Bax expression and apoptotic cell death in Fanconi anaemia peripheral blood lymphocytes

Cell Proliferation

Volumn 40, Issue 4, 2007, Pages 558-567

  Baruque, G A ^b   Bitencourt, M A ^c   Pasquini, R ^c   Castelo Branco, M T L ^b   Llerena Jr , J C ^b,d   Rumjanek, V M ^a,b  

^a Instituto de Bioquímica Médica   (Brazil)

^b FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^c FEDERAL UNIVERSITY OF PARANÁ   (Brazil)

^d INSTITUTO OSWALDO CRUZ   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN BAX; PROTEIN BCL 2;

ADOLESCENT; ADULT; APOPTOSIS; ARTICLE; CELL DEATH; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE PREDISPOSITION; FANCONI ANEMIA; HUMAN; HUMAN CELL; PERIPHERAL BLOOD MONONUCLEAR CELL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS;

EID: 34447324144     PISSN: 09607722     EISSN: 13652184     Source Type: Journal    
DOI: 10.1111/j.1365-2184.2007.00446.x     Document Type: Article

References (17)

1. Auerbach AD, Rogatko A, Schroeder-Kurth TM (1989) International Fanconi anemia registry: relation of clinical symptoms to diepoxy-butane sensitivity. Blood 73, 391 396.
2. Baruque GA, Bitencourt MA, Pasquini R, Castelo-Branco MTL, Llerena JC, Rumjanek VM (2005) Apoptosis and expression of anti- and pro-apoptotic proteins in peripheral blood mononuclear cells of Fanconi anaemia patients: a study of 73 cases. Eur. J. Haematol. 75, 384 390.
3. Cumming RC, Liu JM, Youssoufian H, Buchwald M (1996) Suppression of apoptosis in hematopoietic factor-dependent progenitor cell lines by expression of the FAC gene. Blood 88, 4558 4567.
4. D'Andrea AD, Grompe M (1997) Molecular biology of Fanconi anemia: implications for diagnosis and therapy. Blood 90, 1725 1736.
5. Fagerlie S, Bagby GC (2006) Immune defects in Fanconi anemia. Crit. Rev. Immunol. 26, 81 96.
6. Fagerlie S, Lensch MW, Pang Q, Bagby GC Jr. (2001) The Fanconi anemia group C gene product: signaling functions in hematopoietic cells. Exp. Hematol. 29, 1371 1381.
7. Ferrer M, Izeboud T, Ferreira CG, Span SW, Giaccone G, Kruyt FAE (2003) Cisplatin triggers apoptotic or nonapoptotic cell death in Fanconi anemia lymphoblasts in a concentration-dependent manner. Exp. Cell Res. 286, 381 395.
8. Green DR, Reed JC (1998) Mitochondria and apoptosis. Science 281, 1309 1312.
9. Ishida R, Buchwald M (1982) Susceptibility of Fanconi's anemia lymphoblasts to DNA-cross-linking and alkylating agents. Cancer Res. 42, 4000 4006.
10. Kruyt FAE, Dijikmans LM, van den Berg TK, Joenje H (1996) Fanconi anemia genes act to suppress a cross-linker-inducible p-53-independent apoptosis pathway in lymphoblastoid cell lines. Blood 87, 938 946.
11. Liu TX, Howlett NG, Deng M, Langenau DM, Hsu K, Rhodes J, Kanki JP, D'Andrea AD, Look AT (2003) Knockdown of zebrafish Fancd2 causes developmental abnormalities via p53-dependent apoptosis. Dev. Cell 5, 903 914.
12. Magdalena N, Pilonetto DV, Bitencourt MA, Pereira NF, Ribeiro RC, Jeng M, Pasquini R (2005) Fraquency of Fanconi anemia in Brazil and efficacy of screening for the FANCA 3788-3790 del mutation. Braz. J. Med. Biol. Res. 38, 669 673.
13. Monti D, Macchioni S, Guido M, Pagano G, Zatterale A, Calzone R, Cossarizza A, Straface E, Malorni W, Franceschi C (1997) Resistance to apoptosis in Fanconi's anaemia. An ex vivo study in peripheral blood mononuclear cells. FEBS Lett. 409, 365 369.
14. Pang Q, Keeble W, Diaz J, Christianson TA, Fagerlie S, Rathbun K, Faulkner GR, O'Dwyer M, Bagby GC Jr. (2001) Role of double-stranded RNA-dependent protein kinase in mediating hypersensitivity of Fanconi anemia complementation group C cells to interferon γ, tumor necrosis factor-α and double-stranded RNA. Blood 97, 1644 1652.
15. Parone PA, James D, Martinou JC (2002) Mitochondria: regulating the inevitable. Biochimie 84, 105 111.
16. Tischkowitz M, Dokal I (2004) Fanconi anaemia and leukaemia - clinical and molecular aspects. Br. J. Haematol. 126, 176 191.
17. Wesselborg S, Kabelitz D (1993) Activation-driven death of human T cell clones: time course kinetics of the induction of cell shrinkage, DNA fragmentation, and cell death. Cell Immunol. 148, 234 241.