Interactions between Iron(III)-hydroxide Polymaltose Complex and Commonly Used Medications Laboratory studies in rats

Arzneimittel-Forschung/Drug Research

Volumn 57, Issue 6, 2007, Pages 370-375

  Funk, Felix ^a   Canclini, Camillo ^a   Geisser, Peter ^a  

^a Vifor (International) Inc   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ALUMINUM HYDROXIDE; AURANOFIN; BROMAZEPAM; CALCIUM ACETAT; CALCIUM ACETATE; CALCIUM CARBONATE; CALCIUM PHOSPHATE; COLECALCIFEROL; DECALCIT; ELEVIT PRONATAL; IRON POLYMALTOSE; MAGNESIUM ASPARTATE; MALTOFER; METHYLDOPA; MULTIVITAMIN; PARACETAMOL; PENICILLAMINE; SALAZOSULFAPYRIDINE; TETRACYCLINE; UNCLASSIFIED DRUG;

ANEMIA; ARTICLE; BLOOD SAMPLING; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; IRON DEFICIENCY; IRON RESTRICTION; IRON THERAPY; IRON TRANSPORT; MONOTHERAPY; NONHUMAN; PHYSICAL CHEMISTRY; RAT;

ANIMALS; BODY WEIGHT; CHELATING AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; FERRIC COMPOUNDS; HEMOGLOBINS; IRON; IRON RADIOISOTOPES; MALE; RATS;

EID: 34447340659     PISSN: 00044172     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0031-1296685     Document Type: Article

References (23)

1. Neuvonen PJ, Gothoni G, Hackman R, Björksten K. Interference of iron with the absorption of tetracyclines in man. Brit Med J. 1970; 4: 532-534.
2. Netter P, Bannwarth B, Péré P. Clinical pharmacokinetics of D-penicillamine. Clin Pharmacokin. 1987; 13: 317-333.
3. Burckhardt-Herold S, Klotz J, Funk F, Büchi R, Petrig J, Geisser P Interactions between iron(III)-hydroxide polymaltose complex and commonly used drugs. Simulations and in vitro studies. Arzneimittel-Forschung (Drug Research). 2007; 57(6a): 360-369.
4. Schneider W. Iron hydrolysis and the biochemistry of iron-The interplay of hydroxide and biogenic ligands. Chimia. 1998; 42: 9-20.
5. Geisser P, Müller A. Iron pharmacokinetics after administration of ferri-hydroxide-polymaltose complex in rats. Arzneimittel-Forschung (Drug Research). 1984; 34: 1560-1569.
6. Geisser P, Baer M, Schaub E. Structure/histotoxicity relationship of parenteral iron preparations. ArzneimittelForschung (Drug Research). 1992; 42: 1439-1452.
7. Geisser P, ed. Iron therapy with special emphasis on oxidative stress. Rorschach: Löpfe-Benz AG; 1998.
8. Bothwell TH, Charlton RW, Cook JD, Finch CA. Iron Metabolism in Man. Oxford-London: Blackwell Scientific Publica-tions; 1979.
9. Martinez-Torres C, Renzi M, Layrisse M. Iron absorption by humans from hemosiderin and ferritin, further studies. J Nutr. 1976; 106: 128-135.
10. Layrisse M, Garcia-Casal MN, Solano L, Baron MA, Arguello F, Llovera D, et al. Iron bioavailabilty in humans from breakfast enriched with iron bis-glycine chelate, phytates and polyphenols. J Nutr. 2000; 130: 2195-2199.
11. Kaltwasser JP, Werner E, Schalk KP, Glasl H. Effect of tea on food iron absorption in idiopathic haemochromatosis. In: Urushizaki I, et al, eds. Structure and Function of Iron Storage and Transport Proteins. Amsterdam: Elsevier Science; 1983. p. 519.
12. Disler PB, Lynch SR, Charlton RW, Torrance JD, Bothwell TH. The effect of tea on iron absorption. Gut. 1975; 16: 193-200.
13. Gillooly M, Bothwell TH, Charlton RW, Torrance JD, Bez-woda WR, Macphail AP, et al. Factors affecting the absorption of iron from cereals. Br J Nutr. 1984; 51: 37-46.
14. Funk F, Long GJ, Hautot D, Buchi R, Christl I, Weidler PG. Physical and chemical characterization of therapeutic iron containing materials: a study of several superparamagnetic drug formulations with the P-FeOOH or ferrihydrite structure. Hyperfine Interactions. 2001; 136: 73-95.
15. Forbes AL, Arnaud MJ, Chichester CO, Cook JD, Harrison BN, Hurrel RF et al. Comparison of in vitro, animal, and clinical determinations of iron bioavailability: International Nutritional Anemia Consultative Group Task Force Report on Iron Bioavailability. Am J Clin Nutr. 1989; 49: 225-238.
16. Geisser P In vitro studies on interactions of iron salts and complexes with food-stuffs and medicaments. Arzneimittel-Forschung (Drug Research). 1990; 40: 754-760.
17. Toblli E, Brignoli R. Iron(III)-hydroxide polymaltose complex in iron deficiency anemia. Review and meta-analysis. Arzneimittel-Forschung (DrugResearch). 2007; 57(6a): 431-438.
18. Potgieter MA, Potgieter JH, Venter C, Venter JL, Geisser P Effect of oral tetracycline on iron absorption from iron(III)-hydroxide polymaltose complex in patients with iron deficiency anemia. A single-centre randomized controlled isotope study. Arzneimittel-Forschung (Drug Research). 2007; 57(6a): 376-384.
19. Neuvonen PJ. Interaction with absorption of tetracyclines. Drugs 1976; 11: 45-54.
20. Seitz C, Gracia P, Arancibia A. Influence of ethanol ingestion on tetracyclines kinetics. Int J Clin Pharmacol Ther. 1995; 33: 462-464.
21. Neuvonen PJ, Turakka H. Inhibitory effect of various iron salts on the absorption of tetracycline in man. Eur J Clin Pharmacol. 1974; 7: 357-360.
22. Potgieter MA, Potgieter JH, Venter C, Venter JL, Geisser P. Effect of oral aluminium hydroxide on iron absorption from iron(III)-hydroxide polymaltose complex in patients with iron deficiency anemia. A single-centre randomized controlled isotope study. Arzneimittel-Forschung (Drug Research). 2007; 57(6a): 392-400.
23. Lundqvist H, Sjoberg F. Food interaction of oral uptake of iron. A clinical trial using 59Fe. Arzneimittel-Forschung (Drug Research). 2007; 57(6a): 401-416.