The stable 2-kilobase latency-associated transcript of herpes simplex virus type 1 can alter the assembly of the 60S ribosomal subunit and is exported from nucleus to cytoplasm by a CRM1-dependent pathway

Journal of Virology

Volumn 81, Issue 14, 2007, Pages 7695-7701

  Atanasiu, Doina ^a   Fraser, Nigel W ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EXPORTIN 1; LATENCY ASSOCIATED PEPTIDE; RIBOSOME PROTEIN;

ARTICLE; CONTROLLED STUDY; CYTOPLASM; HERPES SIMPLEX VIRUS 1; HUMAN; HUMAN CELL; INTRON; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; PROTEIN TRANSPORT; VIRUS LATENCY;

BIOLOGICAL TRANSPORT; CELL LINE; CELL NUCLEUS; CYTOPLASM; HERPESVIRUS 1, HUMAN; HUMANS; INTRONS; KARYOPHERINS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RIBOSOMES; RNA, MESSENGER;

HUMAN HERPESVIRUS 1;

EID: 34447267211     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.00282-07     Document Type: Article

References (30)

1. Ahmed, M., and N. W. Fraser. 2001. The herpes simplex virus type-1 2-kb latency-associated transcript intron associates with ribosomal proteins and splicing factors in vivo. J. Virol. 75:12070-12080.
2. Aitchison, J. D., and M. P. Rout. 2000. The road to ribosomes. Filling potholes in the export pathway. J. Cell Biol. 151:F23-F26.
3. Bachellerie, J. P., J. Cavaille, and A. Huttenhofer. 2002. The expanding snoRNA world. Biochimie 84:775-790.
4. Charollais, J., M. Dreyfus, and I. lost. 2004. CsdA, a cold-shock RNA helicase from Escherichia coli, is involved in the biogenesis of 50S ribosomal subunit. Nucleic Acids Res. 32:2751-2759.
5. Charollais, J., D. Pflieger, J. Vinh, M. Dreyfus, and I. Iost. 2003. The DEAD-box RNA helicase SrmB is involved in the assembly of 50S ribosomal subunits in Escherichia coli. Mol. Microbiol. 48:1253-1265.
6. Farrell, M. J., A. T. Dobson, and L. T. Feldman. 1991. Herpes simplex virus latency-associated transcript is a stable intron. Proc. Natl. Acad. Sci. USA 88:790-794.
7. Goldenberg, D., N. Mador, M. J. Ball, A. Panet, and I. Steiner. 1997. The abundant latency-associated transcripts of herpes simplex virus type 1 are bound to polyribosomes in cultured neuronal cells and during latent infection in mouse trigeminal ganglia. J. Virol. 71:2897-2904.
8. Goldenberg, D., N. Mador, A. Panet, and I. Steiner. 1998. Tissue specific distribution of the herpes simplex virus type 1 latency-associated transcripts on polyribosomes during latent infection. J. Neurovirol. 4:426-432.
9. Johnson, A. W., E. Lund, and J. Dahlberg. 2002. Nuclear export of ribosomal subunits. Trends Biochem. Sci. 27:580-585.
10. Jones, P. G., M. Mitta, Y. Kim, W. Jiang, and M. Inouye. 1996. Cold shock induces a major ribosomal-associated protein that unwinds double-stranded RNA in Escherichia coli. Proc. Natl. Acad. Sci. USA 93:76-80.
11. Krummenacher, C., J. M. Zabolotny, and N. W. Fraser. 1997. Selection of a nonconsensus branch point is influenced by an RNA stem-loop structure and is important to confer stability to the herpes simplex virus 2-kilobase latency-associated transcript. J. Virol. 71:5849-5861.
12. Kudo, N., N. Matsumori, H. Taoka, D. Fujiwara, E. P. Schreiner, B. Wolff, M. Yoshida, and S. Horinouchi. 1999. Leptomycin B inactivates CRM1/ exportin 1 by covalent modification at a cysteine residue in the central conserved region. Proc. Natl. Acad. Sci. USA 96:9112-9117.
13. Kulesza, C. A., and T. Shenk. 2004. Human cytomegalovirus 5-kilobase immediate-early RNA is a stable intron. J. Virol. 78:13182-13189.
14. Lamond, A. I., and J. E. Sleeman. 2003. Nuclear substructure and dynamics. Curr. Biol. 13:R825-R828.
15. Lock, M., C. Miller, and N. W. Fraser. 2001. Analysis of protein expression from within the region encoding the 2.0-kilobase latency-associated transcript of herpes simplex virus type 1. J. Virol. 75:3413-3426.
16. Maggioncalda, J., A. Mehta, Y. H. Su, N. W. Fraser, and T. M. Block. 1996. Correlation between herpes simplex virus type 1 rate of reactivation from latent infection and the number of infected neurons in trigeminal ganglia. Virology 225:72-81.
17. Nazar, R. N. 2004. Ribosomal RNA processing and ribosome biogenesis in eukaryotes. IUBMB Life 56:457-465.
18. Nicosia, M., J. M. Zabolotny, R. P. Lirette, and N. W. Fraser. 1994. The HSV-1 2 kb latency-associated transcript is found in the cytoplasm comigrating with ribosomal subunits during productive infection. Virology 204: 717-728.
19. Saveanu, C., D. Bienvenu, A. Namane, P. E. Gleizes, N. Gas, A. Jacquier, and M. Fromont-Racine. 2001. Nog2p, a putative GTPase associated with pre-60S subunits and required for late 60S maturation steps. EMBO J. 20:6475-6484.
20. Spivack, J. G., G. M. Woods, and N. W. Fraser. 1991. Identification of a novel latency-specific splice donor signal within the herpes simplex virus type 1 2.0-kilobase latency-associated transcript (LAT): translation inhibition of LAT open reading frames by the intron within the 2.0-kilobase LAT. J. Virol. 65:6800-6810.
21. Stevens, J. G., E. K. Wagner, G. B. Devi-Rao, M. L. Cook, and L. T. Feldman. 1987. RNA complementary to a herpesvirus alpha gene mRNA is prominent in latently infected neurons. Science 235:1056-1059.
22. Strezoska, Z., D. G. Pestov, and L. F. Lau. 2000. Bop1 is a mouse WD40 repeat nucleolar protein involved in 28S and 5.8S rRNA processing and 60S ribosome biogenesis. Mol. Cell. Biol. 20:5516-5528.
23. Thomas, D. L., M. Lock, J. M. Zabolotny, B. R. Mohan, and N. W. Fraser. 2002. The 2-kilobase intron of the herpes simplex virus type 1 latency-associated transcript has a half-life of approximately 24 hours in SY5Y and COS-1 cells. J. Virol. 76:532-540.
24. Thomas, F., and U. Kutay. 2003. Biogenesis and nuclear export of ribosomal subunits in higher eukaryotes depend on the CRM1 export pathway. J. Cell Sci. 116:2409-2419.
25. Thomas, S. K., C. E. Lilley, D. S. Latchman, and R. S. Coffin. 2002. A protein encoded by the herpes simplex virus (HSV) type 1 2-kilobase latency-associated transcript is phosphorylated, localized to the nucleus, and overcomes the repression of expression from exogenous promoters when inserted into the quiescent HSV genome. J. Virol. 76:4056-4067.
26. Tomasevic, N., and B. Peculis. 1999. Identification of a U8 snoRNA-specific binding protein. J. Biol. Chem. 274:35914-35920.
27. Wilson, G. N., L. L. Szura, C. Rushford, D. Jackson, and J. Erickson. 1982. Structure and variation of human ribosomal DNA: the external transcribed spacer and adjacent regions. Am. J. Hum. Genet. 34:32-49.
28. Wolfe, J. H., S. L. Deshmane, and N. W. Fraser. 1992. Herpesvirus vector gene transfer and expression of β-glucuronidase in the central nervous system of MPS VII mice. Nat. Genet. 1:379-384.
29. Zabolotny, J. M., C. Krummenacher, and N. W. Fraser. 1997. The herpes simplex virus type 1 2.0-kilobase latency-associated transcript is a stable intron which branches at a guanosine. J. Virol. 71:4199-4208.
30. Zhao, J., M. Kessler, S. Helmling, J. P. O'Connor, and C. Moore. 1999. Pta1, a component of yeast CF II, is required for both cleavage and poly(A) addition of mRNA precursor. Mol. Cell. Biol. 19:7733-7740.