Tumor regression in mesorectal lymphnodes after neoadjuvant chemoradiation for rectal cancer

European Journal of Surgical Oncology

Volumn 33, Issue 6, 2007, Pages 724-728

  Caricato, M ^a   Ausania, F ^a   De Dominicis, E ^a   Vincenzi, B ^a   Rabitti, C ^a   Tonini, G ^a   Cellini, F ^a   Coppola, R ^a  

^a UNIVERSITY CAMPUS BIO MEDICO   (Italy)

Author keywords

Chemoradiation therapy; Lymphnode regression grade (LRG); Lymphnodes metastasis; Mesorectum; Rectal cancer; Tumor regression grade

Indexed keywords

ANTINEOPLASTIC AGENT; CISPLATIN; FLUOROURACIL;

ARTICLE; CANCER ADJUVANT THERAPY; CANCER GRADING; CANCER INVASION; CANCER REGRESSION; CLINICAL ARTICLE; CONTINUOUS INFUSION; CORRELATIONAL STUDY; FEMALE; FIBROSIS; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; MALE; OUTCOME ASSESSMENT; PREOPERATIVE EVALUATION; PREOPERATIVE TREATMENT; PRIORITY JOURNAL; PROGNOSIS; RECTUM CANCER; RECTUM SURGERY; SCORING SYSTEM;

ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CHEMOTHERAPY, ADJUVANT; DOSE FRACTIONATION; FEMALE; FIBROSIS; HUMANS; LYMPH NODES; LYMPHATIC METASTASIS; MALE; NEOADJUVANT THERAPY; NEOPLASM STAGING; NEOPLASM, RESIDUAL; PERITONEUM; RADIOTHERAPY, ADJUVANT; RECTAL NEOPLASMS; RECTUM; REMISSION INDUCTION; RETROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 34447125720     PISSN: 07487983     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejso.2007.01.023     Document Type: Article

References (13)

1. Mandard A.M., Dalibard F., Mandard J.C., et al. Pathologic assessment of tumor regression after preoperative chemoradiotherapy of esophageal carcinoma. Clinicopathologic correlations. Cancer 73 11 (Jun 1 1994) 2680-2686
2. Perez R.O., Habr-Gama A., Nishida Arazawa S.T., et al. Lymph node micrometastasis in stage II distal rectal cancer following neoadjuvant chemoradiation therapy. Int J Colorectal Dis 20 5 (Sep 2005) 434-439
3. Hughes R., Glynne-Jones R., Grainger J., et al. Can pathological complete response in the primary tumour following pre-operative pelvic chemoradiotherapy for T3-T4 rectal cancer predict for sterilisation of pelvic lymph nodes, a low risk of local recurrence and the appropriateness of local excision?. Int J Colorectal Dis 21 1 (Jan 2006) 11-17
4. Read T.E., Andujar J.E., Caushaj P.F., et al. Neoadjuvant therapy for rectal cancer: histologic response of the primary tumor predicts nodal status. Dis Colon Rectum 47 6 (Jun 2004) 825-831
5. Valentini V., Coco C., Cellini N., et al. Preoperative chemoradiation with cisplatin and 5-fluorouracil for extraperitoneal T3 rectal cancer: acute toxicity, tumor response, sphincter preservation. Int J Radiat Oncol Biol Phys 45 5 (Dec 1 1999) 1175-1184
6. Salzer-Kuntschik M., Delling G., Beron G., and Sigmund R. Morphological grades of regression in osteosarcoma after polychemotherapy - study COSS 80. J Cancer Res Clin Oncol 106 Suppl (1983) 21-24
7. Braun O.M., Neumeister B., Popp W., et al. Histologic tumor regression grades in squamous cell carcinoma of the head and neck after preoperative radiochemotherapy. Cancer 63 6 (Mar 15 1989) 1097-1100
8. Bouzourene H., Bosman F.T., Seelentag W., Matter M., and Coucke P. Importance of tumor regression assessment in predicting the outcome in patients with locally advanced rectal carcinoma who are treated with preoperative radiotherapy. Cancer 94 4 (Feb 15 2002) 1121-1130
9. Newman L.A., Pernick N.L., Adsay V., et al. Histopathologic evidence of tumor regression in the axillary lymph nodes of patients treated with preoperative chemotherapy correlates with breast cancer outcome. Ann Surg Oncol 10 7 (Aug 2003) 734-739
10. Vecchio F.M., Valentini V., Minsky B.D., et al. The relationship of pathologic tumor regression grade (TRG) and outcomes after preoperative therapy in rectal cancer. Int J Radiat Oncol Biol Phys 62 3 (Jul 1 2005) 752-760
11. Wheeler J.M., Dodds E., Warren B.F., et al. Preoperative chemoradiotherapy and total mesorectal excision surgery for locally advanced rectal cancer: correlation with rectal cancer regression grade. Dis Colon Rectum 47 12 (Dec 2004) 2025-2031
12. Rodel C., Martus P., Papadoupolos T., et al. Prognostic significance of tumor regression after preoperative chemoradiotherapy for rectal cancer. J Clin Oncol 23 34 (Dec 1 2005) 8688-8696
13. Kim D.W., Kim D.Y., Kim T.H., et al. Is T classification still correlated with lymph node status after preoperative chemoradiotherapy for rectal cancer?. Cancer 106 8 (Apr 15 2006) 1694-1700