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Volumn 37, Issue 8, 2007, Pages 643-650

Insulin does not regulate glucose transport and metabolism in human endothelium

Author keywords

Akt; Endothelial cells; Endothelial NO synthase; Glucose metabolism; Glucose transport; Insulin; Smooth muscle cells

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUCOSE; GLYCOGEN; INSULIN; LACTIC ACID; PROTEIN KINASE B;

EID: 34447318672     PISSN: 00142972     EISSN: 13652362     Source Type: Journal    
DOI: 10.1111/j.1365-2362.2007.01838.x     Document Type: Article
Times cited : (39)

References (28)
  • 1
    • 0036434431 scopus 로고    scopus 로고
    • Insulin regulation of glucose uptake: A complex interplay of intracellular signalling pathways
    • Khan AH, Pessin JE. Insulin regulation of glucose uptake: a complex interplay of intracellular signalling pathways. Diabetologia 2002 45 : 1475 83.
    • (2002) Diabetologia , vol.45 , pp. 1475-83
    • Khan, A.H.1    Pessin, J.E.2
  • 2
    • 27844435600 scopus 로고    scopus 로고
    • Recent developments in the regulation of glucose transporter-4 traffic: New signals, locations and partners
    • Ishiki M, Klip A. Recent developments in the regulation of glucose transporter-4 traffic: new signals, locations and partners. Endocrinology 2005 146 : 5071 8.
    • (2005) Endocrinology , vol.146 , pp. 5071-8
    • Ishiki, M.1    Klip, A.2
  • 3
    • 0020681210 scopus 로고
    • Differential responsiveness to insulin of endothelial and support cells from micro- and macrovessels
    • King GL, Buzney SM, Kahn CR, Hetu N, Buchwald S, Macdonald SG et al. Differential responsiveness to insulin of endothelial and support cells from micro- and macrovessels. J Clin Invest 1983 71 : 974 9.
    • (1983) J Clin Invest , vol.71 , pp. 974-9
    • King, G.L.1    Buzney, S.M.2    Kahn, C.R.3    Hetu, N.4    Buchwald, S.5    MacDonald, S.G.6
  • 4
    • 33645046936 scopus 로고    scopus 로고
    • De novo emergence of insulin-stimulated glucose uptake in human aortic endothelial cells incubated with high glucose
    • Gosmanov AR, Stentz FB, Kitabchi AE. De novo emergence of insulin-stimulated glucose uptake in human aortic endothelial cells incubated with high glucose. Am J Physiol Endocrinol Metab 2006 290 : E516 22.
    • (2006) Am J Physiol Endocrinol Metab , vol.290
    • Gosmanov, A.R.1    Stentz, F.B.2    Kitabchi, A.E.3
  • 5
    • 0024994317 scopus 로고
    • Regulation of hexose transport in aortic endothelial cells by vascular permeability factor and tumor necrosis factor-α, but not by insulin
    • Pekala P, Marlow M, Heuvelman D, Connolly D. Regulation of hexose transport in aortic endothelial cells by vascular permeability factor and tumor necrosis factor-α, but not by insulin. J Biol Chem 1990 265 : 18051 4.
    • (1990) J Biol Chem , vol.265 , pp. 18051-4
    • Pekala, P.1    Marlow, M.2    Heuvelman, D.3    Connolly, D.4
  • 6
    • 27844554767 scopus 로고    scopus 로고
    • Is non-insulin dependent glucose uptake a therapeutic alternative? Part 1: Physiology, mechanisms and role of non insulin-dependent glucose uptake in type 2 diabetes
    • Wiernsperger NF. Is non-insulin dependent glucose uptake a therapeutic alternative? Part 1: physiology, mechanisms and role of non insulin-dependent glucose uptake in type 2 diabetes. Diabetes Metab 2005 31 : 415 26.
    • (2005) Diabetes Metab , vol.31 , pp. 415-26
    • Wiernsperger, N.F.1
  • 7
    • 0025935897 scopus 로고
    • Hexose uptake in primary cultures of bovine brain microvessel endothelial cells. I. Basic characteristics and effects of d-glucose and insulin
    • Takakura Y, Kuentzel SL, Raub TJ, Davies A, Baldwin SA, Borchardt RT. Hexose uptake in primary cultures of bovine brain microvessel endothelial cells. I. Basic characteristics and effects of d-glucose and insulin. Biochim Biophys Acta 1991 1070 : 1 10.
    • (1991) Biochim Biophys Acta , vol.1070 , pp. 1-10
    • Takakura, Y.1    Kuentzel, S.L.2    Raub, T.J.3    Davies, A.4    Baldwin, S.A.5    Borchardt, R.T.6
  • 8
    • 0020660754 scopus 로고
    • Hexose transport in microvascular endothelial cells cultured from bovine retina
    • Betz AL, Bowman PD, Goldstein GW. Hexose transport in microvascular endothelial cells cultured from bovine retina. Exp Eye Res 1983 36 : 269 77.
    • (1983) Exp Eye Res , vol.36 , pp. 269-77
    • Betz, A.L.1    Bowman, P.D.2    Goldstein, G.W.3
  • 9
    • 0023751477 scopus 로고
    • Actions of insulin and insulinlike growth factors I and II in cultured microvessel endothelial cells from bovine adipose tissue
    • Bar RS, Siddle K, Dolash S, Boes M, Dake B. Actions of insulin and insulinlike growth factors I and II in cultured microvessel endothelial cells from bovine adipose tissue. Metabolism 1988 37 : 714 20.
    • (1988) Metabolism , vol.37 , pp. 714-20
    • Bar, R.S.1    Siddle, K.2    Dolash, S.3    Boes, M.4    Dake, B.5
  • 10
    • 0023846415 scopus 로고
    • Glucose starvation is required for insulin stimulation of glucose uptake and metabolism in cultured microvascular endothelial cells
    • Gerritsen ME, Burke TM, Allen LA. Glucose starvation is required for insulin stimulation of glucose uptake and metabolism in cultured microvascular endothelial cells. Microvasc Res 1988 35 : 153 66.
    • (1988) Microvasc Res , vol.35 , pp. 153-66
    • Gerritsen, M.E.1    Burke, T.M.2    Allen, L.A.3
  • 11
    • 16844379366 scopus 로고    scopus 로고
    • Thiazolidinediones inhibit proliferation of microvascular and macrovascular cells by a PPARγ-independent mechanism
    • Artwohl M, Fürnsinn C, Waldhäusl W, Hölzenbein T, Rainer G, Freudenthaler A et al. Thiazolidinediones inhibit proliferation of microvascular and macrovascular cells by a PPARγ-independent mechanism. Diabetologia 2005 48 : 586 94.
    • (2005) Diabetologia , vol.48 , pp. 586-94
    • Artwohl, M.1    Fürnsinn, C.2    Waldhäusl, W.3    Hölzenbein, T.4    Rainer, G.5    Freudenthaler, A.6
  • 12
    • 0035491792 scopus 로고    scopus 로고
    • Direct thiazolidinedione action on isolated rat skeletal muscle fuel handling is independent of peroxisome proliferator-activated receptor-γ-mediated changes in gene expression
    • Brunmair B, Gras F, Neschen S, Roden M, Wagner L, Waldhäusl W et al. Direct thiazolidinedione action on isolated rat skeletal muscle fuel handling is independent of peroxisome proliferator-activated receptor-γ-mediated changes in gene expression. Diabetes 2001 50 : 2309 15.
    • (2001) Diabetes , vol.50 , pp. 2309-15
    • Brunmair, B.1    Gras, F.2    Neschen, S.3    Roden, M.4    Wagner, L.5    Waldhäusl, W.6
  • 13
    • 0018128880 scopus 로고
    • Causes and elimination of erratic blanks in enzymatic metabolite assays involving the use of NAD+ in alkaline hydrazine buffers: Improved conditions for the assay of 1-glutamate, 1-lactate and other metabolites
    • Engel PC, Jones JB. Causes and elimination of erratic blanks in enzymatic metabolite assays involving the use of NAD+ in alkaline hydrazine buffers: Improved conditions for the assay of 1-glutamate, 1-lactate and other metabolites. Anal Biochem 1978 88 : 475 84.
    • (1978) Anal Biochem , vol.88 , pp. 475-84
    • Engel, P.C.1    Jones, J.B.2
  • 14
    • 1342268345 scopus 로고    scopus 로고
    • Free fatty acids trigger apoptosis and inhibit cell cycle progression in human vascular endothelial cells
    • Artwohl M, Roden M, Waldhäusl W, Freudenthaler A, Baumgartner-Parzer SM. Free fatty acids trigger apoptosis and inhibit cell cycle progression in human vascular endothelial cells. FASEB J 2004 18 : 146 8.
    • (2004) FASEB J , vol.18 , pp. 146-8
    • Artwohl, M.1    Roden, M.2    Waldhäusl, W.3    Freudenthaler, A.4    Baumgartner-Parzer, S.M.5
  • 15
    • 0041663621 scopus 로고    scopus 로고
    • Insulin enhances the expression of the endothelial nitric oxide synthase in native endothelial cells: A dual role for AKT and AP-1
    • Fisslthaler B, Benzing T, Busse R, Fleming I. Insulin enhances the expression of the endothelial nitric oxide synthase in native endothelial cells: a dual role for AKT and AP-1. Nitric Oxide 2003 8 : 253 61.
    • (2003) Nitric Oxide , vol.8 , pp. 253-61
    • Fisslthaler, B.1    Benzing, T.2    Busse, R.3    Fleming, I.4
  • 16
    • 33749329784 scopus 로고    scopus 로고
    • Free fatty acids inhibit insulin signaling-stimulated endothelial nitric oxide synthase activation through upregulating PTEN or inhibiting AKT kinase
    • Wang XL, Zhang L, Youker K, Zhang MX, Wang J, LeMaire SA et al. Free fatty acids inhibit insulin signaling-stimulated endothelial nitric oxide synthase activation through upregulating PTEN or inhibiting AKT kinase. Diabetes 2006 55 : 2301 10.
    • (2006) Diabetes , vol.55 , pp. 2301-10
    • Wang, X.L.1    Zhang, L.2    Youker, K.3    Zhang, M.X.4    Wang, J.5    Lemaire, S.A.6
  • 17
    • 33244464562 scopus 로고    scopus 로고
    • Critical nodes in signalling pathways: Insights into insulin action
    • Taniguchi CM, Emanuelli B, Kahn CR. Critical nodes in signalling pathways: insights into insulin action. Nat Rev Mol Cell Biol 2006 7 : 85 96.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 85-96
    • Taniguchi, C.M.1    Emanuelli, B.2    Kahn, C.R.3
  • 18
    • 0033536031 scopus 로고    scopus 로고
    • Differential signaling of insulin and IGF-1 receptors to glycogen synthesis in murine hepatocytes
    • Park BC, Kido Y, Accili D. Differential signaling of insulin and IGF-1 receptors to glycogen synthesis in murine hepatocytes. Biochemistry 1999 38 : 7517 23.
    • (1999) Biochemistry , vol.38 , pp. 7517-23
    • Park, B.C.1    Kido, Y.2    Accili, D.3
  • 19
    • 0038555740 scopus 로고    scopus 로고
    • Functions of insulin and insulin receptor signaling in retina: Possible implications for diabetic retinopathy
    • Reiter CE, Gardner TW. Functions of insulin and insulin receptor signaling in retina: possible implications for diabetic retinopathy. Prog Retin Eye Res 2003 22 : 545 62.
    • (2003) Prog Retin Eye Res , vol.22 , pp. 545-62
    • Reiter, C.E.1    Gardner, T.W.2
  • 20
    • 0035012387 scopus 로고    scopus 로고
    • Oxidative stress impairs insulin internalization in endothelial cells in vitro
    • Bertelsen M, Änggård EE, Carrier MJ. Oxidative stress impairs insulin internalization in endothelial cells in vitro. Diabetologia 2001 44 : 605 13.
    • (2001) Diabetologia , vol.44 , pp. 605-13
    • Bertelsen, M.1    Änggård, E.E.2    Carrier, M.J.3
  • 21
    • 33646178955 scopus 로고    scopus 로고
    • Reciprocal relationships between insulin resistance and endothelial dysfunction. Molecular and pathophysiological mechanisms
    • Kim JA, Montagnani M, Koh KK, Quon MJ. Reciprocal relationships between insulin resistance and endothelial dysfunction. Molecular and pathophysiological mechanisms. Circulation 2006 113 : 1888 904.
    • (2006) Circulation , vol.113 , pp. 1888-904
    • Kim, J.A.1    Montagnani, M.2    Koh, K.K.3    Quon, M.J.4
  • 22
    • 0027395183 scopus 로고
    • Differential regulation of glucose transport and transporters by glucose in vascular endothelial and smooth muscle cells
    • Kaiser N, Sasson S, Feener EP, Boukobza-Vardi N, Higashi S, Moller DE et al. Differential regulation of glucose transport and transporters by glucose in vascular endothelial and smooth muscle cells. Diabetes 1993 42 : 80 9.
    • (1993) Diabetes , vol.42 , pp. 80-9
    • Kaiser, N.1    Sasson, S.2    Feener, E.P.3    Boukobza-Vardi, N.4    Higashi, S.5    Moller, D.E.6
  • 23
    • 0034754105 scopus 로고    scopus 로고
    • Differential glucose uptake in retina- and brain-derived endothelial cells
    • Rajah TT, Olson AL, Grammas P. Differential glucose uptake in retina- and brain-derived endothelial cells. Microvasc Res 2001 62 : 236 42.
    • (2001) Microvasc Res , vol.62 , pp. 236-42
    • Rajah, T.T.1    Olson, A.L.2    Grammas, P.3
  • 24
    • 0028271766 scopus 로고
    • High glucose downregulates glucose transport activity in retinal capillary pericytes but not endothelial cells
    • Mandarino LJ, Finlayson J, Hassell JR. High glucose downregulates glucose transport activity in retinal capillary pericytes but not endothelial cells. Invest Ophthalmol Vis Sci 1994 35 : 964 72.
    • (1994) Invest Ophthalmol Vis Sci , vol.35 , pp. 964-72
    • Mandarino, L.J.1    Finlayson, J.2    Hassell, J.R.3
  • 25
    • 0030979315 scopus 로고    scopus 로고
    • D-glucose stimulates mesangial cell GLUT1 expression and basal and IGF-1-sensitive glucose uptake in rat mesangial cells: Implications for diabetic nephropathy
    • Heilig CW, Liu Y, England RL, Freytag SO, Gilbert JD, Heilig KO et al. d-glucose stimulates mesangial cell GLUT1 expression and basal and IGF-1-sensitive glucose uptake in rat mesangial cells: implications for diabetic nephropathy. Diabetes 1997 46 : 1030 9.
    • (1997) Diabetes , vol.46 , pp. 1030-9
    • Heilig, C.W.1    Liu, Y.2    England, R.L.3    Freytag, S.O.4    Gilbert, J.D.5    Heilig, K.O.6
  • 26
    • 0035217192 scopus 로고    scopus 로고
    • Increased renal GLUT1 abundance and urinary TGF-β1 in streptozotocin-induced diabetic rats. implications for the development of nephropathy complicating diabetes
    • D'Agord Schaan B, Lacchini S, Bertoluci MC, Irigoyen MC, Machado UF, Schmid H. Increased renal GLUT1 abundance and urinary TGF-β1 in streptozotocin-induced diabetic rats. implications for the development of nephropathy complicating diabetes. Horm Metab Res 2001 33 : 664 9.
    • (2001) Horm Metab Res , vol.33 , pp. 664-9
    • D'Agord Schaan, B.1    Lacchini, S.2    Bertoluci, M.C.3    Irigoyen, M.C.4    MacHado, U.F.5    Schmid, H.6


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