Arsenic trioxide-mediated growth inhibition in gallbladder carcinoma cells via down-regulation of Cyclin D1 transcription mediated by Sp1 transcription factor

Biochemical and Biophysical Research Communications

Volumn 360, Issue 3, 2007, Pages 684-689

  Ai, Zhilong ^a   Lu, Weiqi ^a   Ton, Saixiong ^a   Liu, Houbao ^a   Sou, Tao ^a   Shen, Zhenbin ^a   Qin, Xinyu ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Arsenic trioxide; Cell growth; Cyclin D1; Gallbladder carcinoma; Sp1

Indexed keywords

ARSENIC TRIOXIDE; CYCLIN D1; TRANSCRIPTION FACTOR SP1;

ARTICLE; CANCER CELL; CANCER INHIBITION; CELL CYCLE; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; GALLBLADDER CARCINOMA; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN FUNCTION;

ARSENICALS; CARCINOMA; CELL LINE, TUMOR; CYCLIN D1; DOWN-REGULATION; GALLBLADDER NEOPLASMS; HUMANS; OXIDES; SP1 TRANSCRIPTION FACTOR; TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 34447275279     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.06.123     Document Type: Article

References (28)

1. Donohue J.H. Present status of the diagnosis and treatment of gallbladder carcinoma. J. Hepatobiliary Pancreat. Surg. 8 (2001) 530-534
2. Shukla V.K., Prakash A., Chauhan V.S., Singh S., and Puneet S. Biliary nitrate and risk of carcinoma of the gallbladder. Eur. J. Cancer Prev. 13 (2004) 355-356
3. Zhu X.H., Shen Y.L., Jing Y.K., Cai X., Jia P.M., Huang Y., Tang W., Shi G.Y., Sun Y.P., Dai J., Wang Z.Y., Chen S.J., Zhang T.D., Waxman S., Chen Z., and Chen G.Q. Apoptosis and growth inhibition in malignant lymphocytes after treatment with arsenic trioxide at clinically achievable concentrations. J. Natl. Cancer Inst. 91 (1999) 772-778
4. 3 induces NB4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PML-RAR alpha/PML proteins. Blood 88 (1996) 1052-1061
5. Antman K.H. Introduction: the history of arsenic trioxide in cancer therapy. Oncologist 6 Suppl. 2 (2001) 1-2
6. Shen Y., Shen Z.X., Yan H., Chen J., Zeng X.Y., Li J.M., Li X.S., Wu W., Xiong S.M., Zhao W.L., Tang W., Wu F., Liu Y.F., Niu C., Wang Z.Y., Chen S.J., and Chen Z. Studies on the clinical efficacy and pharmacokinetics of low-dose arsenic trioxide in the treatment of relapsed acute promyelocytic leukemia: a comparison with conventional dosage. Leukemia 15 (2001) 735-741
7. 3) in the orthotopic metastasis model of androgen-independent prostate cancer. Cancer Res. 61 (2001) 5432-5440
8. Uslu R., Sanli U.A., Sezgin C., Karabulut B., Terzioglu E., Omay S.B., and Goker E. Arsenic trioxide-mediated cytotoxicity and apoptosis in prostate and ovarian carcinoma cell lines. Clin. Cancer Res. 6 (2000) 4957-4964
9. Seol J.G., Park W.H., Kim E.S., Jung C.W., Hyun J.M., Kim B.K., and Lee Y.Y. Effect of arsenic trioxide on cell cycle arrest in head and neck cancer cell line PCI-1. Biochem. Biophys. Res. Commun. 265 (1999) 400-404
10. Ai Z., Lu W., and Qin X. Arsenic trioxide induces gallbladder carcinoma cell apoptosis via downregulation of Bcl-2. Biochem. Biophys. Res. Commun. 348 (2006) 1075-1081
11. Hilton T.L., Li Y., Dunphy E.L., and Wang E.H. TAF1 histone acetyltransferase activity in Sp1 activation of the cyclin D1 promoter. Mol. Cell. Biol. 25 (2005) 4321-4332
12. Jiang J., Shen J., Wu T., Wei Y., Chen X., Zong H., Zhang S., Sun M., Xie J., Kong X., Yang Y., Shen A., Wang H., and Gu J. Down-regulation of beta1,4-galactosyltransferase V is a critical part of etoposide-induced apoptotic process and could be mediated by decreasing Sp1 levels in human glioma cells. Glycobiology 16 (2006) 1045-1051
13. Zhu X., Jiang J., Shen H., Wang H., Zong H., Li Z., Yang Y., Niu Z., Liu W., Chen X., Hu Y., and Gu J. Elevated beta1,4-galactosyltransferase I in highly metastatic human lung cancer cells. Identification of E1AF as important transcription activator. J. Biol. Chem. 280 (2005) 12503-12516
14. Knudsen K.E., Diehl J.A., Haiman C.A., and Knudsen E.S. Cyclin D1: polymorphism, aberrant splicing and cancer risk. Oncogene 25 (2006) 1620-1628
15. Fukami-Kobayashi J., and Mitsui Y. The regulation of cyclin D1 expression in senescent human fibroblasts. Exp. Cell Res. 241 (1998) 435-444
16. Bartusel T., Schubert S., and Klempnauer K.H. Regulation of the cyclin D1 and cyclin A1 promoters by B-Myb is mediated by Sp1 binding sites. Gene 351 (2005) 171-180
17. Lee C., Lin Y., Huang M., Lin C., Liu C., Chow J., and Liu H.E. Increased cellular glutathione and protection by bone marrow stromal cells account for the resistance of non-acute promylocytic leukemia acute myeloid leukemia cells to arsenic trioxide in vivo. Leuk. Lymphoma 47 (2006) 521-529
18. Shen Z.Y., Shen J., Cai W.J., Hong C., and Zheng M.H. The alteration of mitochondria is an early event of arsenic trioxide induced apoptosis in esophageal carcinoma cells. Int. J. Mol. Med. 5 (2000) 155-158
19. 3) on human megakaryocytic leukemia cell lines. With a comparison of its effects on other cell lineages. Leuk. Lymphoma 38 (2000) 153-163
20. Roy P.G., and Thompson A.M. Cyclin D1 and breast cancer. Breast 15 (2006) 718-727
21. Fan Y.Z., Fu J.Y., Zhao Z.M., and Chen C.Q. Inhibitory effect of norcantharidin on the growth of human gallbladder carcinoma GBC-SD cells in vitro. Hepatobiliary Pancreat Dis. Int. 6 (2007) 72-80
22. Ma H.B., Hu H.T., Di Z.L., Wang Z.R., Shi J.S., Wang X.J., and Li Y. Association of cyclin D1, p16 and retinoblastoma protein expressions with prognosis and metastasis of gallbladder carcinoma. World J. Gastroenterol. 11 (2005) 744-747
23. Tsuchida A., Itoi T., Aoki T., and Koyanagi Y. Carcinogenetic process in gallbladder mucosa with pancreaticobiliary maljunction (Review). Oncol. Rep. 10 (2003) 1693-1699
24. Hui A.M., Li X., Shi Y.Z., Takayama T., Torzilli G., and Makuuchi M. Cyclin D1 overexpression is a critical event in gallbladder carcinogenesis and independently predicts decreased survival for patients with gallbladder carcinoma. Clin. Cancer Res. 6 (2000) 4272-4277
25. Kavurma M.M., and Khachigian L.M. Sp1 inhibits proliferation and induces apoptosis in vascular smooth muscle cells by repressing p21WAF1/Cip1 transcription and cyclin D1-Cdk4-p21WAF1/Cip1 complex formation. J. Biol. Chem. 278 (2003) 32537-32543
26. Aggarwal B.B., and Ichikawa H. Molecular targets and anticancer potential of indole-3-carbinol and its derivatives. Cell Cycle 4 (2005) 1201-1215
27. Opitz O.G., and Rustgi A.K. Interaction between Sp1 and cell cycle regulatory proteins is important in transactivation of a differentiation-related gene. Cancer Res. 60 (2000) 2825-2830
28. Grinstein E., Jundt F., Weinert I., Wernet P., and Royer H.D. Sp1 as G1 cell cycle phase specific transcription factor in epithelial cells. Oncogene 21 (2002) 1485-1492