Transcranial electrical and magnetic stimulation of the brain: Basic physiological mechanisms

Magnetic Stimulation in Clinical Neurophysiology

Volumn , Issue , 2005, Pages 43-60

  Rothwell, John C ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

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EID: 34447248674     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-7506-7373-0.50007-9     Document Type: Chapter

References (71)

1. Kernell D, Chien-Ping WU Responses of the pyramidal tract to stimulation of the baboon's motor cortex. J Physiol 1967, 191:653-672.
2. Patton HD, Amassian VE Single and multiple unit analysis of the cortical stage of pyramidal tract activation. J Neurophysiol 1954, 17:345-363.
3. Amassian VE, Stewart M, Quirk GJ, et al. Physiological basis of motor effects of a transient stimulus to cerebral cortex. Neurosurgery 1987, 20:74-93.
4. Rothwell JC Techniques and mechanisms of action of transcranial stimulation of the human motor cortex. J Neurosci Methods 1997, 74:113-122.
5. Edgley SA, Eyre JA, Lemon RN, et al. Direct and indirect activation of corticospinal neurons by electrical and magnetic stimulation in the anesthetized macaque monkey. J Physiol (Lond) 1992, 446:224.
6. Gray CM, McCormick DA Chattering cells: superficial pyramidal neurons contributing to the generation of synchronous oscillations in the visual cortex. Science 1996, 274:109-113.
7. Jankowska E, Padel Y, Tanaka R The mode of activation of pyramidal tract cells by intracortical stimuli. J Physiol 1975, 249:617-636.
8. Merton PA, Morton HB Stimulation of the cerebral cortex in the intact human subject. Nature 1980, 285:227.
9. Amassian VE, Cracco RQ Human cerebral cortical responses to contralateral transcranial stimulation. Neurosurgery 1987, 20:148-155.
10. Starr A, Caramia MD, Zarola F, et al. Enhancement of motor cortical excitability in humans by non-invasive electrical stimulation appears before voluntary movement. Electroencephalogr Clin Neurophysiol 1988, 70:26-32.
11. Day BL, Dressler D, de Maertens NA, et al. Electric and magnetic stimulation of human motor cortex: surface EMG and single motor unit responses [published erratum appears in J Physiol (Lond) 1990;430:617]. J Physiol (Lond) 1989, 412:449-473.
12. Di Lazzaro V, et al. The physiological basis of transcranial motor cortex stimulation in conscious humans. Clin Neurophysiol 2004, 115:255.
13. Burke D, Hicks R, Gandevia SC, et al. Direct comparison of corticospinal volleys in human subjects to transcranial magnetic and electrical stimulation [published erratum appears in J Physiol (Lond) 1994;476:553]. J Physiol (Lond) 1993, 470:383-393.
14. Ugawa Y, Rothwell JC, Day BL, et al. Percutaneous electrical stimulation of corticospinal pathways at the level of the pyramidal decussation in humans. Ann Neurol 1991, 29:418-427.
15. Rothwell J, Burke D, Hicks R, et al. Transcranial electrical stimulation of the motor cortex in man: further evidence for the site of activation. J Physiol 1994, 481(Pt 1):243-250.
16. Mills KR, Boniface SJ, Schubert M Magnetic brain stimulation with a double coil: the importance of coil orientation. Electroencephalogr Clin Neurophysiol 1992, 85:17-21.
17. Tofts PS The distribution of induced currents in magnetic stimulation of the nervous system. Phys Med Biol 1990, 35:1119-1128.
18. Di Lazzaro V, Oliviero A, Saturno E, et al. The effect on corticospinal volleys of reversing the direction of current induced in the motor cortex by transcranial magnetic stimulation. Exp Brain Res 2001, 138:268-273.
19. Sakai K, Ugawa Y, Terao Y, et al. Preferential activation of different I waves by transcranial magnetic stimulation with a figure-of-eight-shaped coil. Exp Brain Res 1997, 113:24-32.
20. Rothwell JC, Day BL, Amassian VE Near threshold electrical and magnetic transcranial stimuli activate overlapping sets of cortical-neurons in humans. J Physiol (Lond) 1992, 452:109.
21. Di Lazzaro V, Oliviero A, Profice P, et al. Effects of voluntary contraction on descending volleys evoked by transcranial electrical stimulation over the motor cortex hand area in conscious humans. Exp Brain Res 1999, 124:525-528.
22. Day BL, Rothwell JC, Thompson PD, et al. Motor cortex stimulation in intact man. 2. Multiple descending volleys. Brain 1987, 110:1191-1209.
23. Thompson PD, Day BL, Rothwell JC, et al. The interpretation of electromyographic responses to electrical stimulation of the motor cortex in diseases of the upper motor neurone. J Neurol Sci 1987, 80:91-110.
24. Gandevia SC, Rothwell JC Knowledge of motor commands and the recruitment of human motoneurons. Brain 1987, 110:1117-1130.
25. Di Lazzaro V, Oliviero A, Pilato F, et al. Descending volleys evoked by transcranial magnetic stimulation of the brain in conscious humans: effects of coil shape. Clin Neurophysiol 2002, 113:114-119.
26. Kammer T, Beck S, Thielscher A, et al. Motor thresholds in humans: a transcranial magnetic stimulation study comparing different pulse waveforms, current directions and stimulator types. Clin Neurophysiol 2001, 112:250-258.
27. Maccabee PJ, Nagarajan SS, Amassian VE, et al. Influence of pulse sequence, polarity and amplitude on magnetic stimulation of human and porcine peripheral nerve. J Physiol 1998, 513(Pt 2):571-585.
28. Priori A, Bertolasi L, Dressler D, et al. Transcranial electric and magnetic stimulation of the leg area of the human motor cortex: single motor unit and surface EMG responses in the tibialis anterior muscle. Electroencephalogr Clin Neurophysiol 1993, 89:131-137.
29. Di Lazzaro V, Oliviero A, Profice P, et al. Descending spinal cord volleys evoked by transcranial magnetic and electrical stimulation of the motor cortex leg area in conscious humans. J Physiol 2001, 537:1047-1058.
30. Nielsen J, Petersen N, Ballegaard M Latency of effects evoked by electrical and magnetic brain stimulation in lower limb motoneurones in man. J Physiol (Lond) 1995, 484:791-802.
31. Terao Y, Ugawa Y, Sakai K, et al. Transcranial stimulation of the leg area of the motor cortex in humans. Acta Neurol Scand 1994, 89:378-383.
32. Kujirai T, Caramia MD, Rothwell JC, et al. Corticocortical inhibition in human motor cortex. J Physiol (Lond) 1993, 471:501-519.
33. Hanajima R, Ugawa Y, Terao Y, et al. Paired-pulse magnetic stimulation of the human motor cortex: differences among I waves. J Physiol (Lond) 1998, 509:607-618.
34. Orth M, Snijders AH, Rothwell JC The variability of intracortical inhibition and facilitation. Clin Neurophysiol 2003, 114:2362-2369.
35. Fisher RJ, Nakamura Y, Bestmann S, et al. Two phases of intracortical inhibition revealed by transcranial magnetic threshold tracking. Exp Brain Res 2002, 143:240-248.
36. Bestmann S, et al. Inhibitory interactions between pairs of subthreshold conditioning stimuli in the human motor cortex. Clin Neurophysiol 2004, 115:755.
37. Ashby P, Reynolds C, Wennberg R, et al. On the focal nature of inhibition and facilitation in the human motor cortex. Clin Neurophysiol 1999, 110:550-555.
38. Di Lazzaro V, Oliviero A, Meglio M, et al. Direct demonstration of the effect of lorazepam on the excitability of the human motor cortex. Clin Neurophysiol 2000, 111:794-799.
39. Tokimura H, Ridding MC, Tokimura Y, et al. Short latency facilitation between pairs of threshold magnetic stimuli applied to human motor cortex. Electroencephalogr Clin Neurophysiol 1996, 101:263-272.
40. Ziemann U, Tergau F, Wassermann EM, et al. Demonstration of facilitatory I wave interaction in the human motor cortex by paired transcranial magnetic stimulation. J Physiol (Lond) 1998, 511:181-190.
41. Amassian VE, Rothwell JC, Cracco RQ, et al. What is excited by near-threshold twin magnetic stimuli over human cerebral cortex?. J Physiol (Lond) 1998, 506P:122.
42. Ilic TV, Meintzschel F, Cleff U, et al. Short-interval paired-pulse inhibition and facilitation of human motor cortex: the dimension of stimulus intensity. J Physiol 2002, 545:153-167.
43. Ziemann U, Rothwell JC, Ridding MC Interaction between intracortical inhibition and facilitation in human motor cortex. J Physiol 1996, 496(Pt 3):873-881.
44. Valls-Sole J, Pascual-Leone A, Wassermann EM, et al. Human motor evoked responses to paired transcranial magnetic stimuli. Electroencephalogr Clin Neurophysiol 1992, 85:355-364.
45. Werhahn KJ, Kunesch E, Noachtar S, et al. Differential effects on motor cortical inhibition induced by blockade of GABA uptake in humans. J Physiol (Lond) 1999, 517:591-597.
46. Chen R, Lozano AM, Ashby P Mechanism of the silent period following transcranial magnetic stimulation. Evidence from epidural recordings. Exp Brain Res 1999, 128:539-542.
47. Di Lazzaro V, Oliviero A, Mazzone P, et al. Direct demonstration of long latency cortico-cortical inhibition in normal subjects and in a patient with vascular parkinsonism. Clin Neurophysiol 2002, 113:1673-1679.
48. Nakamura H., Kitagawa H, Kawaguchi Y, et al. Intracortical facilitation and inhibition after transcranial magnetic stimulation in conscious humans. J Physiol (Lond) 1997, 498:817-823.
49. Werhahn KJ, Mortensen J, Kaelin-Lang A, et al. Cortical excitability changes induced by deafferentation of the contralateral hemisphere. Brain 2002, 125:1402-1413.
50. Ferbert A, Priori A, Rothwell JC, et al. Interhemispheric inhibition of the human motor cortex. J Physiol (Lond) 1992, 453:525-546.
51. Hanajima R, Ugawa Y, Machii K, et al. Interhemispheric facilitation of the hand motor area in humans. J Physiol 2001, 531:849-859.
52. Meyer BU, Roricht S, von Grafin EH, et al. Inhibitory and excitatory interhemispheric transfers between motor cortical areas in normal humans and patients with abnormalities of the corpus callosum. Brain 1995, 118:429-440.
53. Boroojerdi B, Diefenbach K, Ferbert A Transcallosal inhibition in cortical and subcortical cerebral vascular lesions. J Neurol Sci 1996, 144:160-170.
54. Gerloff C, Cohen LG, Floeter MK, et al. Inhibitory influence of the ipsilateral motor cortex on responses to stimulation of the human cortex and pyramidal tract. J Physiol (Lond) 1998, 510:249-259.
55. Daskalakis ZJ, Christensen BK, Fitzgerald PB, et al. The mechanisms of interhemispheric inhibition in the human motor cortex. J Physiol 2002, 543:317-326.
56. Gilio F, Rizzo V, Siebner HR, et al. Effects on the right motor hand-area excitability produced by low-frequency rTMS over human contralateral homologous cortex. J Physiol 2003, 551:563-573.
57. Delwaide PJ, Olivier E Conditioning transcranial cortical stimulation (TCCS) by exteroceptive stimulation in parkinsonian patients. Adv Neurol 1990, 53:175-181.
58. Tokimura H, Di Lazzaro V, Tokimura Y, et al. Short latency inhibition of human hand motor cortex by somatosensory input from the hand. J Physiol 1990, 523(Pt 2):503-513.
59. Di Lazzaro V, Oliviero A, Tonali PA, et al. Noninvasive in vivo assessment of cholinergic cortical circuits in AD using transcranial magnetic stimulation. Neurology 2002, 59:392-397.
60. Tamburin S, Manganotti P, Zanette G, et al. Cutaneomotor integration in human hand motor areas: somatotopic effect and interaction of afferents. Exp Brain Res 2001, 141:232-241.
61. Civardi C, Cantello R, Asselman P, et al. Transcranial magnetic stimulation can be used to test connections to primary motor areas from frontal and medial cortex in humans. Neuroimage 2001, 14:1444-1453.
62. Ugawa Y, Day BL, Rothwell JC, et al. Modulation of motor cortical excitability by electrical stimulation over the cerebellum in man. J Physiol (Lond) 1991, 441:57-72.
63. Ugawa Y, Uesaka Y, Terao Y, et al. Magnetic stimulation over the cerebellum in humans. Ann Neurol 1995, 37:703-713.
64. Pinto AD, Chen R Suppression of the motor cortex by magnetic stimulation of the cerebellum. Exp Brain Res 2001, 140:505-510.
65. Meyer BU, Roricht S, Machetanz J Reduction of corticospinal excitability by magnetic stimulation over the cerebellum in patients with large defects of one cerebellar hemisphere. Electroencephalogr Clin Neurophysiol 1994, 93:372-379.
66. Meyer BU, Roricht S Scalp potentials recorded over the sensorimotor region following magnetic stimulation over the cerebellum in man: considerations about the activated structures and their potential diagnostic use [letter] [see comments]. J Neurol 1995, 242:109-112.
67. Rothwell JC, Werhahn KJ, Amassian VE Additional source of potentials recorded from the scalp following magnetic stimulation over the lower occiput and adjoining neck. J Neurol 1995, 242:713-714.
68. Werhahn KJ, Taylor J, Ridding M, et al. Effect of transcranial magnetic stimulation over the cerebellum on the excitability of human motor cortex. Electroencephalogr Clin Neurophysiol 1996, 101:58-66.
69. Chen R Interactions between inhibitory and excitatory circuits in the human motor cortex. Exp Brain Res 2004, 154(1):1-10.
70. Rothwell JC, Thompson PD, Day BL, et al. Stimulation of the human motor cortex through the scalp. Exp Physiol 1991, 76:159-200.
71. Di Lazzaro V, Oliviero A, Profice P, et al. Comparison of descending volleys evoked by transcranial magnetic and electric stimulation in conscious humans. Electroencephalogr Clin Neurophysiol 1998, 109:397-401.