Design, synthesis, and evaluation of potential inhibitors of brassinin glucosyltransferase, a phytoalexin detoxifying enzyme from Sclerotinia sclerotiorum

Bioorganic and Medicinal Chemistry

Volumn 15, Issue 17, 2007, Pages 5981-5996

  Pedras, M Soledade C ^a   Hossain, Mohammad ^a  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

Author keywords

Antifungal; Brassinin; Brassinin glucosyltransferase; Detoxifying enzyme; Dithiocarbamate; Paldoxin; Phytoalexin; Sclerotinia sclerotiorum

Indexed keywords

3 PHENYLINDOLE; 5 FLUOROCAMALEXIN; 6 FLUORO 3 PHENYLINDOLE; BENZOFURAN DERIVATIVE; BRASSILEXIN; BRASSININ; BRASSININ GLUCOSYLTRANSFERASE; CAMALEXIN; DITHIOCARBAMIC ACID DERIVATIVE; GLUCOSE DERIVATIVE; GLUCOSYLTRANSFERASE; INDOLE DERIVATIVE; METHYL(BENZOFURAN 2 YL)METHYLDITHIOCARBAMATE; METHYL(BENZOFURAN 3 YL)METHYLDITHIOCARBAMATE; METHYL(INDOL 2 YL)METHYLDITHIOCARBAMATE; NITROGEN; PHYTOALEXIN; SINALEXIN; UNCLASSIFIED DRUG;

ANTIFUNGAL ACTIVITY; ARTICLE; BIOTRANSFORMATION; CARBON NUCLEAR MAGNETIC RESONANCE; CELL FREE SYSTEM; CONTROLLED STUDY; CROP; CRUCIFERA; DEFENSE MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; FUNGUS; FUNGUS CULTURE; GLYCOSYLATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MYCELIUM; NONHUMAN; NUCLEAR OVERHAUSER EFFECT; PLANT STRESS; PROTON NUCLEAR MAGNETIC RESONANCE; SCLEROTINIA SCLEROTIORIUM; SCREENING; STEM ROT; SYNTHESIS;

ANTIFUNGAL AGENTS; ASCOMYCOTA; CELL-FREE SYSTEM; DRUG DESIGN; GLUCOSYLTRANSFERASES; INDOLES; MOLECULAR STRUCTURE; PROTEIN KINASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP; TERPENES; THIOCARBAMATES;

SCLEROTINIA SCLEROTIORUM;

EID: 34447257929     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2007.05.072     Document Type: Article

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