Differences in allele frequencies of ACE I/D polymorphism between Northern and Southern Europe at different ages

Atherosclerosis

Volumn 193, Issue 2, 2007, Pages 455-457

  Panza, Francesco ^a   Capurso, Cristiano ^b   D'Introno, Alessia ^a   Colacicco, Anna Maria ^a   Kehoe, Patrick G ^c   Seripa, Davide ^d   Pilotto, Alberto ^e   Capurso, Antonio ^a   Solfrizzi, Vincenzo ^a  

^a UNIVERSITY OF BARI   (Italy)

^b UNIVERSITY OF FOGGIA   (Italy)

^c UNIVERSITY OF BRISTOL   (United Kingdom)

^d Research Department   (Italy)

^e IRCSS   (Italy)

Author keywords

ACE I D polymorphism; Geographical trend; Myocardial infarction; Southern Italy

Indexed keywords

APOLIPOPROTEIN B; DIPEPTIDYL CARBOXYPEPTIDASE; TRIACYLGLYCEROL;

CARDIOVASCULAR RISK; CHOLESTEROL BLOOD LEVEL; CHROMOSOME 17; GENE FREQUENCY; GENE INSERTION; GENETIC POLYMORPHISM; GENOTYPE; GEOGRAPHIC DISTRIBUTION; HEART INFARCTION; HUMAN; LETTER; PRIORITY JOURNAL; SYSTOLIC BLOOD PRESSURE; TRIACYLGLYCEROL BLOOD LEVEL;

ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; EUROPE; FEMALE; GENE FREQUENCY; HUMANS; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; PEPTIDYL-DIPEPTIDASE A; POLYMORPHISM, GENETIC;

EID: 34447336682     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2006.08.040     Document Type: Letter

References (13)

1. Muthumala A., Cooper J., and Humphries SE on behalf of the HIFMECH Study Group. European differences in the association between ACE I/D polymorphism and incidence of MI may be explained by gene-lipid interaction. Atherosclerosis 189 (2006) 474-477
2. Rigat B., Alhenc-Gelas F., Hubert C., et al. An insertion deletion polymorphism in the angiotensin i-converting enzyme gene accounting for half the variance of serum enzyme levels. J Clin Invest 86 (1990) 1343-1346
3. Cambien F., Poirier O., Lecerf L., et al. Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction. Nature 359 (1992) 641-644
4. Kehoe P.G., Russ C., McIlroy S., et al. Variation in DCP1, encoding ACE, is associated with susceptibility to Alzheimer disease. Nat Genet 21 (1999) 71-72
5. Schachter F., Faure-Delanef L., Guenot F., et al. Genetic associations with human longevity at the APOE and ACE loci. Nat Genet 6 (1994) 29-32
6. Butler R., Morris A.D., and Struthers A.D. Angiotensin-converting enzyme gene polymorphism and cardiovascular disease. Clin Sci 93 (1997) 391-400
7. Panza F., Solfrizzi V., D'Introno A., et al. Shifts in angiotensin I converting enzyme insertion allele frequency across Europe: implications for Alzheimer's disease risk. J Neurol Neurosurg Psychiatry 74 (2003) 1159-1161
8. Panza F., Solfrizzi V., Torres F., et al. Decreased frequency of apolipoprotein E ε4 allele from Northern to Southern Europe in Alzheimer's disease patients and centenarians. Neurosci Lett 277 (1999) 53-56
9. Panza F., Solfrizzi V., Torres F., et al. Apolipoprotein E in Southern Italy: protective effect of epsilon 2 allele in early- and late-onset sporadic Alzheimer's disease. Neurosci Lett 292 (2000) 79-82
10. Panza F., D'Introno A., Colacicco A.M., et al. Vascular risk and genetics of sporadic late-onset Alzheimer's disease. J Neural Transm 111 (2004) 69-89
11. Panza F., Solfrizzi V., D'Introno A., et al. Angiotensin I converting enzyme (ACE) gene polymorphism in centenarians: different allele frequencies between the North and South of Europe. Exp Gerontol 38 (2003) 1015-1020
12. Seripa D., Franceschi M., Matera M.G., et al. Sex differences in the association of apolipoprotein E and angiotensin-converting enzyme gene polymorphisms with healthy aging and longevity: a population-based study from Southern Italy. J Gerontol 61 (2006) 918-923
13. Lehmann D.J., Cortina-Borja M., Warden D.R., et al. Large meta-analysis establishes the ACE insertion-deletion polymorphism as a marker of Alzheimer's disease. Am J Epidemiol 162 (2005) 305-317