on mitochondrial functionality during apoptosis. FEBS Lett. 411: 77-82.
26. Soderlund DM, Clark JT, Sheet LP, Mullin LS, Piccirillo VJ, Sargent D, Stevens JT, Weiner ML. 2002. Mechanisms of pyrethroid neurotoxicity: implications for cumulative risk assessment. Toxicology 171: 3-59.
27. Sullivan PG, Keller JN, Bussen WL, Scheff SW. 2002. Cytochrome c release and caspase activation after traumatic brain injury. Brain Res. 949: 88-96.
28. Tirosh O, Sen CK, Roy S, Packer L. 2000. Cellular and mitochondrial changes in glutamate-induced HT4 neuronal cell death. Neuroscience 97: 531-541.
29. Walter L, Nogueira V, Leverve X, Heitz MP, Bernardi P, Fontaine E. 2000. Three classes of ubiquinone analogs regulate the mitochondrial permeability transition pore through a common site. J. Biol. Chem. 275: 29521-29527.
30. Wu A, Hu Q, Liu Y. 2000. Deltamethrin induces altered expression of P53, Bax and Bcl-2 in rat brain. Neurosci. Lett. 284: 29-32.
31. Wu A, Liu Y. 2000. Deltamethrin induces delayed apoptosis and altered expression of p53 and bax in rat brain. Environ. Toxicol. Pharmacol. 8: 183-189.
32. Zlotkin E, Devonshire AL, Warmke JW. 1999. The pharmacological flexibility of the insect voltage gated sodium channel: toxicity of AaIT to knockdown resistant (kdr) flies. Insect Biochem. Mol. Biol. 29: 849-853.
33. Zoratti M, Szabo I. 1995. The mitochondrial permeability transition. Biochim. Biophys. Acta 1241: 139-176.