Cerebrovascular reactivity to hypercapnia is unimpaired in breath-hold divers

Journal of Physiology

Volumn 582, Issue 2, 2007, Pages 723-730

  Ivancev, Vladimir ^a   Palada, Ivan ^a   Valic, Zoran ^a   Obad, Ante ^a   Bakovic, Darija ^a   Dietz, Niki M ^b   Joyner, Michael J ^b   Dujic, Zeljko ^a  

^a UNIVERSITY OF SPLIT   (Croatia)

^b Mayo Clinic   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; BLOOD CARBON DIOXIDE TENSION; BLOOD FLOW VELOCITY; BLOOD VESSEL REACTIVITY; BRAIN BLOOD VESSEL; BRAIN CIRCULATION; BRAIN HYPOXIA; BRAIN PROTECTION; BREATH HOLDING; BREATHING RATE; CARDIOVASCULAR PARAMETERS; CONGESTIVE CARDIOMYOPATHY; CONTROLLED STUDY; DIVER; HEART STROKE VOLUME; HEMODYNAMICS; HUMAN; HYPERCAPNIA; HYPEROXIA; HYPOTHESIS; MEAN ARTERIAL PRESSURE; MIDDLE CEREBRAL ARTERY; NORMAL HUMAN; PRIORITY JOURNAL; REBREATHING; REGULATORY MECHANISM; SLEEP APNEA SYNDROME; VASCULAR RESISTANCE; APNEA; BRAIN BLOOD FLOW; BRAIN VASCULAR RESISTANCE; CHRONIC INTERMITTENT HYPOXIA; DIVING; END TIDAL CARBON DIOXIDE TENSION; HUMAN EXPERIMENT;

ADULT; BLOOD FLOW VELOCITY; CARBON DIOXIDE; CARDIOVASCULAR SYSTEM; CEREBROVASCULAR CIRCULATION; DIVING; HUMANS; HYPERCAPNIA; HYPEROXIA; MIDDLE CEREBRAL ARTERY; PARTIAL PRESSURE; RESPIRATION; RESPIRATORY MECHANICS; VASCULAR RESISTANCE;

EID: 34447248785     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2007.128991     Document Type: Article

References (40)

1. Ameriso SF, Mohler JG, Suarez M & Fisher M (1994). Morning reduction of cerebral vasomotor reactivity. Neurology 44, 1907-1909.
2. Andersson JP, Liner MH, Fredsted A & Schagatay EK (2004). Cardiovascular and respiratory responses to apneas with and without face immersion in exercising humans. J Appl Physiol 96, 1005-1010.
3. 2 retention and inferior vena cava dilatation. J Appl Physiol 101, 866-872.
4. Bakovic D, Valic Z, Eterovic D, Vukovic I, Obad A, Marinovic-Terzic I & Dujic Z (2003). Spleen volume and blood flow response to repeated breath-hold apneas. J Appl Physiol 95, 1460-1466.
5. Bjurstrom RL & Schoene RB (1987). Control of ventilation in elite synchronized swimmers. J Appl Physiol 63, 1019-1024.
6. Dahl A, Russell D, Nyberg-Hansen R, Rootwelt K & Mowinckel P (1994). Simultaneous assessment of vasoreactivity using transcranial Doppler ultrasound and cerebral blood flow in healthy subjects. J Cereb Blood Flow Metab 14, 974-981.
7. Davis FM, Graves MP, Guy HJ, Prisk GK & Tanner TE (1987). Carbon dioxide response and breath-hold times in underwater hockey players. Undersea Biomed Res 14, 527-534.
8. Delapille P, Verin E, Tourny-Chollet C & Pasquis P (2001). Ventilatory responses to hypercapnia in divers and non-divers: Effects of posture and immersion. Eur J Appl Physiol 86, 97-103.
9. Diomedi M, Placidi F, Cupini LM, Bernardi G & Silvestrini M (1998). Cerebral hemodynamic changes in sleep apnea syndrome and effect of continuous positive airway pressure treatment. Neurology 51, 1051-1056.
10. Ferretti G (2001). Extreme human breath-hold diving. Eur J Appl Physiol 84, 254-271.
11. Florio JT, Morrison JB & Butt WS (1979). Breathing pattern and ventilatory response to carbon dioxide in divers. J Appl Physiol 46, 1076-1080.
12. Foster GE, Poulin MJ & Hanly PJ (2007). Intermittent hypoxia and vascular function: Implications for obstructive sleep apnoea. Exp Physiol 92, 51-65.
13. Garcia-Rio F, Pino JM, Ramirez T, Alvaro D, Alonso A, Villasante C & Villamor J (2002). Inspiratory neural drive response to hypoxia adequately estimates peripheral chemosensitivity in OSAHS patients. Eur Respir J 20, 724-732.
14. Georgiadis D, Sievert M, Cencetti S, Uhlmann F, Krivokuca M, Zierz S & Werdan K (2000). Cerebrovascular reactivity is impaired in patients with cardiac failure. Eur Heart J 21, 407-413.
15. Grassi B, Ferretti G, Costa M, Ferrigno M, Panzacchi A, Lundgren CE, Marconi C & Cerretelli P (1994). Ventilatory responses to hypercapnia and hypoxia in elite breath-hold divers. Respir Physiol 97, 323-332.
16. Hurford WE, Hong SK, Park YS, Ahn DW, Shiraki K, Mohri M & Zapol WM (1990). Splenic contraction during breath-hold diving in the Korean ama. J Appl Physiol 69, 932-936.
17. Iadecola C & Zhang F (1994). Nitric oxide-dependent and - independent components of cerebrovasodilation elicited by hypercapnia. Am J Physiol Regul Integr Comp Physiol 266, R546-R552.
18. Ip MS, Lam B, Chan LY, Zheng L, Tsang KW, Fung PC & Lam WK (2000). Circulating nitric oxide is suppressed in obstructive sleep apnea and is reversed by nasal continuous positive airway pressure. Am J Respir Crit Care Med 162, 2166-2171.
19. Jellema WT, Wesseling KH, Groeneveld AB, Stoutenbeek CP, Thijs LG & van Lieshout JJ (1999). Continuous cardiac output in septic shock by simulating a model of the aortic input impedance: A comparison with bolus injection thermodilution. Anesthesiology 90, 1317-1328.
20. Klingelhofer J, Hajak G, Sander D, Schulz-Varszegi M, Ruther E & Conrad B (1992). Assessment of intracranial hemodynamics in sleep apnea syndrome. Stroke 23, 1427-1433.
21. Lavie L (2003). Obstructive sleep apnoea syndrome - an oxidative stress disorder. Sleep Med Rev 7, 35-51.
22. Lin YC, Shida KK & Hong SK (1983). Effects of hypercapnia, hypoxia, and rebreathing on circulatory response to apnea. J Appl Physiol 54, 172-177.
23. Liner MH, Ferrigno M & Lundgren CE (1993). Alveolar gas exchange during simulated breath-hold diving to 20 m. Undersea Hyperb Med 20, 27-38.
24. 2 in sleep apnea patients. Sleep 7, 97-109.
25. Masuda Y, Yoshida A, Hayashi F, Sasaki K & Honda Y (1981). The ventilatory responses to hypoxia and hypercapnia in the Ama. Jpn J Physiol 31, 187-197.
26. Masuda Y, Yoshida A, Hayashi F, Sasaki K & Honda Y (1982). Attenuated ventilatory responses to hypercapnia and hypoxia in assisted breath-hold drivers (Funado). Jpn J Physiol 32, 327-336.
27. Meadows GE, Dunroy HM, Morrell MJ & Corfield DR (2003). Hypercapnic cerebral vascular reactivity is decreased, in humans, during sleep compared with wakefulness. J Appl Physiol 94, 2197-2202.
28. Meadows GE, Kotajima F, Vazir A, Kostikas K, Simonds AK, Morrell MJ & Corfield DR (2005). Overnight changes in the cerebral vascular response to isocapnic hypoxia and hypercapnia in healthy humans: protection against stroke. Stroke 36, 2367-2372.
29. Netzer N, Werner P, Jochums I, Lehmann M & Strohl KP (1998). Blood flow of the middle cerebral artery with sleep-disordered breathing: correlation with obstructive hypopneas. Stroke 29, 87-93.
30. Neubauer JA (2001). Invited review: Physiological and pathophysiological responses to intermittent hypoxia. J Appl Physiol 90, 1593-1599.
31. Niwa K, Haensel C, Ross ME & Iadecola C (2001). Cyclooxygenase-1 participates in selected vasodilator responses of the cerebral circulation. Circ Res 88, 600-608.
32. Placidi F, Diomedi M, Cupini LM, Bernardi G & Silvestrini M (1998). Impairment of daytime cerebrovascular reactivity in patients with obstructive sleep apnoea syndrome. J Sleep Res 7, 288-292.
33. Poulin MJ & Robbins PA (1996). Indexes of flow and cross-sectional area of the middle cerebral artery using doppler ultrasound during hypoxia and hypercapnia in humans. Stroke 27, 2244-2250.
34. Qureshi AI, Christopher WW & Bliwise DL (1999). Sleep fragmentation and morning cerebrovasomotor reactivity to hypercapnia. Am J Respir Crit Care Med 160, 1244-1247.
35. Read DJ (1967). A clinical method for assessing the ventilatory response to carbon dioxide. Australas Ann Med 16, 20-32.
36. Schagatay E, Haughey H & Reimers J (2005). Speed of spleen volume changes evoked by serial apneas. Eur J Appl Physiol 93, 447-452.
37. Serrador JM, Picot PA, Rutt BK, Shoemaker JK & Bondar RL (2000). MRI measures of middle cerebral artery diameter in conscious humans during simulated orthostasis. Stroke 31, 1672-1678.
38. Spicuzza L, Bernardi L, Calciati A & Di Maria GU (2003). Autonomic modulation of heart rate during obstructive versus central apneas in patients with sleep-disordered breathing. Am J Respir Crit Care Med 167, 902-910.
39. Valic Z, Palada I, Bakovic D, Valic M, Mardesic-Brakus S & Dujic Z (2006). Muscle oxygen supply during cold face immersion in breath-hold divers and controls. Aviat Space Environ Med 77, 1224-1229.
40. Wolk R & Somers VK (2003). Cardiovascular consequences of obstructive sleep apnea. Clin Chest Med 24, 195-205.