Glycobiochemical characterization of salivary carcinoembryonic antigen

Journal of B.U.ON.

Volumn 12, Issue 2, 2007, Pages 269-275

  Golubovic, S ^a   Jankovic, Miroslava ^a  

^a UNIVERSITY OF BELGRADE   (Serbia)

Author keywords

Cancer; Carcinoembryonic antigen; Glycosylation; Lectin; Saliva

Indexed keywords

AGGLUTININ; CARCINOEMBRYONIC ANTIGEN; PLANT LECTIN; SEPHAROSE;

AFFINITY CHROMATOGRAPHY; ANTIGEN DETECTION; ANTIGEN STRUCTURE; ARTICLE; CANCER; CONTROLLED STUDY; GEL FILTRATION; GENETIC HETEROGENEITY; HUMAN; IMMUNOAFFINITY CHROMATOGRAPHY; MOLECULAR WEIGHT; PEA; PHASEOLUS VULGARIS; POLYACRYLAMIDE GEL ELECTROPHORESIS; SALIVA ANALYSIS;

ADENOCARCINOMA; CARCINOEMBRYONIC ANTIGEN; CELL LINE; CHROMATOGRAPHY, AFFINITY; CHROMATOGRAPHY, GEL; COLONIC NEOPLASMS; HUMANS; RADIOIMMUNOASSAY; SALIVA; SEPHAROSE;

EID: 34447122201     PISSN: 11070625     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (46)

1. Gold P, Freedman SO. Specific carcinoembryonic antigens of the human digestive system. J Exp Med 1965; 122: 467-481.
2. Thompson JA. Molecular cloning and expression of carcinoembryonic antigen gene family members. Tumor Biol 1995; 16: 10-16.
3. Thomas P, Toth CA, Saini KS, Jessup JM, Steele G Jr. The structure, metabolism and function of the carcinoembryonic antigen gene family. Biochim Biophys Acta 1990; 1032: 177-189.
4. Barnett T, Zimmermann W. Workshop report. Proposed nomenclature for the carcinoembryonic antigen (CEA) gene family. Tumor Biol 1990; 11: 59-63.
5. Beauchemin N, Draber P, Dveksler G et al. Redefined nomenclature for members of the carcinoembryonic antigen family. Exp Cell Res 1999; 252: 243-249.
6. Obrink B. CEA adhesion molecules: multifunctional proteins with signal-regulatory properties. Curr Opin Cell Biol 1997; 9: 616-626.
7. 1-glycoprotein: a new member of the carcinoembryonic antigen gene family. Biochem Biophys Res Commun 1988; 152: 762-768.
8. Benchimol S, Fuks A, Jothy S, Beauchemin N, Shirota K, Stanners CP. Carcinoembryonic antigen, a human tumor marker: function as an intercellular adhesion molecule. Cell 1989; 57: 327-334.
9. Pignatelli M, Durbin H, Bodmer WF. Carcinoembryonic antigen functions as an accessory adhesion molecule mediating colon epithelial cell-colagen interactions. Proc Natl Acad Sci 1990; 87: 1541-1545.
10. Leusch HG, Hefta SA, Drzeniek Z, Humel K, Markos-Pusztai Z, Wagener C. Escherichia coli of human origin binds to carcinoembryonic antigen (CEA) and non-specific crossreacting antigen (NCA). FEBS Letters 1990; 261: 405-409.
11. Ordonez C, Screaton RA, Ilantzis C, Stanners CP. Human carcinoembryonic antigen functions as a general inhibitor of anoikis. Cancer Res 2003; 60: 3419-3424.
12. Schmitter T, Agerer F, Peterson L, Munzner P, Hauck CR. Granulocyte CEACAM3 is phagocytic receptor of the innate immune system that mediates recognition and elimination of human-specific pathogens. J Exp Med 2004; 199: 35-46.
13. Von Kleist S, Chavanel G, Burtin P. Identification of an antigen from normal human tissue that crossreacts with the carcinoembryonic antigen. Proc Natl Acad Sci USA 1972; 69: 2492-2494.
14. Svenberg T. Carcinoembryonic antigen-like substances of human bile. Isolation and partial characterization. Int J Cancer 1976; 17: 588-596.
15. Nollau P, Scheller H, Kona-Horstmann et al. Expression of CD 66a (Human C-CAM) and other members of the carcinoembryonic antigen gene family of adhesion molecules in human colorectal adenomas. Cancer Res 1997; 57: 2354-2357.
16. Cvejic D, Savin S, Golubovic S, Paunovic J, Tatic S, Havelka M. Galectin-3 and carcinoembryonic antigen expression in medullary thyroid carcinoma: possible relation to tumor progression. Histopathology 2000; 37: 530-535.
17. Bozic M, Golubovic S, Petronijevic M, Vicovac Lj. Expression of galectin-3 and carcinoembryonic antigen in the trophoblast of the gestational trophoblastic disease. J BUON 2004; 9: 427-432.
18. Burtin P, Chavanel G, Hirsch-Marie H. Characterization of a second normal antigen that cross-react with CEA. J Immunol 1973; 111: 1926-1928.
19. Kuroki M, Koga Y, Matsuoka Y. Purification and characterization of carcinoembryonic antigen-related antigens in normal adult feces. Cancer Res 1981; 41: 713-720.
20. Sarandakou A, Phocas I, Botsis D, Rizos D, Trakakis E, Chryssikopulos A. Vaginal fluid and serum CEA, CA125 and SCC in normal conditions and in benign and malignant diseases of the genital tract. Acta Oncol 1997; 36: 755-759.
21. Hammarstrom S, Baranov V. Is there a role for CEA in innate immunity in the colon? Trends Microbiol 2001; 9: 19-25.
22. Vicovac Lj, Bozic M, Bojic-Trbojevic Z, Golubovic S. Carcinoembryonic antigen and related molecules in normal and transformed trophoblast. Placenta 2007; 28: 85-96.
23. Thompson A, Grunert F, Zimmermann W. Carcinoembryonic antigen gene family: molecular biology and clinical perspectives. J Clin Lab Analysis 1991; 5: 344-366.
24. Chandrasekaran EV, Davila M, Nixon DW, Goldfarb M, Mendicino J. Isolation and structures of the oligosaccharide units of carcinoembryonic antigen. J Biol Chem 1983; 258: 7213-7222.
25. Miura M, Fukuyima Y, Hirano T, Hirano M, Matsuzaki, Oka H. Sugar-chain multiformity of human carcinoembryonic antigen: difference between normal and tumor-associated subfractions. Clin Chem 1990; 35: 583-584.
26. Hampton R, Walker M, Marshall J, Juhl H. Differential expression of carcinoembryonic antigen (CEA) splice variants in whole blood of colon cancer patients and healthy volunteers: implication for the detection of circulating colon cancer cells. Oncogene 2002; 21: 7817-7823.
27. Zoubir F, Khan WN, Hammarstrom S. Carcinoembryonic antigen gene family members in submandibular salivary gland: demonstration of pregnancy-specific glycoproteins by cDNA cloning. Biochem Biophys Res Commun 1990; 169: 203-216.
28. Iwai M, Miyahara H. Normal human salivary gland cells produce carcinoembryonic antigen-related antigen in collagen gels. In Vitro Cell Dev Biol 1991; 27A: 759-762.
29. Halberg F, Haus E, Lakatua DJ, Antinozzi R, Cornelissen G. Cancer marker assessment in clinical health: case report on salivary and urinary CEA. In Vivo 1995; 9: 311-314.
30. Golubovic S, Marovic-Stojkovic V, Jankovic Lj. Immunohistochemical detection of carcinoembryonic antigen (CEA) in the epithelia of inflamed gingiva. Arch Oncol 1997; 5: 61-64.
31. Golubovic S, Jankovic Lj, Movsesijan A, Bojic Z, Jankovic M. Salivary carcinoembryonic antigen as an inflammatory marker. Jugoslav Med Biochem 2003; 22: 207-211.
32. Schenkels LCPM, Veerman ECI, Nieuw Amerongen AV. Biochemical composition of human saliva in relation to other mucosal fluids. Crit Rev Oral Biol Med 1995; 6: 161-175.
33. Tabak LA. In defence of the oral cavity: Structure, biosynthesis and function of salivary mucins. Annu Rev Physiol 1995; 57: 547-564.
34. Laemmli UK. Cleavage of structural proteins during the assembly of the head of the bacteriopbage T4. Nature 1970; 227: 680-685.
35. 131I-labelled human growth hormone of high specific radioactivity. Biochem J 1963; 89: 114-123.
36. Kobata A, Amano J. Altered glycosylation of proteins produced by malignant cells, and application for the diagnosis and immunotherapy of tumours. Immunol Cell Biol 2005; 83: 429-439.
37. Wojciechowicz DC, Park PY, Datta RV, Paty PB. CEA is the major PHA-L-reactive glycoprotein in colon carcinoma cell lines and tumors: relationship between K-ras activation and β1-6 branching of N-linked carbohydrate on CEA. Biochem Biophys Res Comm 2000; 273: 147-153.
38. Yamashita K, Totani K, Kuroki M, Matsuoka Y, Ueda I, Kobata A. Structural studies of the carbohydrate moieties of carcinoembryonic antigens. Cancer Res 1987; 47: 3451-3459.
39. Yamashita K, Totani K, Iwaki Y et al. Carbohydrate structures of nonspecific cross-reacting antigen-2, a glycoprotein purified from meconium as an antigen cross-reacting with anticarcinoembryonic antigen antibody. J Biol Chem 1989; 264: 17873-17881.
40. Fukushima K, Ohkura T, Kanai M et al. Carbohydrate structures of a normal counterpart of the careinoembryonic antigen produced by colon epithelial cells of normal adults. Glycobiol 1995; 5: 105-115.
41. Yamashita K, Fukushima K, Sakiyama T, Murata F, Kuroki M, Matsuoka Y. Expression of Siaα2→6Ga1β1→4GlcNAc residues on sugar chains of glycoproteins including carcinoembryonic; antigens in human colon adenocarcinoma: application of trichosanthes japonica agglutinin 1 for early diagnosis. Cancer Res 1995; 55: 1675-1679.
42. Brockhausen I, Kuhns W. Glycoproteins and Human Disease. Heidelberg: Medical Intelligence Unit, Springer, 1997.
43. Heffi A. Aspects of cell biology of the normal periodontium. Periodontology 2000; 1993; 3: 64-75.
44. Levine MJ. Salivary macromolecules: a structure/function synopsis. Ann N Y Acad Sci 1993; 694: 11-16.
45. Tabak LA. In defence of the oral cavity: the protective role of the salivary secretions. Pediatr Dent 2006; 29: 110-117.
46. Prado IB, Laudanna AA, Carneiro CRW. Susceptibility of colorectal-carcinoma cells to natural-killer-mediated lysis: relationship to CEA expression and degree of differentiation. Int J Cancer 1995; 61: 854-860.