Dose ranging study of gabapentin for postoperative pain after myomectomy;Studio di diversi dosaggi di gabapentin nel trattamento del dolore postoperatorio dopo miomectomia

Acta Anaesthesiologica Italica / Anaesthesia and Intensive Care in Italy

Volumn 58, Issue 1, 2007, Pages 23-34

  Said Ahmed, Hani Abdel Fattah ^a,b  

^a AIN SHAMS UNIVERSITY   (Egypt)

^b NONE   (Egypt)

Author keywords

Gabapentin; Myomectomy; Postoperative pain

Indexed keywords

FENTANYL; GABAPENTIN; PLACEBO;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIZZINESS; DRUG DOSE INCREASE; HUMAN; INCIDENCE; MYOMECTOMY; NAUSEA; POSTOPERATIVE PAIN; RANDOMIZED CONTROLLED TRIAL; SOMNOLENCE; VISUAL ANALOG SCALE; VISUAL DISORDER; VOMITING;

EID: 34447263823     PISSN: 11248882     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Portenoy RK. Tolerance to opioid analgesics: clinical aspects. Cancer Surv. 1994; 21: 49-65.
2. Dickenson A. Neurophysiology of opioid poorly responsive pain. Cancer Surv. 1994; 21: 5-16.
3. Fishman S, Borsook D. Opioid in pain management, Essential of pain medicine and regional anesthesia. Edited by Benzon H, Raja S, Molloy RE, Strichartz G. New York, Churchill Livingstone, 1999; 51-4.
4. Rosner H, Rubin L, Kestenbaum A. Gabapentin adjunctive therapy in neuropathic pain states. Clin J Pain 1996; 12: 56-8.
5. Backonja M, Beydoun A, Edwards KR. Gabapentin for the symptomatic treatment of painful neuropathy in patients with diabetes mellitus: a randomized controlled trial. JAMA 1998; 280: 1831-6.
6. Rowbotham M, Harden N, Stacey B. Gabapentin for the treatment of post herpetic neuralgia: a randomized controlled trial. JAMA 1998; 280: 1837-42.
7. Mellick GA, Mellick LB. Reflex sympathetic dystrophy treated with gabapentin. Arch Phys Med Rehabil 1997; 78: 98-105.
8. Taylor CP, Gee NS, Su TZ, Kocsis JD, Wetly DF, Brown JP, Dooley DJ, Boden P, Singh L. A summary of mechanistic hypothesis of gabapentin pharmacology. Epilepsy Res 1998; 29: 233-249.
9. Driks J, Petersen KL, Rowbotham MC, Dahl JB. Gabapentin suppresses cutaneaus hyperalgesia following heat/ capsaicin sensitization. Anesthesiology 2002; 97: 102-6.
10. Goa KL, Sorkin EM. Gabapentin. A review of its pharmacological properties and clinical potential in epilepsy. Drug 1993; 46: 409-27.
11. Woolf CJ, Chong MS. Preemptive analgesia - treating postoperative pain by preventing the establishment of central sensitization. Anesth Analg 1993; 77: 362-79.
12. Kissin I. Preemptive analgesia. Anesthesiology 2000; 93: 1138-43.
13. Dirks J, Fredenshorg BB, Fomsgaard JS, Flyger H, Dahl JB. A randomized study of the effects of single dose gabapentin versus placebo on postoperative pain and morphine consumption after mastectomy. Anesthesiology 2002; 95: 985-91.
14. Fassoulaki A, Patris K, Sarantopoulos C, Hogan Q. The analgesic effect of gabapentin and mexiletine after breast surgery for cancer. Anesth Analg 2002; 95: 985-91.
15. Pandey CK, Sabay S, Gupta D. Preemptive gabapentin decreases postoperative pain after lumber discoidectomy. Cand J Anesth 2004; 51: 986-9.
16. Gee NS, Brown LP, Dissanayake VU, Offord J, Thurlow R, Woodruff. The novel anticonvulsant drug, gabapentin, bind to the alpha 2delta subunit of a calcium channel. J Biol Chem 1996; 271: 5768-76.
17. Luo ZD, Chaplan SR, Higuera ES, Sorkin JS, Stauderman KA, William ME, Yaksh TL. Up regulation of dorsal root ganglion (alpha)2 (delta) calcium channel subunit and its correlation with allodynia in spinal nerve injured rats. J Neurosci 2001; 21: 1868-75.
18. Maneuf Y, McKnight A. Block by gabapentine of the facilitation of glutamate release from rat trigeminal nucleous following activation of protein kinase c or adenyl cyclase. Br J Pharmacol 2001; 134: 237-40.
19. Hurley RW, Chatterjea D, Feng RM, and Taylor CP. Gabapentin and pregabalin can interact synergistically with naproxen to produce antihyperalgesia. Anesthesiology 2002; 97: 1263-73.
20. Gilron I, Biederman L, Jhamandas K, Hong M. Gabapentin blocks and reverses antinociceptive morphine tolerance in the rat paw-pressure and tail-flick tests. Anesthesiology 2003; 98: 1288-92.
21. Dierking G, Duedahl H, Rasmussen ML, Fomsgaard JS. Effects of gabapentin on postoperative morphine consumption and pain after abdominal hysterectomy: a randomized, double-blind trial. Acta Anaesthesiol Scand 2004; 48: 322-327.
22. Feng Y, Cui M, Willis WD. Gabapentin markedly reduces acetic acid-induced visceral nociception. Anesthesiology 2003; 98: 729-33.
23. Al-Mujadi H, A-Refai A, Katzarov MG. Preemptive gabapentine reduces postoperative pain and opioid demand following thyroid surgery. Canad J Anesth 2006; 53: 268-73.
24. Rorarius MG, Mennander S, Suominen P. Gabapentin for the prevention of postoperative pain after vaginal hysterectomy. Pain 2004; 110: 175-81.
25. Mao J, Chen LL. Gabapentin in pain management. Anesth analg 2000; 91: 680-7.
26. Mclean MJ, Morrell MJ, Wilmore LJ, Privitera MD. Safety and tolerability of gabapentin as adjunctive therapy in a large, multicenter study. Epilepsia 1999; 40: 965-72.