A novel method to screen genomic libraries that combines genomic immunization with the prime-boost strategy

FEMS Immunology and Medical Microbiology

Volumn 50, Issue 3, 2007, Pages 430-433

  Yero, Daniel ^a,b   Pajón, Rolando ^b   Caballero, Evelin ^b   González, Sonia ^b   Cobas, Karem ^b   Fariñas, Mildrey ^a   Lopez, Yamilé ^a   Acosta, Armando ^a  

^a FINLAY INSTITUTE   (Cuba)

^b CENTER FOR GENETIC ENGINEERING AND BIOTECHNOLOGY   (Cuba)

Author keywords

Expression library immunization; Neisseria meningitidis; Outer membrane vesicles; Priming boost

Indexed keywords

BACTERIAL VACCINE; BACTERIUM ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY TITER; ARTICLE; BLOOD GROUP TYPING; COMPARATIVE STUDY; CONTROLLED STUDY; DNA IMMUNIZATION; EXPRESSION VECTOR; FEASIBILITY STUDY; GENE LIBRARY; GENETIC SCREENING; IMMUNIZATION; MEMBRANE VESICLE; MOUSE; NEISSERIA MENINGITIDIS; NONHUMAN; PRIORITY JOURNAL; RAT; SINGLE DRUG DOSE;

ANIMALS; ANTIGENS, BACTERIAL; BACTERIAL VACCINES; GENOMIC LIBRARY; IMMUNIZATION; MENINGOCOCCAL INFECTIONS; MICE; NEISSERIA MENINGITIDIS; RATS; SERUM;

EID: 34447252814     PISSN: 09288244     EISSN: 1574695X     Source Type: Journal    
DOI: 10.1111/j.1574-695X.2007.00265.x     Document Type: Article

References (17)

1. Barry MA, Howell DP, Andersson HA, Chen JL Singh RA (2004) Expression library immunization to discover and improve vaccine antigens. Immunol Rev 199: 68 83.
2. Bjune G, Hoiby EA, Gronnesby JK, Arnesen O, Fredriksen JH, Halstensen A, Holten E, Lindbak AK, Nokleby H Rosenqvist E (1991) Effect of outer membrane vesicle vaccine against group B meningococcal disease in Norway. Lancet 338: 1093 1096.
3. Delcayre A, Peake JS, White DJ, Yuan S, McDonald MK, Liang A, Tan PL Watson JD (2003) A genome-based functional screening approach to vaccine development that combines in vitro assays and DNA immunization. Vaccine 21: 3259 3264.
4. Frasch CE Robbins JD (1978) Protection against group B meningococcal disease. III. Immunogenicity of serotype 2 vaccines and specificity of protection in a guinea pig model. J Exp Med 147: 629 644.
5. Fredriksen JH, Rosenqvist E, Wedege E, Bryn K, Bjune G, Froholm LO, Lindbak AK, Mogster B, Namork E Rye U (1991) Production, characterization and control of MenB-vaccine "Folkehelsa": an outer membrane vesicle vaccine against group B meningococcal disease. NIPH Ann 14: 67 79.
6. Gioia CA, de Sousa AB, Cruz SC, Junior FC, Andrade AF, Sassi RM, Frasch CE Milagres LG (2005) Effect of a booster dose of serogroup B meningococcal vaccine on antibody response to Neisseria meningitidis in mice vaccinated with different immunization schedules. FEMS Immunol Med Microbiol 44: 35 42.
7. Hogarth PJ, Logan KE, Ferraz JC, Hewinson RG Chambers MA (2006) Protective efficacy induced by Mycobacterium bovis bacilli Calmette-Guerin can be augmented in an antigen independent manner by use of non-coding plasmid DNA. Vaccine 24: 95 101.
8. Krieg AM (2002) CpG motifs in bacterial DNA and their immune effects. Annu Rev Immunol 20: 709 760.
9. McCluskie MJ, Weeratna RD Davis HL (2000) The role of CpG in DNA vaccines. Springer Semin Immunopathol 22: 125 132.
10. Piedrafita D, Xu D, Hunter D, Harrison RA Liew FY (1999) Protective immune responses induced by vaccination with an expression genomic library of Leishmania major. J Immunol 163: 1467 1472.
11. Rosenqvist E, Hoiby EA, Wedege E, Bryn K, Kolberg J, Klem A, Ronnild E, Bjune G Nokleby H (1995) Human antibody responses to meningococcal outer membrane antigens after three doses of the Norwegian group B meningococcal vaccine. Infect Immun 63: 4642 4652.
12. Sierra GV, Campa HC, Varcacel NM, Garcia IL, Izquierdo PL, Sotolongo PF, Casanueva GV, Rico CO, Rodriguez CR Terry MH (1991) Vaccine against group B Neisseria meningitidis: protection trial and mass vaccination results in Cuba. NIPH Ann 14: 195 207.
13. Skeiky YA, Ovendale PJ, Jen S, Alderson MR, Dillon DC, Smith S, Wilson CB, Orme IM, Reed SG Campos-Neto A (2000) T cell expression cloning of a Mycobacterium tuberculosis gene encoding a protective antigen associated with the early control of infection. J Immunol 165: 7140 7149.
14. Talaat AM Stemke-Hale K (2005) Expression library immunization: a road map for discovery of vaccines against infectious diseases. Infect Immun 73: 7089 7098.
15. Vermont C van den Dobbelsteen G (2002) Neisseria meningitidis serogroup B: laboratory correlates of protection. FEMS Immunol Med Microbiol 34: 89 96.
16. Vermont CL, van Dijken HH, van Limpt CJ, de Groot R, van Alphen L van den Dobbelsteen GP (2002) Antibody avidity and immunoglobulin G isotype distribution following immunization with a monovalent meningococcal B outer membrane vesicle vaccine. Infect Immun 70: 584 590.
17. Yero CD, Pajón FR, Caballero ME, Cobas AK, Lopez HY, Fariñas MM, Gonzales BS Acosta DA (2005) Immunization of mice with Neisseria meningitidis serogroup B genomic expression libraries elicits functional antibodies and reduces the level of bacteremia in an infant rat infection model. Vaccine 23: 932 939.