Induction of antiviral genes, Mx and vig-1, by dsRNA and Chum salmon reovirus in rainbow trout monocyte/macrophage and fibroblast cell lines

Fish and Shellfish Immunology

Volumn 23, Issue 3, 2007, Pages 670-682

  DeWitte Orr, Stephanie J ^a   Leong, Jo Ann C ^b   Bols, Niels C ^a  

^a UNIVERSITY OF WATERLOO   (Canada)

^b UNIVERSITY OF HAWAII   (United States)

Author keywords

Antiviral; Chum salmon reovirus; Mx; Poly IC; Reovirus; RTG 2; RTS11; vig 1

Indexed keywords

COCKSFOOT STREAK VIRUS; ONCORHYNCHUS KETA; ONCORHYNCHUS MYKISS; ORTHOMYXOVIRIDAE; ORTHOREOVIRUS;

ANTIVIRUS AGENT; CYCLOHEXIMIDE; DOUBLE STRANDED RNA; FISH PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; MYXOVIRUS RESISTANCE PROTEINS; POLYCYTIDYLIC ACID; PROTEIN SYNTHESIS INHIBITOR; RIBAVIRIN;

ANIMAL; ARTICLE; CELL LINE; CULTURE MEDIUM; CYTOLOGY; DRUG EFFECT; FIBROBLAST; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; MACROPHAGE; METABOLISM; MONOCYTE; ONCORHYNCHUS KETA; RAINBOW TROUT; REOVIRUS; VIROLOGY;

ANIMALS; ANTIVIRAL AGENTS; CELL LINE; CULTURE MEDIA, CONDITIONED; CYCLOHEXIMIDE; FIBROBLASTS; FISH PROTEINS; GENE EXPRESSION REGULATION; GTP-BINDING PROTEINS; MACROPHAGES; MONOCYTES; ONCORHYNCHUS KETA; ONCORHYNCHUS MYKISS; POLY C; PROTEIN SYNTHESIS INHIBITORS; REOVIRIDAE; RIBAVIRIN; RNA, DOUBLE-STRANDED;

EID: 34447253547     PISSN: 10504648     EISSN: 10959947     Source Type: Journal    
DOI: 10.1016/j.fsi.2007.01.017     Document Type: Article

References (54)

1. Lockhart K., Bowden T.J., and Ellis A.E. Poly I:C-induced Mx responses in Atlantic salmon parr, post-smolts and growers. Fish Shellfish Immunol 17 (2004) 245-254
2. Salinas I., Lockhart K., Bowden T.J., Collet B., Secombes C.J., and Ellis A.E. An assessment of immunostimulants as Mx inducers in Atlantic salmon (Salmo salar L.) parr and the effect of temperature on the kinetics of Mx responses. Fish Shellfish Immunol 17 (2004) 159-170
3. Leong J.C., Trobridge G.D., Kim C.H.Y., Johnson M., and Simon B. Interferon-inducible Mx proteins in fish. Immunol Rev 166 (1998) 349-363
4. Lindenmann J. Resistance of mice to mouse-adapted influenza A virus. Virol 16 (1962) 203-204
5. Lee S.H., and Vidal S.M. Functional diversity of Mx proteins: variations on a theme of host resistance to infection. Genome Res 12 (2002) 527-530
6. Trobridge G.D., Chiou P.P., and Leong J.C. Cloning of the rainbow trout (Oncorhynchus mykiss) Mx2 and Mx3 cDNAs and characterization of trout Mx protein expression in Salmon cells. J Virol 71 (1997) 5304-5311
7. Larsen R., Rokenes T., and Robertsen B. Inhibition of infectious pancreatic necrosis virus replication by Atlantic salmon Mx1 protein. J Virol 78 (2004) 7938-7944
8. Kibenge M.T., Munir K., and Kibenge F.S. Constitutive expression of Atlantic salmon Mx1 protein in CHSE-214 cells confers resistance to infectious salmon anemia virus. Virol J 2 (2005) 75
9. Boudinot P., Massin P., Blanco M., Riffault S., and Benmansour A. vig-1, a new fish genes induced by the rhabdovirus glycoprotein, has a virus-induced homologue in humans and shares conserved motifs with the MoaA family. J Virol 73 (1999) 1846-1852
10. Boudinot P., Riffault S., Salhi S., Carrat C., Sedlik C., Mahmoudi N., et al. Vesicular stomatitis virus and pseudorabies virus induce a vig1/cig5 homologue in mouse dendritic cells via different pathways. J Gen Virol 81 (2000) 2675-2682
11. Chin K.C., and Cresswell P. Viperin (cig5), an IFN-inducible antiviral protein directly induced by human cytomegalovirus. Proc Natl Acad Sci USA 98 (2001) 15125-15130
12. Eaton W.D. Anti-viral activity in four species of salmonids following exposure to poly inosinic:cytidylic acid. Dis Aquat Org 9 (1990) 193-198
13. Alonso M., and Leong J.C. Suppressive subtraction libraries to identify interferon-inducible genes in fish. Marine Biotechnol 4 (2002) 74-80
14. Essbauer S., and Ahne W. Viruses of lower vertebrates. J Vet Med 48 (2001) 403-475
15. Winton J.R., Lannan C.N., Fryer J.L., and Kimura T. Isolation of a new reovirus from Chum salmon in Japan. Fish Pathol 15 (1981) 155-162
16. La Patra S., Lauda K.A., and Jones G.R. Aquareovirus interference mediated resistance to infectious hematopoietic necrosis virus. Vet Res 26 (1995) 455-459
17. Der S.D., Zhou A., Williams B.R.G., and Silverman R.H. Identification of genes differentially regulated by interferon α, β, or gamma using oligonucleotide arrays. Proc Natl Acad Sci USA 95 (1998) 15623-15628
18. Sen G.C. Novel functions of interferon-induced proteins. Cancer Biol 10 (2000) 93-101
19. Peel A.L. PKR activation in neurodegenerative disease. J Neuropathol Exp Neurol 63 (2004) 97-105
20. Hansen J.D., and La Patra S. Induction of the rainbow trout MHC class I pathway during acute IHNV infection. Immunogenetics 54 (2002) 654-661
21. Nam B.H., Yamamoto E., Hirono I., and Aoki T. A survey of expressed genes in leukocytes of Japanese flounder, Paralichthys olivaceus infected with Hirame rhabdovirus. Dev Comp Immunol 24 (2000) 13-24
22. O'Farrell C., Vaghefi N., Cantonnet M., Buteau B., Boudinot P., and Benmansour A. Survey of transcript expression in rainbow trout leukocytes reveals a major contribution of interferon-responsive genes in the early response to a rhabdovirus infection. J Virol 76 16 (2002) 8040-8049
23. Purcell M.K., Kurath G., Garver K.A., Herwig R.P., and Winton J.R. Quantitative expression profiling of immune response genes in rainbow trout following infectious haematopoietic necrosis virus (IHNV) infection or DNA vaccination. Fish Shellfish Immunol 17 (2004) 447-462
24. Hu C.Y., Zhang Y.B., Huang G.P., Zhang Q.Y., and Gui J.F. Molecular cloning and characterization of a fish PKR-like gene from cultured CAB cells induced by UV-inactivated virus. Fish Shellfish Immunol 17 (2004) 353-366
25. Rothenburg S., Deigendesch N., Dittmar K., Koch-Nolte F., Haag F., Lowenhaupt K., et al. A PKR-like eukaryotic initiation factor 2a kinase from zebrafish contains Z-DNA binding domains instead of dsRNA binding domains. Proc Natl Acad Sci USA 102 (2005) 1602-1607
26. Garner J.N., Joshi B., and Jagus R. Characterization of rainbow trout and zebrafish eukaryotic initiation factor 2α and its response to endoplasmic reticulum stress and IPNV infection. Dev Comp Immunol 27 (2003) 217-231
27. DeWitte-Orr S.J., Zorzitto J.R., Sutton L.P., and Bols N.C. Preferential induction of apoptosis in the rainbow trout macrophage cell line, RTS11, by actinomycin D, cycloheximide and double stranded RNA. Fish Shellfish Immunol 18 (2005) 279-295
28. Ganassin R.C., and Bols N.C. Development of a monocyte/macrophage-like cell line, RTS11, from rainbow trout spleen. Fish Shellfish Immunol 8 (1998) 457-476
29. Bols N.C., and Lee L.E.J. Cell lines: availability, propagation and isolation. In: Hochachka P.W., and Mommsen T.P. (Eds). Biochemistry and Molecular Biology of Fishes (1994), Elsevier Science, Amsterdam 145-159
30. Karber J. Beitrag zur kollektiven behandlung pharmakologischer reihenversuch. Arch Exp Pathol Pharmakol 162 (1931) 480-483
31. Jammi N.V., Whitby L.R., and Beal P.A. Small molecule inhibitors of the RNA-dependent protein kinase. Biochem Biophys Res Commun 308 (2003) 50-57
32. DeWitte-Orr S.J., and Bols N.C. Cytopathic effects of chum salmon reovirus to salmonid epithelial, fibroblast and macrophage cell lines. Virus Res 126 (2007) 159-171
33. Nygaard R., Husgard S., Sommer A.I., Leong J.C., and Robertsen B. Induction of Mx protein by interferon and double-stranded RNA in salmonid cells. Fish Shellfish Immunol 10 (2000) 435-450
34. Tafalla C., Aranguren R., Secombes C.J., Figueras A., and Novoa B. Cloning and analysis of expression of a gilthead sea bream (Sparus aurata) Mx cDNA. Fish Shellfish Immunol 16 (2004) 11-24
35. Plant K.P., and Thune R.L. Cloning and characterization of a channel catfish (Ictalurus punctatus) Mx gene. Fish Shellfish Immunol 16 (2004) 391-405
36. Collet B., and Secombes C.J. The rainbow trout (Oncorhynchus mykiss) Mx1 promoter: structural and functional characterization. Eur J Biochem 268 (2001) 1577-1584
37. Sen G.C. Viruses and interferons. Annu Rev Microbiol 55 (2001) 255-281
38. Platanias L.C. Mechanisms of type-1- and type-II-interferon-mediated signalling. Nat Rev Immunol 5 (2005) 375-386
39. Shuai K., and Liu B. Regulation of Jak-STAT signaling in the immune system. Nat Rev Immunol 3 (2003) 900-911
40. Collet B., and Secombes C.J. Type I-interferon signalling in fish. Fish Shellfish Immunol 12 (2002) 389-397
41. Zhang Y., and Gui J. Molecular characterization and IFN signal pathway analysis of Carassius auratus CaSTAT1 identified from the cultured cells in response to virus infection. Dev Comp Immunol 28 (2004) 211-227
42. Sun B.J., and Nie P. Molecular cloning of the viperin gene and its promoter region from the mandarin fish Siniperca chuatsi. Vet Immunol Immunopathol 101 (2004) 161-170
43. Memet S., Besancon F., Bourgeade M.-F., and Thang M.N. Direct induction of interferon gamma and interferon-α/β-inducible genes by double-stranded RNA. J Interferon Res 11 (1991) 131-141
44. Decker T. Double-stranded RNA and interferon-α induce transcription through different molecular mechanisms. J Interferon Res 12 (1992) 445-448
45. Hu Y., and Conway T.W. 2-aminopurine inhibits the double-stranded RNA-dependent protein kinase both in vitro and in vivo. J Interferon Res 13 (1993) 323-328
46. Zhang Y.B., Li Q., and Gui J.F. Differential expression of two Carassius auratus Mx genes in cultured CAB cells induced by grass carp hemorrhage virus and interferon. Immunogenetics 56 (2004) 68-75
47. Lin O.E., Ohira T., Hirono I., Saito-Taki T., and Aoki T. Immunoanalysis of antiviral Mx protein expression in Japanese flounder (Paralichthys olivaceus) cells. Dev Comp Immunol 29 (2005) 443-455
48. Rankin J.T., Eppes S.B., Antczak J.B., and Joklik W.K. Studies on the mechanism of the antiviral activity of ribavirin against reovirus. Virology 168 (1989) 147-158
49. Stewart M.J., Blum M.A., and Sherry B. PKR's protective role in viral myocarditis. Virology 314 (2003) 92-100
50. Golden J.W., Bahe J.A., Lucas W.T., Nibert M.L., and Schiff L.A. Cathespin S supports acid-independent infection by some reoviruses. J Biol Chem 279 (2004) 8547-8557
51. Borsa J., Morash B.D., Sargent M.D., Copps T.P., Lievaart P.A., and Szekely J.G. Two modes of entry of reovirus particles into L cells. J Gen Virol 45 (1979) 161-170
52. Tosteson M.T., Nibert M.L., and Field B.N. Ion channels induced in lipid bilayers by subvirion particles of the nonenveloped mammalian reoviruses. Proc Natl Acad Sci USA 90 (1993) 10549-10552
53. Trobridge G.D., Chiou P.P., Kim C.H., and Leong J.C. Induction of the Mx protein of rainbow trout Oncorhynchus mykiss in vitro and in vivo with poly I:C dsRNA and infectious hematopoietic necrosis virus. Dis Aquat Org 30 (1997) 91-98
54. Jensen I., and Robertsen B. Effect of double-stranded RNA and interferon on the antiviral activity of Atlantic salmon cells against infectious salmon anemia virus and infectious pancreatic necrosis virus. Fish Shellfish Immunol 13 (2002) 221-241