Quantitative nuclear magnetic resonance spectroscopic determination of the oxyethylene group content of polysorbates

Food Additives and Contaminants

Volumn 24, Issue 8, 2007, Pages 799-806

  Sugimoto, Naoki ^a   Koike, Ryo ^b   Furusho, Noriko ^a   Tanno, Makoto ^b   Yomota, Chikako ^a   Sato, Kyoko ^a   Yamazaki, Takeshi ^a   Tanamoto, Kenichi ^a  

^a NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^b KAO CORPORATION   (Japan)

Author keywords

Analytical method; Food additive; Oxyethylene; Polysorbate; Quantitative nuclear magnetic resonance

Indexed keywords

ETHYLENE DERIVATIVE; MACROGOL DERIVATIVE; POLYMER; POLYSORBATE; POLYSORBATE 20; POLYSORBATE 60; POLYSORBATE 80; POTASSIUM HYDROXIDE; SORBITAN OLEATE;

ARTICLE; CHEMICAL STRUCTURE; CONTROLLED STUDY; COST BENEFIT ANALYSIS; MOLECULAR WEIGHT; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; QUANTITATIVE ANALYSIS; VALIDATION PROCESS;

ETHYLENE OXIDE; FOOD ADDITIVES; MAGNETIC RESONANCE SPECTROSCOPY; POLYSORBATES; SURFACE-ACTIVE AGENTS;

EID: 34447315835     PISSN: 0265203X     EISSN: 14645122     Source Type: Journal    
DOI: 10.1080/02652030701278347     Document Type: Article

References (14)

1. Frison-Norrie, S. and Sporns, P. (2001) Investigating the molecular heterogeneity of polysorbate emulsifiers by MALDI-TOF MS. Journal of Agricultural and Food Chemistry, 49, pp. 3335-3340.
2. Jake, B., Sticher, O., Veit, M., Fröhlich, R. and Paili, GF (2002) Evaluation of glucoiberin reference material from Iberis amara by spectroscopic fingerprinting. Journal of Natural Products, 65, pp. 517-522.
3. Jancke, H. (1998) NMR spectroscopy as a primary analytical method.
4. Joint FAO/WHO Expert Committee on Food Additives (JECFA)
5. 1H nuclear magnetic resonance using an internal standard. Bunseki Kagaku (The Japan Society for Analytical Chemistry), 53, pp. 1125-1131.
6. 1H nuclear magnetic resonance using an internal standard. Bunseki Kagaku (The Japan Society for Analytical Chemistry), 53, pp. 1133-1138.
7. 1H nuclear magnetic resonance using an internal standard. Bunseki Kagaku (The Japan Society for Analytical Chemistry), 54, pp. 715-722.
8. Paula, GF (2001) qNMR - a versatile concept for the validation of natural product reference compounds. Phytochemical Analysis, 12, pp. 28-42.
9. 1H NMR: Development and potential of a method for natural products analysis. Journal of Natural Products, 68, pp. 133-149.
10. 1H nuclear magnetic resonance. Bunsaki Kagaku (The Japan Society for Analytical Chemistry), 52, pp. 1029-1036.
11. Saito, T., Nakaie, S., Kinoshita, M., Ihara, T., Kinugasa, S., Nomura, A. and Maeda, T. (2004) Practical guide for accurate quantitative solution state NMR analysis. Metrologia, 41, pp. 213-218.
12. Stefanova, R., Rankoff, D., Panayotova, S. and Spassov, SL (1988) Quantitative proton NMR determination of linoleic acid mono- and diester of polyethyleneglycols via reaction with trichloroacetyl isocyanate. Journal of American Oil Chemists' Society, 65, pp. 1516-1518.
13. Dang, HV Vu, Gray, AI, Watson, D., Bates, CD, Scholes, P. and Gillian, GM (2006) Composition analysis of two batches of polysorbate 60 using MS and NMR techniques. Journal of Pharmaceutical and Biomedical Analysis, 40, pp. 1155-1165.
14. Wells, RJ, Hook, JM, Al-Deen, TS and Hibbert, DB (2002) Quantitative nuclear magnetic resonance (QNMR) spectroscopy for assessing the purity of technical grade agrochemicals: 2,4-Dichlorophenoxyacetic acid (2,4-) and sodium 2,2-dichloropropionate (dalapon sodium). Journal of Agricultural and Food Chemistry, 50, pp. 3366-3374.