QSAR studies for the inhibition of the transmembrane isozymes XII and XIV of human carbonic anhydrase with a series of sulfonamides

Bioorganic and Medicinal Chemistry

Volumn 15, Issue 17, 2007, Pages 5666-5671

  Tarko, Laszlo ^a   Supuran, Claudiu T ^b  

^a INSTITUTE OF ORGANIC CHEMISTRY   (Romania)

^b UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Carbonic anhydrase; Isozymes XII and XIV; Lead scaffold hopping; QSAR; Sulfonamides

Indexed keywords

BENZENESULFONAMIDE DERIVATIVE; CARBONATE DEHYDRATASE; ISOENZYME; SULFONAMIDE;

ARTICLE; DRUG DESIGN; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME INHIBITION; MODEL; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

CARBONIC ANHYDRASE INHIBITORS; CARBONIC ANHYDRASES; HUMANS; ISOENZYMES; MOLECULAR STRUCTURE; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; SULFONAMIDES;

EID: 34447300989     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2007.06.009     Document Type: Article

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