Relationship of cholesterol and apolipoprotein E promoter-491 A/T polymorphisms to beta-amyloid deposition in Alzheimer disease

Journal of Clinical Rehabilitative Tissue Engineering Research

Volumn 11, Issue 21, 2007, Pages 4159-4162

  Liu, Fang ^a,b   Zhao, Y H ^b  

^a SHENYANG MEDICAL COLLEGE   (China)

^b South Carolina State Museum   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; AMYLOID BETA PROTEIN; APOLIPOPROTEIN E; CHOLESTEROL; GENOMIC DNA; RESTRICTION ENDONUCLEASE; THYMINE;

ALZHEIMER DISEASE; ARTICLE; BRAIN LEVEL; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DNA EXTRACTION; DNA POLYMORPHISM; ELECTROPHORESIS; GENE AMPLIFICATION; GENE LOCUS; GENOTYPE; HUMAN; LIVER PARENCHYMA; MAJOR CLINICAL STUDY; POLYMERASE CHAIN REACTION; PROMOTER REGION;

EID: 34447295364     PISSN: 16738225     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Bobkova D,Honsova E,Kovar J,et al.Effect of diets on lipoprotein concentrations in heterozygous apolipoprotein E-deficient mice. Physiol Res 2004;53(6):635-643
2. Bossy-Wetzel E,Schwarzenbacher R,Lipton S.Molecular pathways to neurodegeneration. Nat Med 2004;10 Suppl:S2-S9
3. Lambert JC,Mann D,Richard F,et al.Is there a relation between APOE expression and brain amyloid load in Alzheimers disease? J Neurol Neurosurg Psychiatry 2005;76(7):928-933
4. Lambert JC,Araria-Goumidi L,Myllykangas L,et al.Contribution of APOE promoter polymorphisms to Alzheimer's disease risk.Neurology 2002;59 (1):59-66
5. Lambert JC,Berr C,Cottel D,et al.APOE promoter polymorphisms and dementia in the elderly.Neurosci Lett 2004;365(2):116-119
6. Chartier-Harlin MC,Araria-Goumidi L,Lambert JC.Genetic complexity of Alzheimer's disease.Rev Neurol (Paris) 2004;160(2):251-255
7. Lambert JC,Coyle N,Lendon C.The allelic modulation of apolipoprotein E expression by oestrogen: potential relevance for Alzheimers disease.J Med Genet 2004;41(2):104-112
8. Lambert JC,Mann D,Harris J,et al.Association study of Notch 4 polymorphisms with Alzheimer's disease.J Neurol Neurosurg Psychiatry 2004;75(3):377-381
9. Debette S,Lambert JC,Gariepy J,et al.New insight into the association of apolipoprotein E genetic variants with carotid plaques and intima-media thickness.Stroke 2006;37(12):2917-2923
10. Lambert JC,Araria-Goumidi L,Myllykangas L,et al.Contribution of APOE promoter polymorphisms to Alzheimer's disease risk.Neurology 2002;59 (1):59-66
11. Lautenschlager NT,Wu JS,Laws SM,et al.Neurological soft signs are associated with APOE genotype, age and cognitive performance.J Alzheimers Dis 2005;7(4):325-330
12. Ozelo MC,Costa DS,Siqueira LH,et al.Genetic variability of platelet glycoprotein Ibalpha gene.Am J Hematol 2004;77(2):107-116
13. Ulrichts H,Vanhoorelbeke K,Cauwenberghs S,et al.von Willebrand factor but not alpha-thrombin binding to platelet glycoprotein Ibalpha is influenced by the HPA-2 polymorphism. Arterioscler Thromb Vasc Biol 2003;23(7):1302-1307
14. Laws SM,Hone E,Taddei K,et al.Variation at the APOE 491 promoter locus is associated with altered brain levels of apolipoprotein E.Mol Psychiatry 2002;7(8):886-890
15. Laws SM,Clarnette RM,Taddei K.APOE-epsilon4 and APOE -491A polymorphisms in individuals with subjective memory loss.Mol Psychiatry 2002;7(7):768-775
16. Laws SM,Clarnette RM,Taddei K,et al.APOE-epsilon4 and APOE -491A polymorphisms in individuals with subjective memory loss.Mol Psychiatry 2002;7(7):768-775
17. Laws SM,Taddei K,Martins G,et al.The -491AA polymorphism in the APOE gene is associated with increased plasma apoE levels in Alzheimer's disease.Neuroreport 1999;10(4):879-882
18. Laws SM,Clarnette RM,Taddei K,et al.Association between the presenilin-1 mutation Glu318Gly and complaints of memory impairment. Neurobiol Aging 2002;23(1):55-58
19. Laws SM,Perneczky R,Wagenpfeil S,et al.TNF polymorphisms in Alzheimer disease and functional implications on CSF beta-amyloid levels.Hum Mutat 2005;26(1):29-35
20. Burkhardt MS,Foster JK,Laws SM.Oestrogen replacement therapy may improve memory functioning in the absence of APOE epsilon4.J Alzheimers Dis 2004;6(3):221-228