Pre-stem cell transplantation enzyme replacement therapy in Hurler syndrome does not lead to significant antibody formation or delayed recovery of the endogenous enzyme post-transplant: A case report

Pediatric Transplantation

Volumn 11, Issue 5, 2007, Pages 563-567

  Soni, Sandeep ^a   Hente, Monica ^b   Breslin, Nancy ^b   Hersh, Joseph ^b   Whitley, Chester ^c   Cheerva, Alexandra ^b   Bertolone, Salvatore ^b  

^a NATIONWIDE CHILDREN S HOSPITAL   (United States)

^b University of Louisville School of Medicine   (United States)

^c UNIVERSITY OF MINNESOTA MEDICAL CENTER   (United States)

Author keywords

Alpha L iduronidase (Aldurazyme); Glycosaminoglycans; Mucopolysaccharidosis; Stem cell transplantation

Indexed keywords

BUSULFAN; CYCLOPHOSPHAMIDE; GLYCOSAMINOGLYCAN; LARONIDASE; LEVO IDURONIDASE; TACROLIMUS; THYMOCYTE ANTIBODY;

ANTIBODY PRODUCTION; AREA UNDER THE CURVE; ARTICLE; BONE MARROW TRANSPLANTATION; CASE REPORT; ECHOCARDIOGRAPHY; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME REPLACEMENT; FOOD AND DRUG ADMINISTRATION; GRAFT VERSUS HOST REACTION; HEARING LOSS; HUMAN; HURLER SYNDROME; KYPHOSIS; LEUKOCYTE COUNT; LUNG DISEASE; MALE; POLYSOMNOGRAPHY; PRESCHOOL CHILD; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SLEEP APNEA SYNDROME; SPLENOMEGALY; STEM CELL TRANSPLANTATION; TRACHEOSTOMY;

ANTIBODY FORMATION; CHILD, PRESCHOOL; FOLLOW-UP STUDIES; HUMANS; IDURONIDASE; MALE; MUCOPOLYSACCHARIDOSIS I; PREOPERATIVE CARE; RECOMBINANT PROTEINS; RECOVERY OF FUNCTION; STEM CELL TRANSPLANTATION;

EID: 34447296772     PISSN: 13973142     EISSN: 13993046     Source Type: Journal    
DOI: 10.1111/j.1399-3046.2007.00720.x     Document Type: Article

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